1.
Journal of Zhejiang University. Medical sciences
; (6): 208-214, 2009.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-310365
RESUMEN
Distant metastasis is the main cause of cancer death. Tetraspanins (transmembrane 4 superfamily, TM4SF) is capable of forming transmembrane complexes with integrin family participating in cell adhesion, migration and tumor metastasis. This review elucidates the structure of tetraspanins and its function in regulating metastasis as form of multimolecular transmembrane complexes with integrin.