RESUMEN

Muscle metabolites were obtained by in vivo proton magnetic resonance spectroscopy of 3 patients with Duchenne muscular dystrophy (DMD), 6 patients with spinal muscular atrophy (SMA), and 10 normal volunteers. Patients with DMD and SMA had lower trimethyl amide (TMA)/water and TMA/total creatine (tCr) ratios but normal tCr/water ratios.

Asunto(s)

Músculo Esquelético/metabolismo , Atrofia Muscular Espinal/metabolismo , Distrofia Muscular de Duchenne/metabolismo , Tejido Adiposo/metabolismo , Adolescente , Niño , Preescolar , Creatina/metabolismo , Femenino , Humanos , Espectroscopía de Resonancia Magnética , Masculino , Metilaminas/metabolismo