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[Interaction of hemoglobin with phospholipid vesicular membranes of different composition]. / Izuchenie vzaimodeistviia gemoglobina s fosfolipidnymi vezikuliarnymi membranami razlichnogo sostava.

Bondarenko, S V; Ushakova, I P; Levit, L F; Serebrennikova, G A; Evstigneeva, R P.

Bioorg Khim ; 11(10): 1385-90, 1985 Oct.

Artículo en Ruso | MEDLINE | ID: mdl-4074398

RESUMEN

Incorporation of hemoglobin into vesicles and its oxidation were studied as a function of composition of the vesicular membrane containing erythrocyte membrane lipids as main components. The addition of negatively charged lipids such as phosphatidylserine and phosphatidic acid, was shown to considerably increase the extent of hemoglobin binding, while sphingomyelin did not produce such an effect. Cholesterol and dipalmitoylphosphatidylcholine stabilized oxyHb.

Asunto(s)

Membrana Eritrocítica/metabolismo , Hemoglobinas/metabolismo , Lípidos de la Membrana/metabolismo , Fosfolípidos/metabolismo , Humanos , Técnicas In Vitro , Membrana Dobles de Lípidos/metabolismo , Oxihemoglobinas/metabolismo , Espectrofotometría

RESUMEN

Asunto(s)

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