RESUMEN

The authors describe a case of relapse of Neisseria meningitidis serogroup B meningitis in a 21-y-old male, 48 h after a 5-day treatment with cefotaxime 215 mg/kg per day. Brain magnetic resonance imaging (MRI) excluded the hypothesis of cerebral abscess or central venous septic thrombosis, and transthoracic echocardiography excluded bacterial endocarditis. Complement, properdin, and protein electrophoresis were normal. The plausible explanations for this relapse and the implications for other similar cases are discussed.

Asunto(s)

Antibacterianos/uso terapéutico , Cefotaxima/uso terapéutico , Meningitis Meningocócica/tratamiento farmacológico , Neisseria meningitidis Serogrupo B/aislamiento & purificación , Antiinflamatorios/uso terapéutico , ADN Bacteriano/líquido cefalorraquídeo , Dexametasona/uso terapéutico , Humanos , Masculino , Meningitis Meningocócica/microbiología , Meningitis Meningocócica/fisiopatología , Neisseria meningitidis Serogrupo B/genética , Recurrencia , Adulto Joven