RESUMEN
OBJECTIVE: To detect and describe medication errors and adherence to therapy in polymedicated (> 5 drugs) elderly patients (> 65 years). METHOD: A descriptive, observational study using a phone survey to polymedicated elderly outpatients. Sociodemographic, clinical, and pharmacotherapeutic data were collected, as well as information on their functional and mental capability. The number, type and severity of medication errors were measured, as was non-adherence. RESULTS: Errors were detected in 42.5% of 73 responders, with a total of 55 errors, and a mean 1.77 errors per patient. Most commonly found errors included inappropriate administration frequency and therapeutic duplicity. Regarding adherence, 43.8% were non-compliants, being sporadic in 68.8% and sequential in 31.2% of the cases. A positive relationship between error number and drug number or adherence was found. CONCLUSIONS: Actions are required from a multidisciplinary standpoint to reduce this high percentage of errors.
Asunto(s)
Errores de Medicación/estadística & datos numéricos , Polifarmacia , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Cooperación del Paciente , Encuestas y CuestionariosRESUMEN
Objetivo: Detectar y describir los errores de medicación y laadherencia al tratamiento en ancianos (> 65 años) y polimedicados(> 5 fármacos).Método: Estudio observacional, descriptivo, llevado a cabomediante cuestionario telefónico a una muestra de pacientesancianos y polimedicados no ingresados. Se recogieron datossociodemográficos y la capacidad funcional y mental, datos clínicosy farmacoterapéuticos. Se midió el número, tipo y gravedadde los errores de medicación y la adherencia.Resultados: Se detectó algún error en el 42,5% de los 73pacientes entrevistados, con un total de 55 errores, media de1,77 errores por paciente. Los errores más frecuentes fueron losde frecuencia de administración incorrecta y duplicidad terapéutica.En cuanto a la adherencia se detectó un 43,8% de incumplimiento,siendo esporádico en un 68,8% y secuencial en un31,2%. Se encontró una relación positiva entre el número deerrores y el número de medicamentos o la adherencia.Conclusiones: Es necesario, desde un punto de vista multidisciplinar,realizar actuaciones encaminadas a disminuir este altoporcentaje de errores
Objective: To detect and describe medication errors andadherence to therapy in polymedicated (> 5 drugs) elderly patients(> 65 years).Method: A descriptive, observational study using a phone surveyto polymedicated elderly outpatients. Sociodemographic, clinical,and pharmacotherapeutic data were collected, as well asinformation on their functional and mental capability. The number,type and severity of medication errors were measured, as wasnon-adherence.Results: Errors were detected in 42.5% of 73 responders, witha total of 55 errors, and a mean 1.77 errors per patient. Mostcommonly found errors included inappropriate administration frequencyand therapeutic duplicity. Regarding adherence, 43.8%were non-compliants, being sporadic in 68.8% and sequential in31.2% of the cases. A positive relationship between error numberand drug number or adherence was found.Conclusions: Actions are required from a multidisciplinarystandpoint to reduce this high percentage of errors
Asunto(s)
Masculino , Femenino , Anciano , Humanos , Utilización de Medicamentos/tendencias , Errores de Medicación/estadística & datos numéricos , Cooperación del Paciente/estadística & datos numéricos , Polifarmacia , Prescripciones de Medicamentos/estadística & datos numéricos , Epidemiología Descriptiva , Encuestas y CuestionariosRESUMEN
No disponible
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Humanos , España , Factores de Tiempo , Enfermedades Musculares , Admisión del Paciente , Complicaciones Posoperatorias , Creatina Quinasa , Hipotiroidismo , Servicio de Urgencia en HospitalRESUMEN
OBJECTIVE: Echocardiographic and Doppler analysis of myocardial mass and diastolic function in patients infected with HIV. DESIGN: Case-control study. SETTING: Tertiary referral centre, Huelva, Spain. PATIENTS: 61 asymptomatic patients with HIV infection and 32 healthy controls. MAIN OUTCOME MEASURES: Time motion, cross sectional, and Doppler echocardiographic studies were performed, and left ventricular mass and diastolic function variables determined (peak velocity of early and late mitral outflow and isovolumic relaxation time). RESULTS: Left ventricular mass index (LVMI) was decreased in patients compared with healthy controls (mean (SD): 76.7 (23.6) v 118.8 (23.5) g/m(2), p < 0.001). Linear regression analysis showed a correlation between LVMI and brachial fat and muscle areas. The ratio of peak velocities of early and late mitral outflow was decreased in HIV infected patients compared with controls (1.19 (0.44) v 1.58 (0.38), p < 0.001). This ratio was exclusively related to haemodynamic variables (heart rate, systolic and diastolic blood pressures). HIV infected patients had a prolonged isovolumic relaxation time (103.0 (10.5) v 72.9 (12.9) ms, p < 0.001). Isovolumic relaxation time was correlated only with brachial muscle area on multivariate analysis. CONCLUSIONS: HIV infected patients had a reduced left ventricular mass index and diastolic functional abnormalities. These cardiac abnormalities are predominantly related to nutritional status.
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Infecciones por VIH/patología , Infecciones por VIH/fisiopatología , Miocardio/patología , Adulto , Antropometría , Fármacos Anti-VIH/uso terapéutico , Estudios de Casos y Controles , Diástole , Ecocardiografía , Infecciones por VIH/complicaciones , Ventrículos Cardíacos/patología , Humanos , Masculino , Trastornos Nutricionales/patología , Trastornos Nutricionales/fisiopatología , Trastornos Nutricionales/virología , Estado Nutricional , Tamaño de los Órganos , Estudios ProspectivosRESUMEN
No disponible