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Chem Commun (Camb) ; 55(57): 8246-8249, 2019 Jul 11.
Artículo en Inglés | MEDLINE | ID: mdl-31243405

RESUMEN

A dual-emissive fluorescent probe enabling dynamic changes in nuclear local microviscosity monitoring was developed. The new sensing scenario involves probe subcellular localization redistribution, allowing a quantitative analysis of the local microviscosity related to nuclear damage in the presence of agents perturbing the nuclear morphology. With the aid of an organotin(iv) in situ formed complex we propose a different scenario of bioanalytical applications through confocal microscopy.

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