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Clin Neurophysiol ; 117(11): 2540-8, 2006 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-17000133

RESUMEN

OBJECTIVE: Inattention is undoubtedly one of the main characteristics of Attention-deficit hyperactivity disorder (ADHD). Nevertheless, a growing corpus of evidence shows that not all attentional processes are affected in this condition. This study aimed to explore the distribution of attentional resources in children with ADHD via a spatially shifted double-oddball visual task. METHODS: We recorded event-related potentials (ERPs) for all visual stimuli. Subjects were instructed to allocate attention in a specific area of visual space while ignoring all stimuli presented outside. Ten male children (age: 9-14; mean = 11.6 +/- 2.1) who met DSM-IV criteria for the ADHD combined subtype participated in the study, along with ten age- and sex-matched healthy controls (9-14; mean = 11.2 +/- 2.3). RESULTS: ADHD subjects showed late differential cortical responses to initially suppressed irrelevant stimuli. The amplitude of early N1-P1 components were mainly modulated by stimulus location and showed no significant differences between groups, but a late P300-like positivity was clearly evoked in the ADHD group by peripheral stimuli. CONCLUSIONS: These results suggest that ADHD may not compromise the early attentional spatial filter but rather entails a different distribution of attentional resources at later stages of cortical processing. Perhaps these differences may be attributable to individual differences in attentional mechanisms. SIGNIFICANCE: ADHD may not affect initial focusing of visual attention but rather the allocation of processing resources in later stages.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad/fisiopatología , Atención/fisiología , Corteza Cerebral/fisiopatología , Percepción Espacial/fisiología , Percepción Visual/fisiología , Adolescente , Trastorno por Déficit de Atención con Hiperactividad/psicología , Mapeo Encefálico , Niño , Señales (Psicología) , Potenciales Relacionados con Evento P300/fisiología , Potenciales Evocados/fisiología , Fijación Ocular , Humanos , Pruebas de Inteligencia , Masculino , Estimulación Luminosa , Escalas de Valoración Psiquiátrica
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