RESUMEN
The polymorphism of alpha-2-HS-glycoprotein (AHSG, alpha 2HS) was analysed in a sample of New Zealanders consisting of 194 New Zealand Europeans and 236 New Zealand Maori. Thin layer polyacrylamide gel isoelectric focusing followed by immunofixation revealed four different AHSG phenotypes in New Zealand Europeans and three different AHSG phenotypes in New Zealand Maori. The AHSG*2 frequency of 0.695 for the New Zealand Maori population was found to be one of the highest reported for any population. AHSG*2 appears to be a useful genetic marker for Maori in anthropological studies.
Asunto(s)
Proteínas Sanguíneas/genética , Polimorfismo Genético , Alelos , Europa (Continente)/etnología , Frecuencia de los Genes , Humanos , Nueva Zelanda , Fenotipo , Población Blanca/genética , alfa-2-Glicoproteína-HSRESUMEN
Allele frequencies are reported for 19 blood group, red cell enzyme, and serum protein loci (ABO, Rh, MN, Hb-A, LDH-A, LDH-B, SOD, PGM-1, PGM-2, 6PGD, GPT, ESD, ADA, ACP, PGK, MDH, Alb, Hp, and Tf) determined from 310 blood samples collected among the Gainj, a small population of tribal horticulturalists from highland Papua New Guniea. Fourteen of these loci display genetic variants, and ten of them are sufficiently polymorphic to permit a preliminary analysis of Gainj population structure. Patterns of variation among subdivisions of the population are analyzed using an approach analogous to a multivariate analysis of variance with unbalanced design, and weighted genetic distances are extracted from the results. The distance analysis indicates that patterns of genetic variation within this population reflect the geographical distribution of subdivisions, as well as subdivision size and movement among subdivisions. A parallel analysis of the Gainj and two other tribal groups from highland New Guinea, the Murapin Enga and the Simbai Valley Maring, suggests that the Gainj are both genetically divergent from neighboring populations and internally highly differentiated.