RESUMEN
Higher fatty acids of low- and high-density lipoprotein lipids are analyzed by gas chromatography in patients with chronic diseases of the liver (chronic cholecystitis, cholelithiasis, chronic hepatitis, and cirrhosis of the liver). The results recommend the fatty acid composition of serum lipoprotein lipids as an informative characteristic in evaluation of lipid metabolism disorders in the liver.
Asunto(s)
Ácidos Grasos/sangre , Lipoproteínas/sangre , Hepatopatías/sangre , Adulto , Cromatografía de Gases/estadística & datos numéricos , Enfermedad Crónica , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Condition was studied of the microcirculatory bed in 80 patients with chronic noncalculous cholecystitis and 38 patients with calculous cholecystitis with the aid of biomicroscopy of bulbar conjunctiva and histological examination of removed gallbladders. Changes in microcirculation were characterized by enhancement of arteriole-venous shunting, diminution of the number of the functioning capillaries, appearance of signs of venous congestion, lowering of microvessel reactivity in an acute nitroglycerin test, which fact may suggest their systemic character.
Asunto(s)
Colecistitis/fisiopatología , Colelitiasis/fisiopatología , Conjuntiva/irrigación sanguínea , Adulto , Enfermedad Crónica , Conjuntiva/efectos de los fármacos , Vesícula Biliar/irrigación sanguínea , Humanos , Microcirculación/efectos de los fármacos , Microcirculación/fisiopatología , Nitroglicerina , VasodilatadoresRESUMEN
Fatty-acid composition of lipids was studied by gas chromatography techniques as was the level of free cholesterol in high- and low-density lipoproteins in 15 patients with chronic hepatitis and 15 hepatocirrhotic patients. Significant changes in fatty-acid spectrum were recordable suggesting activation of the process of lipid peroxidation. The above changes were at their greatest in patients with hepatocirrhosis.
Asunto(s)
Ácidos Grasos/sangre , Hepatitis Crónica/sangre , Lipoproteínas HDL/sangre , Lipoproteínas LDL/sangre , Cirrosis Hepática/sangre , Adulto , Cromatografía de Gases , Humanos , Persona de Mediana EdadRESUMEN
The authors studied the cardiac rhythm regulation status in 22 patients with chronic noncalculous cholecystitis, 35 patients with chronic calculous cholecystitis and 31 patients with chronic hepatitis. All the patients showed signs of sympathicotonic type of regulation of cardiac rhythm. Upon receiving propranolol (0.04), 67.8% of patients displayed no vegetative regulation, with 3.2% cases demonstrating a paradoxical trend of vegetative reactions.
Asunto(s)
Sistema Nervioso Autónomo/fisiopatología , Sistema Cardiovascular/fisiopatología , Colecistitis/fisiopatología , Hepatitis Crónica/fisiopatología , Adulto , Sistema Nervioso Autónomo/efectos de los fármacos , Sistema Cardiovascular/efectos de los fármacos , Colelitiasis/fisiopatología , Enfermedad Crónica , Femenino , Humanos , Masculino , Propranolol , SimpaticolíticosRESUMEN
As many as 163 young male patients with chronic noncalculous cholecystitis were studied for motility of the biliary tract. Normal findings were in 15.9% of cases. Hypocontractility of the gallbladder, hypermyotonia of the Oddi sphincter (with 33.7% and 44.2% respectively), and concurrent presence thereof were the most commonly seen types of dyskinesia. The results obtained suggest that the above abnormalities in motility of the biliary tract may have a part in the origination and/or progression of chronic cholecystitis.
Asunto(s)
Colecistitis/fisiopatología , Vaciamiento Vesicular , Tono Muscular , Esfínter de la Ampolla Hepatopancreática/fisiopatología , Adolescente , Adulto , Discinesia Biliar/diagnóstico por imagen , Discinesia Biliar/fisiopatología , Colecistitis/diagnóstico por imagen , Enfermedad Crónica , Diagnóstico Diferencial , Vesícula Biliar/diagnóstico por imagen , Humanos , Masculino , Esfínter de la Ampolla Hepatopancreática/diagnóstico por imagen , UltrasonografíaRESUMEN
As many as 42 patients with chronic noncalculous cholecystitis who ranged from 18 to 36 years old were studied for the left ventricular systolic-and-diastolic function and for humoral immunity. Signs of left ventricular diastolic dysfunction were revealed as were increased levels of complement-fixing antibodies to the tissues of the gallbladder and myocardium. It is suggested that one of the pathogenetic mechanisms of the abnormal changes in the cardiac muscle might be immune factors for there is a similarity between antigenic determinants of the gallbladder and myocardium tissues antigen.