RESUMEN
Measurement of flow velocity in the left anterior descending coronary artery by transesophageal echocardiography in subjects without risk factors for coronary artery disease (group 1) and in subjects with normal coronary arteries but conditions associated with endothelial dysfunction (group 2) revealed that there was a significantly impaired coronary flow velocity response to the cold pressor test in group 2 subjects. Thus, transesophageal echocardiography provides a minimally invasive tool for the functional assessment of endothelium and can be valuable in evaluating endothelial dysfunction and recovery in a variety of disease states.
Asunto(s)
Frío , Angiografía Coronaria , Circulación Coronaria , Vasos Coronarios/fisiología , Ecocardiografía Transesofágica , Endotelio Vascular/fisiología , Vasodilatación/fisiología , Adenosina/administración & dosificación , Adulto , Anciano , Velocidad del Flujo Sanguíneo/efectos de los fármacos , Circulación Coronaria/efectos de los fármacos , Enfermedad Coronaria/diagnóstico , Vasos Coronarios/diagnóstico por imagen , Vasos Coronarios/efectos de los fármacos , Ecocardiografía Doppler en Color , Endotelio Vascular/efectos de los fármacos , Prueba de Esfuerzo , Femenino , Humanos , Infusiones Intravenosas , Masculino , Persona de Mediana Edad , Factores de Riesgo , Vasodilatación/efectos de los fármacos , Vasodilatadores/administración & dosificaciónRESUMEN
Bronchiectasis is not as common as it once was. In developed countries, the causes include congenital disorders, cystic fibrosis, allergic bronchopulmonary aspergillosis, and immune deficiency states. Bronchiectasis can usually be diagnosed with little difficulty by supplementing complete physical examination with chest radiography, biochemical and serologic studies, and computed tomography of the lungs. Once the diagnosis is established, therapy is aimed at eradicating the underlying disease. Surgery is indicated for local lesions and for patients with massive hemoptysis or recurrent infection that is unresponsive to medical therapy.