RESUMEN
This paper presents data on the detection of hantavirus in the excretory organs of Apodemus mice which are natural carriers of pathogenic hantaviral serotypes in the Primorye Region. Acute infection periods were detected in naturally infected rodents with the highest hantavirus dissemination to the environment in different phases of rodent population cycles. There was a relationship between the rise of morbidity and the seasonal manifestation of hemorrhagic fever with renal syndrome morbidity and activity of hantavirus reproduction in the murine excretory organs.
Asunto(s)
Reservorios de Enfermedades/virología , Fiebre Hemorrágica con Síndrome Renal/epidemiología , Fiebre Hemorrágica con Síndrome Renal/veterinaria , Murinae/virología , Orthohantavirus/aislamiento & purificación , Animales , Fiebre Hemorrágica con Síndrome Renal/virología , Intestinos/virología , Densidad de Población , Glándulas Salivales/virología , Estaciones del Año , Siberia/epidemiología , Vejiga Urinaria/virologíaRESUMEN
The paper presents the results of studying the time course of changes in antibodies of varying avidity in murine rodents. The presence of low-avidity antibodies is shown to reflect the status of acute infection in the rodent population and their active viral shedding. A relationship is shown between the detection of low-avidity antibodies in animals in spring and autumn and the rise of endemic hemorrhagic fever (EHF) morbidity. The findings demonstrate it possible to use data on the determination of antibodies of varying avidity in the population of murine rodents for the assessment of epizootic and epidemic processes.