RESUMEN

Hb J-Cordoba [alpha 2A beta 2(95)(FG2)Lys----Met], is one of the few hemoglobin variants discovered in Argentina. The structure and functional abnormalities are described. Hb J-Cordoba exhibits a slightly increased oxygen affinity, low cooperativity, and normal interaction with heterotropic cofactors.

Asunto(s)

Aminoácidos/análisis , Hemoglobina J/análisis , Hemoglobinas Anormales/análisis , Argentina , Electroforesis de las Proteínas Sanguíneas , Femenino , Humanos , Lactante , Oxígeno/sangre , Solubilidad