RESUMEN
Activity of AChE in separate cells of the neural tube and ganglionic plate (neural crest) is detected histochemically in chick embryos after 36, 48, 60 and 74 h of incubation, before any specific morphological signs characteristic for the neuroblast appear in them. It is stated that biochemical determination, formation of acetylcholine system coinsides with the proneuroblast phase. The product of the reaction for AChE is a marker which helps to observe migration of proneuroblasts in embryos at early stages of development.
Asunto(s)
Acetilcolinesterasa/metabolismo , Embrión de Pollo/enzimología , Sistema Nervioso/embriología , Neuronas/enzimología , Animales , Movimiento Celular , Factores de TiempoRESUMEN
Clinico-experimental study of the pentoxyl and methyluracil effect upon the natural resistance in mitral stenosis cases is presented together with the findings obtained in the experiments dealing with the healing of the wounds infected with pathogenic staphylococcus. All the control animals developed subcutaneous abscesses leading to the separation of the wound margins. The inflammation of the wound was less pronounced in the animals treated with pentoxyl and methyluracil. The use of pyrimidin derivatives before and during operation and postoperatively resulted in the decrease of the incidence of postoperative suppurative complications.
Asunto(s)
Estenosis de la Válvula Mitral/cirugía , Infección de la Herida Quirúrgica/prevención & control , Uracilo/análogos & derivados , Adolescente , Adulto , Animales , Evaluación de Medicamentos , Humanos , Persona de Mediana Edad , Cuidados Posoperatorios , Cuidados Preoperatorios , Conejos , Uracilo/uso terapéuticoRESUMEN
A high intensity of the reactions to lactate dehydrogenase and glucous-6-phosphate dehydrogenase was demonstrated histochemically in the neural anlage of the chick embryos after 15, 20, 24, 30, 44, 48 and 72 hours of incubation. At early stages of the development cranio-caudal gradient of enzymatic reactions was distinctly traced. A high intensity of the reactions was observed in certain cells of the neural groove in 24-hours' embryos and in the neural tube of 48-hours' embryos. These cells are supposed to develop into neuroblasts.
Asunto(s)
Embrión de Pollo/citología , Glucosafosfato Deshidrogenasa/metabolismo , L-Lactato Deshidrogenasa/metabolismo , Neuronas/enzimología , Animales , Histocitoquímica , Neuroglía/enzimologíaRESUMEN
The effect of retabolil on experimental liver cirrhosis in rats was studied. The results of the treatment point to a beneficial action of retabolil on the course of this malady, which found its expression in the prevalence regeneration manifestations over the processes of degeneration, as well as in the inhibitory effect on the development of liver cirrhosis. From morphometric investigations it follows that for retabolil the structure-target is the nucleonic system of the cells, largely of hepatocytes.
Asunto(s)
Anabolizantes/uso terapéutico , Cirrosis Hepática/tratamiento farmacológico , Nandrolona/análogos & derivados , Animales , Tetracloruro de Carbono/efectos adversos , Núcleo Celular/efectos de los fármacos , Decanoatos/uso terapéutico , Hígado/efectos de los fármacos , Hígado/patología , Cirrosis Hepática/inducido químicamente , Regeneración Hepática , Masculino , Nandrolona/uso terapéutico , RatasRESUMEN
Heteroperitoneum was employed with hemostatic purposes for splenic injuries, Experiments were conducted on 80 dogs. The results of studies have evidenced the development of aseptic inflammation at the site of a contact between the spleen and a graft. The proper splenic capsule and omentum are the source of development of new connective tissues. Gradually, heteroperitoneum is subject to fibrillolysis, fragmentation and fusion. Six-seven months following the operation heteroperitoneum is completely substituted by newly-formed connective tissues. A newly-formed capsule is considerably thicker than the proper splenic capsule, and its structure differs but little from the latter. One case of clinical application of the heterogenous preserved peritoneum with hemostatic purposes in splenic trauma is described.