Asunto(s)
Hiperpigmentación/inducido químicamente , Queloide/complicaciones , Piel/patología , Triamcinolona Acetonida/efectos adversos , Diagnóstico Diferencial , Femenino , Glucocorticoides/administración & dosificación , Glucocorticoides/efectos adversos , Humanos , Hiperpigmentación/patología , Inyecciones Intralesiones , Queloide/tratamiento farmacológico , Índice de Severidad de la Enfermedad , Piel/efectos de los fármacos , Triamcinolona Acetonida/administración & dosificación , Adulto JovenRESUMEN
Laser hair removal is ever increasing in popularity. Technology is fast advancing, and there are increasingly excessive commercial claims that laser hair removal in all skin types is free of side effects. The aim of this study is to review the evidence from published literature regarding the incidence of adverse effects after laser and light systems for hair removal. A review of the current published literature on the ill effects reported after laser/light-assisted depilation was conducted. Overall incidence of adverse effects after laser/light hair removal appears to be low, with very uncommon permanent sequelae. The two largest studies to date have shown that acute and transient side effects do occur. Higher incidence of pigmentary alterations is associated with the shorter wavelength lasers (up to 19%), particularly with darker skin types, compared with lower incidence using the neodymium-yttrium-aluminium-garnet laser (2-3%). Both studies did not show any long-term side effects or scarring. Laser/light hair removal, carried out by trained professionals, is a safe procedure with a very low incidence of permanent sequelae. The majority of adverse effects are transient and minor. They are more common in darker skin. Longer wavelength devices reduce the risk in darker skin.
Asunto(s)
Remoción del Cabello/efectos adversos , Hirsutismo/terapia , Rayos Láser/efectos adversos , Enfermedades de la Piel/etiología , Humanos , Incidencia , Medición de Riesgo , Factores de RiesgoRESUMEN
BACKGROUND: The pulsed-dye laser (PDL) is the treatment of choice for port-wine stains (PWS). Multiple treatments are usually necessary, with standard treatment intervals ranging between 6 and 12 weeks. However, there are no studies on the effect of treating PWS at different time intervals, and the ideal time interval between treatments has not yet been agreed. It is uncertain whether treatment is more effective if administered at shorter time intervals. OBJECTIVES: To establish whether the treatment of PWS with the variable pulse width 595-nm (V-beam) PDL at 2-week intervals achieves better results, with no difference in the complication rate, than treatment given at 6-week intervals. METHODS: We prospectively investigated 15 patients with PWS. Each patient had the whole PWS treated at initial visit. Half of the PWS was randomly allocated to be treated at 2 weeks and the other half at 6 weeks from initial visit. Both halves of the PWS thus were treated twice in total, once at the initial visit and the second treatment either at 2 weeks or 6 weeks from initial visit. At 12 weeks an observer blinded to treatment allocation clinically evaluated the results. The outcome measure was lightening of the PWS as measured with a reflectance spectrophotometer. Complications were recorded throughout the study period. RESULTS: Of the 15 patients, 13 completed the study. Three patients had two PWS each treated separately, giving a total of 16 treated PWS sites. In 11 sites (69%), the 2-week interval treatment resulted in greater reduction in reflectance than the 6-week interval treatment. Using the nonparametric Wilcoxon matched-pair signed rank test, the 2-week treatment interval site resulted in greater reduction in reflectance measurements compared with the 6-week treatment interval site (P < 0.01). This agreed closely with independent observer assessment judging that the 2-week treatment interval resulted in better lightening of the PWS than the 6-week treatment interval (P = 0.003). There were no adverse reactions from the treatments. CONCLUSIONS: Preliminary data suggest that a treatment interval of 2 weeks is well tolerated by patients and resulted in greater lightening of the PWS in the majority, compared with a standard 6-week interval. It also has the potential to reduce the total duration of a course of treatment significantly.
Asunto(s)
Terapia por Láser , Mancha Vino de Oporto/radioterapia , Adulto , Fraccionamiento de la Dosis de Radiación , Humanos , Rayos Láser/efectos adversos , Estudios Prospectivos , Método Simple Ciego , Espectrofotometría , Factores de Tiempo , Resultado del TratamientoRESUMEN
Calciphylaxis is a rare, potentially life-threatening syndrome characterized by progressive microvascular and superficial soft tissue calcification, usually seen in patients with chronic renal failure. We describe an unusual case of calciphylaxis in a patient with alcoholic liver disease and normal renal function who responded well to conservative wound care.