RESUMEN

Counterfeiting drugs has been a global concern for years. Considering the lack of transparency within the current pharmaceutical distribution system, research has shown that blockchain technology is a promising solution for an improved supply chain system. This study aims to explore the current solution proposals for distribution systems using blockchain technology. Based on a literature review on currently proposed solutions, it is identified that the secrecy of the data within the system and nodes' reputation in decision making has not been considered. The proposed prototype uses a zero-knowledge proof protocol to ensure the integrity of the distributed data. It uses the Markov model to track each node's 'reputation score' based on their interactions to predict the reliability of the nodes in consensus decision making. Analysis of the prototype demonstrates a reliable method in decision making, which concludes with overall improvements in the system's confidentiality, integrity, and availability. The result indicates that the decision protocol must be significantly considered in a reliable distribution system. It is recommended that the pharmaceutical distribution systems adopt a relevant protocol to design their blockchain solution. Continuous research is required further to increase performance and reliability within blockchain distribution systems.

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RESUMEN

The World Health Organization (WHO) in 2016 considered m-health as: "the use of mobile wireless technologies including smart devices such as smartphones and smartwatches for public health". WHO emphasizes the potential of this technology to increase its use in accessing health information and services as well as promoting positive changes in health behaviours and overall management of diseases. In this regard, the capability of smartphones and smartwatches for m-health monitoring through the collection of patient data remotely, has become an important component in m-health system. It is important that the integrity of the data collected is verified continuously through data authentication before storage. In this research work, we extracted heart rate variability (HRV) and decomposed the signals into sub-bands of detail and approximation coefficients. A comparison analysis is done after the classification of the extracted features to select the best sub-bands. An architectural framework and a used case for m-health data authentication is carried out using two sub-bands with the best performance from the HRV decomposition using 30 subjects' data. The best sub-band achieved an equal error rate (EER) of 12.42%.

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RESUMEN

With the widespread use of embedded sensing capabilities of mobile devices, there has been unprecedented development of context-aware solutions. This allows the proliferation of various intelligent applications, such as those for remote health and lifestyle monitoring, intelligent personalized services, etc. However, activity context recognition based on multivariate time series signals obtained from mobile devices in unconstrained conditions is naturally prone to imbalance class problems. This means that recognition models tend to predict classes with the majority number of samples whilst ignoring classes with the least number of samples, resulting in poor generalization. To address this problem, we propose augmentation of the time series signals from inertial sensors with signals from ambient sensing to train Deep Convolutional Neural Network (DCNNs) models. DCNNs provide the characteristics that capture local dependency and scale invariance of these combined sensor signals. Consequently, we developed a DCNN model using only inertial sensor signals and then developed another model that combined signals from both inertial and ambient sensors aiming to investigate the class imbalance problem by improving the performance of the recognition model. Evaluation and analysis of the proposed system using data with imbalanced classes show that the system achieved better recognition accuracy when data from inertial sensors are combined with those from ambient sensors, such as environmental noise level and illumination, with an overall improvement of 5.3% accuracy.