Asunto(s)
Anticuerpos Anticitoplasma de Neutrófilos/sangre , Síndromes Compartimentales/complicaciones , Ciclofosfamida/administración & dosificación , Glomerulonefritis , Glucocorticoides/administración & dosificación , Granulomatosis con Poliangitis , Paraparesia , Enfermedades de las Parótidas , Glándula Parótida/patología , Prednisona/administración & dosificación , Diálisis Renal/métodos , Rabdomiólisis , Humanos , MasculinoAsunto(s)
Calcinosis/diagnóstico por imagen , Endocardio/diagnóstico por imagen , Fibrosis Endomiocárdica/complicaciones , Derrame Pericárdico/etiología , Adulto , Calcinosis/etiología , Fibrosis Endomiocárdica/diagnóstico por imagen , Humanos , Derrame Pericárdico/diagnóstico por imagen , RadiografíaAsunto(s)
Plasmodium/clasificación , África Austral/epidemiología , Animales , Humanos , Malaria/epidemiologíaRESUMEN
A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum acid phosphatase and prostatic-specific antigen (PSA) were normal. Serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D were just below the normal limit and parathyroid hormone was moderately elevated. A transiliac bone biopsy specimen revealed expanded bone trabeculae, abundance of osteoid-covered surfaces, and heavy metastatic spread. To the best of our knowledge, this is the first description of the association of osteosclerosis and metastatic transitional-cell carcinoma of the bladder.
Asunto(s)
Huesos/patología , Carcinoma de Células Transicionales/patología , Osteosclerosis/patología , Osteosclerosis/fisiopatología , Neoplasias de la Vejiga Urinaria/patología , Humanos , Masculino , Persona de Mediana Edad , Metástasis de la Neoplasia , Osteosclerosis/diagnóstico por imagen , RadiografíaAsunto(s)
Enfermedad de Alzheimer/diagnóstico , Articulaciones/fisiopatología , Examen Físico , Anciano , Femenino , HumanosRESUMEN
An Ethiopian immigrated to Israel and gave a positive test result for human immunodeficiency virus. Soon after, he was thrice admitted to hospital in 3 months for severe pneumonia. Acquired immunodeficiency syndrome was diagnosed, as was hyperreactive malarial splenomegaly (HMS). Thereafter, during maintained proguanil treatment for HMS, the patient remained well for 16 months. Then, after another pneumonic illness, pneumococcal vaccine was administered. Proguanil was maintained for another 10 months and, despite declining CD4 cell counts, good health continued for a further 18 months.
Asunto(s)
Antimaláricos/uso terapéutico , Infecciones por VIH/complicaciones , Malaria/tratamiento farmacológico , Neumonía/prevención & control , Proguanil/uso terapéutico , Esplenomegalia/tratamiento farmacológico , Humanos , Malaria/complicaciones , Masculino , Persona de Mediana Edad , Esplenomegalia/complicacionesRESUMEN
A case-control study was performed to evaluate factors associated with successful rehabilitation in elderly patients who sustained hip fractures. All 170 patients with fractured hips hospitalized in the geriatrics ward of the Soroka Medical Center in Beer-Sheva, Israel between 1987 and 1991 were studied. Success of rehabilitation was determined by staff evaluation of the patient's ability to walk and perform activities of daily living. The independent variables, including sociodemographic and medical variables, and mental and functional assessments, were assessed by chart reviews, staff evaluation and mental tests. One-hundred and twenty-nine patients (75.9%) were successfully rehabilitated. A normal mental state (p < 0.0001), female gender (p < 0.02) and absence of diabetes mellitus (p < 0.008) were associated significantly with successful rehabilitation.