RESUMEN
The ultimate goal of research was to make a comparative evaluation of efficiency of periodontitis treatment with alpha-lipoic acid in the short-term and long-term period in people which are under the influence of heavy metal salts of low intensity. 50 patients residing on the territory under the influence of heavy metal salts of low intensity, were under observation and they were given medical treatment to evaluate the efficiency of periodontitis treatment with the help of alpha-lipoic acid in short-term and long-term period. The patients were undergone clinical evaluation of periodontal status according to general indexes and data of laboratory examinations prior to treatment, in 14 days and in 12 months. After intaking of 600 mg of alpha-lipoic acid per day during 14 days the condition of periodontitis tissues in the reference group and in the basic group has no statistically significant differences. The basic group took alpha-lipoic acid during 2 months, that favored improving of clinical and laboratory indexes. In comparison with the reference group in the basic group PMA index decreased in 2.3 times, IIS in 1.4 times, BPI in 1.8 times, complex parodontal index improved in 1.3 times, leucocytes emigration decreased in 1.2 times and microbial contamination of epithelium in 1.22 times. Efficiency of anti-inflammatory therapy was 1.4 times higher. Depth of gingival pockets and level of oral hygiene had no statistical significant differences.
Asunto(s)
Bolsa Gingival/inducido químicamente , Bolsa Gingival/patología , Periodontitis/patología , Ácido Tióctico/administración & dosificación , Antibacterianos/administración & dosificación , Bolsa Gingival/tratamiento farmacológico , Humanos , Metales Pesados/toxicidad , Higiene Bucal , Periodontitis/inducido químicamente , Periodontitis/tratamiento farmacológico , Sales (Química)/toxicidadAsunto(s)
Odontalgia/diagnóstico , Enfermedad Aguda , Diagnóstico Diferencial , Humanos , Odontalgia/etiologíaRESUMEN
Common methods for microbiologic examination of the gingival pocket contents in periodontitis are rarely used in practical periodontology. The author proposes to quantify epithelial cells contaminated by bacterial flora. Results of cytologic studies of smear impressions from 30 patients with periodontal diseases and from 13 normal subjects are presented, evidencing a significant elevation of bacterial contamination of the epithelium in the patients vs. that in normal subjects (66.51 +/- 3.5 vs. 44.66 +/- 4.75 percent).
Asunto(s)
Bacterias/aislamiento & purificación , Bolsa Gingival/microbiología , Periodontitis/microbiología , Células Epiteliales , Epitelio/microbiología , HumanosRESUMEN
The routine method for estimation of the count of leukocytes that migrated to the oral cavity, making use of a special chamber, is difficult. The author suggests leukocyte scintillation in 1 microliter of oral washing in Goryayev's chamber. The data of 83 analyses of oral washings carried out in patients with different patterns of inflammatory processes in periodontal tissues are presented.