RESUMEN
A new donor antidiphtheritic immunoglobulin produced in the Hematology and Transfusiology Institute of AMS of Ukraine and Donetsk transfusiology station is discussed in the article. The medication, antidiphtheritic horse serum had been used during the diphtheria epidemic, as a medication in Donetsk clinics. The medication meets requirements of State and International Standards and is registered in Ukraine.
Asunto(s)
Antitoxina Diftérica/uso terapéutico , Difteria/tratamiento farmacológico , Sueros Inmunes/inmunología , Inmunoglobulinas/uso terapéutico , Animales , Donantes de Sangre , Difteria/inmunología , Antitoxina Diftérica/administración & dosificación , Caballos , Humanos , Sueros Inmunes/administración & dosificación , Inmunoglobulinas/administración & dosificación , Inyecciones Intramusculares , UcraniaAsunto(s)
Anticuerpos Antibacterianos/biosíntesis , Donantes de Sangre , Antígenos HLA/inmunología , Inmunización , Infecciones Estafilocócicas/inmunología , Toxoide Estafilocócico/inmunología , Staphylococcus/inmunología , Adulto , Factores de Edad , Anticuerpos Antibacterianos/inmunología , Femenino , Humanos , Masculino , Clase Social , Infecciones Estafilocócicas/prevención & control , Toxoide Estafilocócico/administración & dosificaciónRESUMEN
It is concluded that the outcome of hemotransfusion complication is influenced by the clinical state of the patients during incompatible transfusion, the amount of the transfused medium as well as the treatment carried out after development of acute renal failure. Constant alertness during transfusion as well as wider use of blood antigen-typed for Rh-Hr system antigens are of major importance for the prophylaxis of blood transfusion complications.
Asunto(s)
Reacción a la Transfusión , Tipificación y Pruebas Cruzadas Sanguíneas , Transfusión Sanguínea/estadística & datos numéricos , Humanos , Mortalidad , UcraniaRESUMEN
Blood groups, including rhesus grouping, have been determined in 218 donors and HLA of loci A, B, C in 121 donors immunized with adsorbed tetanus toxoid (40 binding units). The presence of HLA Aw 32, B 8; HLA Bw 16, haplotypes A3 Bw 16 and A1, blank antigens of locus C is linked with the production of, respectively, high or low (less than or equal to 16 I.U./ml) antibody titers. The effectiveness of immunization is influenced by agglutinogen B, which is confirmed by its associations (in a complex with HLA Bw 16 or Bw 35) with low immune response.