RESUMEN
The authors present results of evaluation of alpha-fetoprotein (AFP) in 146 persons (108 patients with head and neck carcinoma and 38 healthy persons as control group). We analyzed a concentration of AFP in preliminary study and in monitoring depending on clinical advances of tumour, mass of primary tumour and metastases to lymph nodes. Our results indicate that evaluation of AFP have not high value in diagnostic procedures and monitoring patients with head and neck carcinoma.
Asunto(s)
Carcinoma de Células Escamosas/sangre , Carcinoma de Células Escamosas/diagnóstico , Neoplasias de Cabeza y Cuello/sangre , Neoplasias de Cabeza y Cuello/diagnóstico , alfa-Fetoproteínas/metabolismo , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Carcinoma de Células Escamosas/terapia , Estudios de Evaluación como Asunto , Femenino , Neoplasias de Cabeza y Cuello/terapia , Humanos , Metástasis Linfática/diagnóstico , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Valor Predictivo de las Pruebas , Sensibilidad y Especificidad , Factores de TiempoRESUMEN
Aim of the work was estimation of squamous cell carcinoma antigen (SCC) concentrations in serum and qualification its diagnostic value in patients with malignant neoplasm of head and neck in dependence from presence of metastasis to lymphatic glands. The study comprised the group of 146 persons (108 with head and neck malignant neoplasm, 38 of persons determined group supervisory). At 35 ill one ascertained metastasis to lymph nodes. In presented work sensitivity of SCC in initial investigation was (52.8%), specificity (97.4%), positive predicting value (PV+ = 94.2%) and negative predicting value (PV- = 64.0%). We observed not characteristic statistical dependence of concentrations SCC from presence of metastasis to lymph nodes. There was characteristic correlation between concentration of SCC and presence of metastasis to regional lymphatic glands using of correlation R-Spearman.
Asunto(s)
Antígenos de Neoplasias/metabolismo , Biomarcadores de Tumor/metabolismo , Carcinoma de Células Escamosas/metabolismo , Carcinoma de Células Escamosas/secundario , Neoplasias de Cabeza y Cuello/metabolismo , Neoplasias de Cabeza y Cuello/patología , Serpinas , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Metástasis Linfática , Masculino , Persona de Mediana Edad , Sensibilidad y EspecificidadRESUMEN
Aim of the work was estimation of Tissue Polypeptide Antigen (TPA) concentrations in serum and qualification its diagnostic value in patients with malignant neoplasm of head and neck in dependence from presence of metastasis to regional lymph nodes. The study comprised the group of 146 persons (108 with head and neck malignant neoplasm, 38 of persons determined group supervisory). At 35 ill one ascertained metastasis to lymph nodes. In presented work at ill without metastasis to lymphatic glands sensitivity of test TPA carried out 28.8%, and at ill with metastasis 42.9%, attaining 66.7% at ill from N3. One showed, that concentrations TPA grow together from spreading of neoplasm in lymph nodes, and presence of metastasis correlates with concentrations of TPA.
Asunto(s)
Biomarcadores de Tumor/sangre , Carcinoma de Células Escamosas/sangre , Neoplasias de Cabeza y Cuello/sangre , Antígeno Polipéptido de Tejido/sangre , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Carcinoma de Células Escamosas/secundario , Femenino , Neoplasias de Cabeza y Cuello/patología , Humanos , Metástasis Linfática , Masculino , Persona de Mediana EdadRESUMEN
The authors present three cases of cervical lymph nodes metastases from unknown primary lesion as a first and single sing of cancer. In follow-up the primary lesions of cancer was recognized (tonsil, hypopharynx, parotid gland). Presented patients pass through combined treatment: chemotherapy, radiotherapy and surgery with good results. Patients are in follow up of ENT Department.
Asunto(s)
Carcinoma de Células Escamosas/secundario , Neoplasias de Cabeza y Cuello/patología , Ganglios Linfáticos/patología , Adulto , Anciano , Carcinoma de Células Escamosas/terapia , Neoplasias de Cabeza y Cuello/terapia , Humanos , Metástasis Linfática , Masculino , Persona de Mediana Edad , Neoplasias Primarias SecundariasRESUMEN
The authors present all-Polish Internet Allergy Service www.allergen.info.pl working since February 1998. The system of mailing current allergenic pollen data to individual patients is presented. The results of Internet questionnaire filled by 4500 users of GlaxoWellcome Pollen Count Internet Service in 1998 are discussed. The authors also present possibility of cooperation for clinicians with the usage of IRC and picture and voice transmission.
Asunto(s)
Alergia e Inmunología , Hipersensibilidad , Internet , Humanos , PoloniaRESUMEN
The authors present the method of combined treatment of rhinophyma (surgery and laser CO2). The advantages of this method are good cosmetic result, small intraoperative bleeding and short time of healing the wound.
Asunto(s)
Dióxido de Carbono/uso terapéutico , Terapia por Láser , Rinofima/cirugía , Anciano , Humanos , Masculino , Monitoreo Intraoperatorio , Cicatrización de HeridasRESUMEN
The authors described the application of facial bone scintigraphy in 6 patients with acute and 47 patients with chronic sinusitis, 4 patients with cyst of maxillary sinus, 4 patients with sinus maxillary neoplasm and 4 patients with pyocele of frontal sinus. Facial bone scintigraphy was performed by gamma-camera Siemens Gammasonics ZLC-750 after intravenous administration of 15 mCi of 99mTcMDP in anteroposterior projection. The index of accumulation of the tracer (JAT) in maxillary sinus region was counted separately in men and in women in the reference group. In patients with purulent sinusitis marked JAT was predominated. Correlation between JAT and symptoms and rhinological signs has been shown in patients with chronic purulent sinusitis. In patients with sinus maxillary neoplasm high JAT was predominated.
Asunto(s)
Huesos Faciales/diagnóstico por imagen , Enfermedades Maxilares/diagnóstico por imagen , Neoplasias Maxilares/diagnóstico por imagen , Adulto , Anciano , Enfermedad Crónica , Femenino , Humanos , Masculino , Enfermedades Maxilares/metabolismo , Neoplasias Maxilares/metabolismo , Persona de Mediana Edad , Cintigrafía , Radiofármacos/metabolismoRESUMEN
The authors present results of evaluation of squamous cell carcinoma antigen (SCC) in 73 persons (35 patients with head carcinoma and 38 healthy persons as control group). We analysed a concentration of SCC in preliminary study and in monitoring, depending on clinical advances of tumour, mass of primary tumour and metastases to lymph nodes. We observed high sensitivity (SE) (63%), high specificity (SP) (97.4%) and predictive values: positive PV(+)--95.6%, negative PV(-)--74% of SCC in preliminary study. These values changed to SE--83.3%, SP--92.3%, PV(+) 90.9%, PV(-)--85.7% in monitoring. Our results indicate that evaluation of SCC have high value in monitoring patients with head carcinoma.
Asunto(s)
Antígenos de Neoplasias/análisis , Biomarcadores de Tumor/análisis , Carcinoma de Células Escamosas/diagnóstico , Neoplasias de Cabeza y Cuello/diagnóstico , Serpinas , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Carcinoma de Células Escamosas/secundario , Femenino , Humanos , Metástasis Linfática , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Sensibilidad y EspecificidadRESUMEN
The authors present the results of examinations of test on the sensitivity of biochemical tumor marker (Ca 19-9) in a group of 35 patients with head malignant tumors. The sensitivity (SE) of Ca 19-9 was 22.9% in preliminary study. The values of Ca 19-9 changed from 22.9% to 25.9% in monitoring of tumors. Positive predictive value (PV+) and specify (SP) were 100% in preliminary study and in monitoring. Negative predictive value (PV-) was 50.9% in preliminary study and 51.6% in monitoring. In 25 patients we observed changes in examined parameters: SE--35%, SP--100%, PV(+)--100%, PV(-)--42.1% in monitoring. Our study indicates that serum levels of Ca 19-9 were higher in patients with head tumors than in control group. The surgical treatment of tumors didn't change the values of Ca 19-9.
Asunto(s)
Biomarcadores de Tumor/inmunología , Antígeno CA-19-9/inmunología , Neoplasias de Cabeza y Cuello/inmunología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Biomarcadores de Tumor/sangre , Antígeno CA-19-9/sangre , Femenino , Neoplasias de Cabeza y Cuello/cirugía , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las PruebasRESUMEN
The authors present the results of examinations of immunoglobulins A, G, M serum concentrations and of a sensitivity of test of biochemical tumor marker (Ca 19-9) in a group of 35 patients with head malignant tumors. There was a statistically significant increase of immunoglobulins IgA, IgG and decrease of immunoglobulin IgM. We observed statistical correlation between serum concentrations of IgA, IgG and serum concentrations of IgA, IgM. The sensitivity of Ca 19-9 was 23% in the preliminary study. The values of Ca 19-9 changed in monitoring of tumors to 26%. There was a statistically significant correlation between sensitivity of Ca 19-9 and serum concentration of IgM. We did not observe any statistical correlation between Ca 19-9 and the age of patients.
Asunto(s)
Antígeno CA-19-9/inmunología , Neoplasias Gastrointestinales/inmunología , Neoplasias de Cabeza y Cuello/inmunología , Inmunoglobulinas/sangre , Inmunoglobulinas/inmunología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Anticuerpos Antineoplásicos/inmunología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Estudios RetrospectivosRESUMEN
The authors described a case of parapharyngeal space pleomorphic adenoma in a 22-year-old patient. The excision of the tumor through the mouth, without cutting up the jaw bone, turned out safe and radical.
Asunto(s)
Adenoma Pleomórfico/diagnóstico , Neoplasias de las Glándulas Salivales/diagnóstico , Adenoma Pleomórfico/cirugía , Adulto , Angiografía , Humanos , Masculino , Neoplasias de las Glándulas Salivales/cirugía , Tomografía Computarizada por Rayos XRESUMEN
The authors described diagnostics difficulties, clinical features and treatment of this disease. The treatment is insufficient, but only interventional, although the clinically dominating symptoms may be due to a chronic disease inside of the sinuses and they are known to be caused by specific disorders in immunology. Immunosuppression, using prednisone, and reestablishing sinus ventilation and drainage via natural ostia is the basis of treatment, but it does not lead to recovery. Two rare cases of paranasal sinuses sarcoidosis are described.
Asunto(s)
Enfermedades de los Senos Paranasales/cirugía , Sarcoidosis/cirugía , Adulto , Femenino , Humanos , Persona de Mediana Edad , Enfermedades de los Senos Paranasales/diagnóstico , Sarcoidosis/diagnósticoRESUMEN
The inflammatory pathologies of the ENT tract are often characterized by presence of catarral, mucous-purulent and crusty secretions. In such cases, an efficient therapy has to change the dense secretions as first and then remove them. "Rinoflow" is a compressor-micronizer chamber system specially designed for treatment of affections of upper respiratory tract. We used Rinflow in treatment of 62 patients (23 female and 39 male, mean age 42.7 years) with chronic paranasal sinusitis. The results of treatment were estimated by patients, physicians and X-ray examinations. We observed in 37 patients (59.7%) good results after treatment. The use of "rinoflow" was practically effected when the secretions were blocking the natural ostium of paranasal sinuses.
Asunto(s)
Nebulizadores y Vaporizadores , Sinusitis/terapia , Adolescente , Adulto , Enfermedad Crónica , Diseño de Equipo , Femenino , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Sinusitis/diagnóstico por imagen , Resultado del TratamientoRESUMEN
The laryngeal papilloma is very doubtful disease in children. The unknown etiology cause that there wasn't complete radical method in the treatment of laryngeal papilloma. Authors presented a case of 11 years old girl with recurrent laryngeal papilloma, who was treated twice with laser microsurgery without successful results. The 6 months application of interferon alfa after third laser microsurgery resulted in more than one year of remission of the disease.
Asunto(s)
Interferones/uso terapéutico , Neoplasias Laríngeas/terapia , Terapia por Láser/métodos , Papiloma/terapia , Niño , Terapia Combinada , Femenino , HumanosRESUMEN
The authors present the method of combined treatment of rhinophyma (surgery and laser CO2). The advantages of this method are good cosmetic result, small intraoperating bleeding and short time of healing the wound.
Asunto(s)
Terapia por Láser/métodos , Rinofima/cirugía , Anciano , Dióxido de Carbono/uso terapéutico , Humanos , MasculinoRESUMEN
In the Clinic of Otolaryngology Central Clinical Hospital Military School of Medicine in Warsaw in years 1992-1996 there were performed 187 endoscopic operations of nose and paranasal sinuses. Authors analised own material paying particular attention to indications, benefits and failures of these operations. Authors postulate that indications for clinical diagnostic and therapeutic procedures of this technique should be considerably extended in diseases of nose and paranasal sinuses. The application of endoscopic sinus surgery in our Clinic decreased the number of more extended operations of paranasal sinuses.
Asunto(s)
Endoscopía/métodos , Enfermedades de los Senos Paranasales/cirugía , Adolescente , Adulto , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
A physician wanting to help his hay fever patient efficiently needs to know the causative agent in detail. High qualitative and quantitative variability in certain years creates the necessity of constant pollen count monitoring. Information on current trends is helpful to doctors in their diagnostic and prophylactic procedures as well as in efficient treatment planning.
Asunto(s)
Alérgenos/efectos adversos , Polen/efectos adversos , Rinitis Alérgica Estacional/etiología , Humanos , Rinitis Alérgica Estacional/diagnóstico , Rinitis Alérgica Estacional/prevención & controlRESUMEN
Authors present perennial immunotherapy procedure that they developed with sublingal Perosall T 13 and Novo-Helisen Depot. The results of two-year observation of 70 patients undergoing above mentioned therapy.
Asunto(s)
Rinitis Alérgica Perenne/terapia , Adolescente , Adulto , Femenino , Humanos , Inmunoterapia/métodos , MasculinoRESUMEN
Basis clinical proceeders in hearing loss diagnosis and the instruments used in the Department of Otolaryngology of the Military Medical Academy in Warsaw were presented.
Asunto(s)
Trastornos de la Audición/diagnóstico , Personal Militar , Academias e Institutos , Humanos , Otolaringología , PoloniaRESUMEN
The authors present the results of treatment of chronic maxillary sinusitis with punctures and with permanent drainage (sino-ject). The use of permanent drainage shortened the time of treatment and increased percentage of very good results of treatment. Presented method of permanent drainage of maxillary sinus avoid many punctures of sinus. The drainage of sinus allow for each day rinsing of sinus with physiological saline and with drugs (mucolitic, antibiotic) and also for bacteriological examination of sinus secretion. As in classical puncture of maxillary sinus the permanent drainage play a diagnostic and therapeutic roles. The permanent drainage of maxillary sinus allow for inflow of oxygen into sinus and protect from anaerobic infection. The fact that puncture needle is pushed to a depth of only 1 cm greatly reduces the risk of injuring neighbouring structures. This method enables puncture of maxillary sinus with minimum trauma and hardly any pain.