RESUMEN
Five eudesmane-type sesquiterpenoids were isolated from the methanol extract of the aerial part of Tessaria integrifolia Ruiz. et Pavon (Compositae). Their structures were elucidated on the basis of spectroscopic analysis is well as chemical evidence.
Asunto(s)
Asteraceae/química , Naftalenos/aislamiento & purificación , Sesquiterpenos de Eudesmano , Sesquiterpenos , Activación Enzimática , Hialuronoglucosaminidasa/química , Espectroscopía de Resonancia Magnética , Naftalenos/química , Extractos Vegetales/químicaRESUMEN
Eight new labdane-type diterpenes (1-8) were isolated from the fruit of Vitex rotundifolia along with two known abietane-type diterpenoids (9, 10), and their structures were characterized on the basis of spectroscopic data and X-ray crystallographic analysis. Among them, the abietane-type diterpenoid ferruginol (9) exhibited a stronger antioxidative activity than the standard antioxidant, 3-tert-butyl-4-hydroxyanisole (BHA), using a ferric thiocyanate method.
Asunto(s)
Antioxidantes/química , Diterpenos/química , Frutas/química , Picratos , Plantas Medicinales/química , Antioxidantes/farmacología , Asia , Bepridil/análogos & derivados , Bepridil/química , Compuestos de Bifenilo , Secuencia de Carbohidratos , Cristalografía por Rayos X , Diterpenos/farmacología , Depuradores de Radicales Libres/química , Depuradores de Radicales Libres/farmacología , Radicales Libres , Espectroscopía de Resonancia Magnética , Conformación Molecular , Datos de Secuencia MolecularRESUMEN
Extracts of the atrial gland of the sea hare Aplysia californica (Mollusca) induce egg laying when injected into mature individuals. Since egg laying is controlled endogenously by a peptide secreted by neuroendocrine cells in the central nervous system, the relationship between the atrial gland and these central neurons has become an issue of interest. With the particular objective of examining secretory structures we undertook an ultrastructural study of the atrial gland and adjacent tissues. This study revealed that the atrial gland epithelium in composed of two major cell types: 'goblet-like' exocrine cells containing large electron-dense granules, and ciliated 'capping cells'. A non-secretory, and possibly post-secretory, cell containing electron-lucent granules was noted. A region of the large hermaphroditic duct contiguous ot the atrial gland, known as the red hemiduct, also displayed capping cells and secretory cells with large granules. The content of these granules is organized into crista-like condensations. The cell also contains iron-rich pigment inclusions.