Asunto(s)
Control de Infecciones , Tamizaje Masivo , Viaje , Infección por el Virus Zika/complicaciones , Infección por el Virus Zika/diagnóstico , Virus Zika/aislamiento & purificación , Artralgia/virología , Conjuntivitis/virología , Exantema/virología , Fatiga/virología , Femenino , Fiebre/virología , Guyana Francesa/epidemiología , Cefalea/virología , Humanos , Control de Infecciones/métodos , Masculino , Mialgia/virología , Estudios Prospectivos , Prurito/virología , Suriname , Virus Zika/genética , Infección por el Virus Zika/epidemiología , Infección por el Virus Zika/transmisiónRESUMEN
Following of the emergence of Zika virus in Brazil in 2015, an epidemiological surveillance system was quickly implemented in the French overseas Territories of America (FTA) according to previous experience with dengue and chikungunya and has detected first cases of Zika. General practitioners and medical microbiologists were invited to report all clinically suspected cases of Zika, laboratory investigations were systematically conducted (RT-PCR). On 18 December, the first autochthonous case of Zika virus infection was confirmed by RT-PCR on French Guiana and Martinique, indicating introduction of Zika virus in FTA. The viral circulation of Zika virus was then also confirmed on Guadeloupe and Saint-Martin. We report here early findings on 203 confirmed cases of Zika virus infection identified by RT-PCR or seroneutralisation on Martinique Island between 24 November 2015 and 20 January 2016. All cases were investigated. Common clinical signs were observed (maculopapular rash, arthralgia, fever, myalgia and conjunctival hyperaemia) among these patients, but the rash, the foundation of our case definition, may be absent in a significant proportion of patients (16%). These results are important for the implementation of a suspected case definition, the main tool for epidemiological surveillance, in territories that may be affected by ZIKV emergence, including Europe.
Asunto(s)
Enfermedades Transmisibles Emergentes/epidemiología , Brotes de Enfermedades , Vigilancia de la Población , Infección por el Virus Zika/diagnóstico , Infección por el Virus Zika/epidemiología , Virus Zika/aislamiento & purificación , Humanos , Martinica/epidemiología , ARN Viral/genética , ARN Viral/aislamiento & purificación , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Análisis de Secuencia de ADN , Virus Zika/genética , Infección por el Virus Zika/transmisiónRESUMEN
The current Zika virus outbreak and its potential severe health consequences, especially congenital fetal syndrome, have led to increased concern about sexual transmission, especially in pregnant women and women of reproductive age. Here we report a case of Zika virus sexual transmission, likely male-to-female, in a totally asymptomatic couple.
Asunto(s)
Enfermedades Asintomáticas , Enfermedades Virales de Transmisión Sexual/diagnóstico , Enfermedades Virales de Transmisión Sexual/virología , Viaje , Infección por el Virus Zika/diagnóstico , Infección por el Virus Zika/virología , Adulto , Femenino , Francia , Humanos , Masculino , MartinicaRESUMEN
We report three unrelated cases of Zika virus infection in patients returning from Martinique, Brazil and Colombia respectively, to Montpellier, France. They developed symptoms compatible with a mosquito-borne disease, and serological and molecular investigations indicated a recent Zika virus infection. Considering the recent warning for the likely teratogenicity of Zika virus and the presence of competent mosquito vectors in southern France, these cases highlight the need for awareness of physicians and laboratories in Europe.