RESUMEN
This study aims to assess the COVID-19 seroprevalence in HCW at the Hospital Central de la Defensa Gómez Ulla (HCDGU) (Madrid). From 27 April to 10 June 2020 nasopharyngeal swab and serum samples from employees were processed in order to evaluate their seroprevalence and infective situation. Employees were classified according to their exposure to SARS-CoV-2 infection as high, moderate, and low exposure groups (level 1, level 2, and level 3, respectively). A specific real-time polymerase chain reaction (RT-PCR) was run to diagnose each patient, whereas the qualitative detection of IgG antibodies to SARS-CoV-2 was performed by means of an immunoassay. In total, 2781 HCW were screened. From this sample, 30 employees (1.1%) were infected with SARS-CoV-2 and 450 (16.2%) were positive to SARS-CoV-2-IgG antibodies. The seroprevalence was higher in the high exposure group.The seroprevalence of antibodies against SARS-CoV-2 among employees without any COVID-19 training was higher than in those who received COVID-19 training (14.5% vs 18.6%, P = 0.035). The seroprevalence in military and civilian personnel in level 1 was 18.2% and 20.0%, respectively (P = 0.4616), while in level 2 it was 6.0% and 16.0% (P = 0.0008) and in level 3 it was 16.7% and 10.2% (P = 0.0315). The results from the present study have shown that the high exposure group and HCW not receiving specific training against COVID-19 showed higher seroprevalence. Furthermore, the military employees from this hospital presented low percentage of seroprevalence.
Asunto(s)
COVID-19 , SARS-CoV-2 , Anticuerpos Antivirales , Personal de Salud , Hospitales Militares , Humanos , Estudios Seroepidemiológicos , España , Estados UnidosRESUMEN
This is a case report of septic arthritis of the knee due to Prevotella loescheii, in a patient with advanced arthrosis. Two weeks beforehand he had undergone a dental root extraction without antibiotic prophylaxis. His knee had become inflamed 48 hours after extraction and he was started on ibuprofen and steroid treatment (prescribed by his primary health care doctor). With a provisional diagnosis of septic arthritis, synovial fluid was taken for study. Antimicrobial therapy was commenced with amoxicillin/clavulanic acid and the patient progressed satisfactorily. Prevotella loescheii was identified by anaerobic culture. A site of origin for the infection was never found. Joint infection is generally secondary to haematogenous dissemination of bacteria from habitual sites such as odontogenic locations. We suggest that patients with inflammatory arthropathies should be considered as candidates for antibiotic prophylaxis in oral surgery and invasive dental procedures. We suggest, in these cases, the use of antibiotic with spectrum against aerobic and anaerobic bacteria.
Asunto(s)
Artritis Infecciosa/microbiología , Infecciones por Bacteroidaceae/etiología , Articulación de la Rodilla , Prevotella , Extracción Dental/efectos adversos , Anciano , Humanos , MasculinoRESUMEN
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Asunto(s)
Humanos , Femenino , Adulto , Peptostreptococcus/patogenicidad , Miositis/microbiología , Infecciones por Bacterias Grampositivas/complicaciones , Hepatitis C Crónica/complicacionesRESUMEN
Antecedentes y objetivos: Desde la introducción en el siglo XIX del lavado de manos con agente antiséptico en la práctica médica, éste acto se ha hecho obligatorio en la práctica médica y los productos a utilizar son regulados por normativas específicas. Objetivo: Evaluar la actividad bactericida de Dermogel comparándola con un producto de referencia, según la norma UNE-EN 1500. Material y Métodos: Se precisó la participación de doce voluntarios para una contaminación controlada de las manos, con un inóculo de E.coli y se procedió al recuento de unidades formadoras de colonias (UFC) generadas tras la contaminación. Tras el lavado con un producto antiséptico de referencia se procedió a un nuevo recuento de UFC. El procedimiento se repitió con Dermogel. Resultados: Con los recuentos de UFC inicial (tras la contaminación) y final (tras la fricción con Dermogel y con el producto de referencia) se calculó el logaritmo de cada valor y del factor de reducción. Aplicando el test de Wilcoxon, se observa que los resultados con Dermogel son significativamente inferiores (p= 0.001) que los obtenidos con el producto de referencia. Conclusiones: Dermogel no cumple los requisitos establecidos por la citada norma para el tratamiento higiénico de las manos por fricción (AU)