RESUMEN

Ectopic adrenocorticotropic hormone secretion (EAS) from the pancreatic neuroendocrine tumour (PNET) is rare, aggressive, and challenging to treat. We hereby present a rare case of EAS from PNET presenting with Cushing syndrome diagnosed with endoscopic ultrasound-guided fine-needle aspiration cytology. This case highlights the advanced presentation of EAS from PNET with poor clinical correlation of hypercortisolism and the grade of PNET.

A secreção ectópica de hormona adrenocorticotrópica (SEA) por tumores neuroendócrinos pancreáticos (TNE-P) é rara, agressiva e difícil de tratar. Apresentamos um caso raro de SEA por TNE-P apresentando-se com síndroma de Cushing, diagnosticado através de ecoendoscopia com punção aspirativa com agulha fina. Este caso enfatiza a apresentação avançada dos TNE-P com SEA e a correlação baixa com o grau de hipercortisolismo e o grau do TNE-P.

RESUMEN

Barrett's esophagus, which results from chronic gastroesophageal reflux disease, is a known precursor to dysplasia and ultimately esophageal adenocarcinoma. Mixed neuroendocrine - nonneuroendocrine neoplasm (MiNEN) is a rare and heterogenous group of neoplasm with aggressive clinical behavior in general. There have been rare reports of MiNEN arising in Barrett's esophagus, and its pathogenesis remains unclear. Surgical resection with lymph node dissection remains the most effective treatment of MiNEN of the esophagus to date, although the evidence on its optimal treatment is scant. How to cite this article: Lee SL, Ng CY, Gew LT, et al. Mixed Neuroendocrine - Nonneuroendocrine Neoplasm Arising in Barrett's Esophagus. Euroasian J Hepato-Gastroenterol 2022;12(1):57-59.

RESUMEN

Cervical adenocarcinoma accounts for 25% of invasive cervical cancer which frequently metastasize distantly to the lungs, liver, bone, and brain. Metastases to the common bile duct from cervical cancer are exceedingly rare with few reported cases in the literature. Diagnosis of bile duct metastases from cervical cancer can be established with endoscopic ultrasound-guided fine-needle aspiration cytology, biliary cytobrushing, or direct cholangioscopy with biopsy, and this would guide further therapies such as endoscopic biliary drainage and systemic chemotherapy. We hereby present a rare case of obstructive jaundice from metastatic biliary stricture with "beaded" appearance in a patient with cervical adenocarcinoma. How to cite this article: Lee SL, Sidhu J, Ng CY. Metastatic Biliary Stricture with "Beaded" Appearance from Cervical Adenocarcinoma. Euroasian J Hepato-Gastroenterol 2021;11(2):97-99.