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1.
Rep Pract Oncol Radiother ; 29(3): 340-347, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39144273

RESUMEN

Background: The GI Tumors Workgroup, a division of the Spanish Society of Radiation Therapy, conducted a survey in December 2020 to assess the adherence of radiation oncologists in Spain to international guidelines for gastrointestinal tumors. Materials and methods: Using Google Forms, we designed a survey covering treatments for esophageal, gastric, pancreatic, and rectal cancers. Results: In esophageal cancer treatment, neoadjuvant chemoradiation was the standard in 76.7% of institutions. Radiation doses range from 41.1 to 50.4 Gy in conventional fractionation. Planning positron emission tomography-computed tomography (PET-CT) was performed in 83.3% of centers, and intensity-modulated radiation therapy/volumetric-arc radiation therapy (IMRT/VMAT) was the preferred technique in 86.7% of institutions. For gastric cancer, 71.4% followed perioperative chemotherapy guidelines. In the case of adjuvant radiotherapy, the majority prescribed 45-50.4 Gy, and 82.1% used IMRT/VMAT for treatment. For pancreas cancer, neoadjuvant chemotherapy followed by surgery in borderline resectable tumors and induction chemotherapy followed by radical radiotherapy for non-resectable tumors were the most frequent approaches. IMRT/VMAT was the primary technique. Locally advanced rectal cancer treatment is mainly based on neoadjuvant radiotherapy in all institutions. The preferred radiation doses typically range from 45 to 50 Gy in conventional fractionation. IMRT/VMAT was standard in most Institutions. Conclusions: Spain's radiotherapy practices among respondents generally align with international guidelines for GI tumors highlighting Spain's commitment to evidence-based medical practice.

2.
Clin Transl Oncol ; 12(8): 554-61, 2010 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-20709653

RESUMEN

Radiation therapy in combination with other treatments, such as surgery and chemotherapy, increases locoregional control and survival in patients with thoracic, abdominal and pelvic malignancies. Nevertheless, significant clinical toxicity with combined treatments may be seen in these patients. With the advent of tridimensional conformal radiotherapy (3D-CRT), dose-volume histograms (DVH) can be generated to assess the dose received by the organs at risk. The possible relationship between these parameters and clinical, anatomical and, more recently, genetic factors has to be considered. Treatment options include initial conservative medical therapies, endoscopic procedures, hyperbaric oxygen and surgery. Some pharmacological agents to prevent gastrointestinal toxicity are under investigation.


Asunto(s)
Enfermedades Gastrointestinales/etiología , Neoplasias/radioterapia , Traumatismos por Radiación/etiología , Animales , Enteritis/etiología , Enteritis/patología , Enteritis/terapia , Esofagitis/etiología , Esofagitis/patología , Esofagitis/terapia , Enfermedades Gastrointestinales/patología , Enfermedades Gastrointestinales/terapia , Humanos , Proctitis/etiología , Proctitis/patología , Proctitis/terapia , Traumatismos por Radiación/patología , Traumatismos por Radiación/terapia , Radiación Ionizante , Protectores contra Radiación/uso terapéutico , Radioterapia/efectos adversos , Dosificación Radioterapéutica , Ratas , Factores de Riesgo
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