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1.
Ann Saudi Med ; 19(4): 304-7, 1999.
Artículo en Inglés | MEDLINE | ID: mdl-17277529

RESUMEN

BACKGROUND: Non-insulin dependent diabetes mellitus (type II DM) is frequently associated with abnormal levels of lipids, particularly in patients with poor diabetic control. This study was designed to investigate the influence of type II DM on levels of plasma lipids and other related parameters in Saudi patients. Saudi Arabia has a high prevalence of diabetes mellitus in the adult population. Since the Saudi population presents a unique group with different dietary habits, lifestyle and genetic make-up, we investigated the lipids, lipoprotein and apolipoprotein pattern in Saudi type II DM patients. MATERIALS AND METHODS: This study was conducted on 2835 diabetic patients (1361 males, 1474 females) and 200 age-matched healthy adults from the same areas with no history of diabetes mellitus. Data collected included height, weight, body mass index (BMI), blood pressure and other relevant parameters. Lipids, lipoproteins and apolipoproteins were estimated, and correlation studies were carried out between these parameters. Lipids, lipoproteins and apolipoproteins were also correlated with the fasting blood glucose. RESULTS: Our results showed significant elevation in cholesterol and triglyceride, apo A and apo B levels in the diabetic males and females compared to the controls. Approximately 37% of the total DM patients fell in the borderline risk group, while 28.4% fell in the high-risk group for development of cardiovascular disease. Lipoproteins did not differ significantly. Cholesterol, triglyceride, VLDL, LDL and Hb A1c correlated positively with glucose (P<0.05), while triglyceride, VLDL, HDL, LDL, apo A and apo B showed significant correlation with cholesterol, where all parameters increased with cholesterol except HDL, which decreased as cholesterol increased. CONCLUSION: The findings point toward high prevalence of dyslipidemia in type II DM Saudi patients.

3.
Ann Saudi Med ; 14(6): 495-8, 1994 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-17587957

RESUMEN

Body mass index (BMI) is generally accepted as a useful index of various clinical situations related to obesity. However, there are no reference BMI charts for Saudi children; this paper is an attempt to establish these. A total of 21,638 Saudi schoolchildren between ages six to 16 years (49.6% males) were studied. Curves for BMI, seven percentiles - 5th, 10th, 25th, 50th, 75th, 90th and 95th - were constructed. As a reference material, BMI data for American children were modified into Hegira years. It was found that, in agreement with others, the BMI for the Saudi children studied was age- and gender-dependent. Comparison between Saudi data and international reference showed the expected genetic influence. These results remain to be compared with those from other regions in the Kingdom.

4.
Ann Saudi Med ; 13(6): 541-6, 1993 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-17589093

RESUMEN

This prospective study analyzes the clinical features and histopathological findings in liver biopsies of pediatric patients presenting to the hospital with liver disease during a 10 year period. Only those patients in whom liver biopsy was performed for a tissue diagnosis were included. Fifty patients were investigated, all below the age of 12 years, of whom 36 were male and 14 female. Thirty-two were of neonatal-infantile group, 11 had a diagnosis of neonatal giant cell he hepatitis of infections origin and an intact biliary tree. Two had septic shock and one had leishmaniasis. The remaining 18 patients of the neonatal-infantile group constituted five case of glycogen storage disease, six of infantile obstructive cholangiopathy (biliary atreasia), four of fatty change and one each of congenital hepatic fibrosis, neuroblastoma and nonspecific reactive hepatitis. The eighteen older children had the following diagnoses: thalassemia in five, sickle cell disease in four, two each of Reye syndrome and hepatoblastoma. The remaining were one each of glycogen storage disease, Rotor syndrome, cirrhosis, fatty change and non-Hodgkin lymphoma (NHL). These findings are presented and discussed.

5.
Am J Hematol ; 43(1): 54-6, 1993 May.
Artículo en Inglés | MEDLINE | ID: mdl-8317464

RESUMEN

This paper describes the case of a female child who presented with severe thrombocytopenia and Cushing's syndrome. The underlying cause was found to be an adrenal cortical adenoma, removal of which was followed by complete recovery of both conditions. The pathogenesis of both presenting features in relation to the adrenal tumor is discussed.


Asunto(s)
Adenoma/complicaciones , Neoplasias de la Corteza Suprarrenal/complicaciones , Síndrome de Cushing/complicaciones , Púrpura Trombocitopénica/etiología , Adenoma/diagnóstico , Adenoma/patología , Adenoma/cirugía , Corticoesteroides/sangre , Neoplasias de la Corteza Suprarrenal/diagnóstico , Neoplasias de la Corteza Suprarrenal/patología , Neoplasias de la Corteza Suprarrenal/cirugía , Adrenalectomía , Síndrome de Cushing/sangre , Síndrome de Cushing/patología , Femenino , Estudios de Seguimiento , Humanos , Lactante , Recuento de Plaquetas , Púrpura Trombocitopénica/sangre , Púrpura Trombocitopénica/patología , Factores de Tiempo
6.
Cancer Detect Prev ; 9(3-4): 215-8, 1986.
Artículo en Inglés | MEDLINE | ID: mdl-3742501

RESUMEN

The purpose of this retrospective clinical study is to look into the etiological role of alshammah and alqat consumption in the causation of squamous cell carcinoma of the head and neck (SCHN) in Arabia. Alshammah and alqat are traditional forms of chewable tobacco very commonly used in southern Saudi Arabia and Yemem. In a 2 year period 64 patients with histologically proven SCHN were found. Most of them were originally from southern Saudi Arabia and Yemen. Of these 64 patients 52 (81%) admitted alshammah consumption. Of these 52 patients 22 admitted alqat consumption in addition. Thirty-eight (59%) had oral cancer, while the rest had pharyngeal and laryngeal cancer. All the 38 patients with oral cancer either used alshammah alone (16 patients) or used both alshammah and alqat (22 patients). The median duration of alshammah consumption was 15 years and that of alqat was 12 years. Alcohol was not consumed among the group and only few were cigarette smokers. Most patients presented in the late stage of the disease. The evidence implicating alshammah and alqat in the causation of SCHN is only clinically based. Further controlled prospective clinical and experimental studies are needed to confirm the theory.


Asunto(s)
Carcinoma de Células Escamosas/etiología , Neoplasias de la Boca/etiología , Nicotiana , Plantas Tóxicas , Tabaco sin Humo , Carcinoma de Células Escamosas/epidemiología , Neoplasias de Cabeza y Cuello/epidemiología , Neoplasias de Cabeza y Cuello/etiología , Humanos , Neoplasias de la Boca/epidemiología , Estudios Retrospectivos , Arabia Saudita
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