RESUMEN
Variations of serum zinc and copper in relation with iron absorption, in a group of dogs undergoing pancreatic duct ligation, have been studied. Mean plasma iron concentrations, total serum zinc and copper were determined after administration of an iron dose (60 mg FeSO4 . 4H2O, pH 4). Significant increase of serum zinc and plasma iron was observed. In copper experiments no significant results were found.
Asunto(s)
Compuestos Ferrosos/administración & dosificación , Hierro/administración & dosificación , Páncreas/fisiología , Zinc/sangre , Animales , Cobre/sangre , Perros , Hierro/sangre , Conductos PancreáticosRESUMEN
This study deals with the effects of iron overloading on total iron-binding capacity TIBC) in fasting subjects. Overloading was obtained by oral administration of 198 mg. ferrous gluconate. The method of Bothwell and Mallet was used for plasma iron determination; the Mg CO3 methods was used for TIBC. It was that normal subjects as well as hyperthyroid, hypothyroid goiter patients showed an increase of TIBC under these conditions. These results could be explained either on the basis of functional heterogeneity of transferrin bound iron, or of a new protein.