Asunto(s)
Ácido Úrico/sangre , Adolescente , Factores de Edad , Niño , Preescolar , Creatinina/sangre , Alemania Oriental , Humanos , Valores de Referencia , Factores SexualesRESUMEN
The result of our examinations was that there is a vast correspondence of the medium levels of serum uric acid as well as of the frequency of hyperuricaemia between children after the 10th year of age and the adults. In comparison to the average population children from families with a gout anamnesis revealed a twice as frequent disturbance of the purine metabolism. In a familial appearance of gout and/or in unclear renal as well as joint findings the paediatrician should think of the presence of a disturbance of the purine metabolism.
Asunto(s)
Gota/genética , Errores Innatos del Metabolismo de la Purina-Pirimidina/genética , Purinas/sangre , Ácido Úrico/sangre , Adolescente , Adulto , Niño , Preescolar , Colesterol/sangre , Femenino , Tasa de Filtración Glomerular , Gota/sangre , Humanos , Enfermedades Renales/sangre , Enfermedades Renales/genética , Pruebas de Función Renal , Masculino , Fenotipo , Errores Innatos del Metabolismo de la Purina-Pirimidina/sangre , Factores Sexuales , Triglicéridos/sangreRESUMEN
All living children suffering from myelomeningoceles and being 1 to 12 years old were registered by means of a questionnaire. The death certificates of all those children who came to death from myelomeningoceles between 1973 and 1977 were also evaluated. Ratio of morbidity: 6 to 10000 live born children. In the first year of life the mortality rate amounted to 34%.