RESUMEN
BACKGROUND: This study was performed to assess radiotherapy education among family physicians. METHODS: A questionnaire evaluating radiotherapy training and knowledge was given to participants of a palliative care conference. RESULTS: Thirty-four physicians completed the survey (71% response rate). Major deficiencies in radiotherapy education were identified and 88% of respondents stated that they did not have adequate knowledge. Only 33% had received formal training in radiotherapy and the majority (77%) thought that they would benefit considerably from continuing medical education. CONCLUSIONS: Better education about radiotherapy is required for family physicians and could lead to increased patient referral for such treatment.
Asunto(s)
Internado y Residencia , Médicos de Familia/educación , Radioterapia , Adulto , Educación Médica Continua/organización & administración , Evaluación Educacional/estadística & datos numéricos , Femenino , Humanos , Masculino , Ontario , Encuestas y CuestionariosAsunto(s)
Anticuerpos/análisis , Antígenos de Plaqueta Humana , Antígenos HLA/inmunología , Enfermedades del Sistema Inmune/etiología , Enfermedades del Recién Nacido/etiología , Trombocitopenia/etiología , Adulto , Suero Antilinfocítico/análisis , Antígenos de Grupos Sanguíneos , Padre , Femenino , Técnica del Anticuerpo Fluorescente , Antígenos HLA/clasificación , Humanos , Recién Nacido , Integrina beta3 , Isoantígenos/análisis , MadresRESUMEN
This study was undertaken to document the incidence of immediate, nonhemolytic transfusion reactions and to identify a technique or set of techniques that would best identify the different causes of these reactions. A variety of tests were employed to detect lymphocyte, granulocyte, platelet and anti-IgA antibodies. During this study 26,318 units of blood components were transfused on 5,030 occasions. 191 immediate, nonhemolytic reactions were experienced giving an incidence per unit of 0.73%. Blood specimens from 101 of these patients were investigated along with serum from 57 patients who showed no reaction to transfusion as controls. We show that standard B cell lymphocytotoxicity testing is the technique with which most antibodies can be detected (64% of reactors positive vs. 30% of controls, p less than 0.001). Additional tests did not significantly increase the level of antibody detection.
Asunto(s)
Reacción a la Transfusión , Anticuerpos Antiidiotipos/aislamiento & purificación , Plaquetas/inmunología , Pruebas Inmunológicas de Citotoxicidad , Femenino , Granulocitos/inmunología , Antígenos HLA/inmunología , Humanos , Inmunoglobulina A/inmunología , Isoanticuerpos/aislamiento & purificación , Linfocitos/inmunología , MasculinoRESUMEN
Two cases of neonatal alloimmune thrombocytopenia are presented. Using the indirect immunofluorescence test on platelets in suspension, the presence of non-agglutinating platelet specific antibodies with the specificity anti-Zwa could be demonstrated. In both cases diagnosis of alloimmunization was made before delivery of a second child, typing of the family was done and recommendations could be made concerning clinical management. Compatibility testing between the mother's serum and donor platelets (Zwa-negative) was predictable of a normal transfused platelet survival in the newborn.