RESUMEN
Methods of estimation of the airway resistance by flow-pressure curve obtained in whole-body plethysmography are investigated. The analysis of the physical processes controlling the flow-limitation during expiration shows that these methods are useful only for healthy subjects for the estimation of the airway resistance. The way for estimation of the airway resistance by flow-pressure curve is proposed.
Asunto(s)
Resistencia de las Vías Respiratorias , Pletismografía Total/métodos , Bronquitis/fisiopatología , Enfermedad Crónica , Flujo Espiratorio Forzado , Humanos , Enfisema Pulmonar/fisiopatología , Valores de ReferenciaRESUMEN
The experiments on the dogs revealed that the damage of lobar bronchus conduction resulted in the decrease of O2 tension in pulmonary venous blood of this lobe. The decrease in the ventilation and blood flow was found in the zone of obstruction by using tracers 133Xe and 99mTc. The pressure rise in the pulmonary artery caused by the spread of bronchial obstruction is one of the factors promoting the redistribution of perfusion into the reserve zones of lungs. The decrease of pressure by the ganglio-blocking preparation results in the increase of arterial hypoxemia.
Asunto(s)
Presión Sanguínea , Bronquios/fisiopatología , Enfermedades Pulmonares Obstructivas/fisiopatología , Arteria Pulmonar/fisiología , Intercambio Gaseoso Pulmonar , Animales , Perros , Masculino , Oxígeno/sangre , Circulación Pulmonar , Tecnecio , Relación Ventilacion-Perfusión , Radioisótopos de XenónRESUMEN
Upon the comparison for Leningrad citizens, CNPD sanatorium treatment in climatic conditions of Leningrad Region was inferior in noway to that in southern climates of Yalta and Kislovodsk resorts as regards to relevant therapeutic response.
Asunto(s)
Enfermedades Bronquiales/terapia , Clima , Colonias de Salud , Enfermedades Pulmonares/terapia , Aclimatación , Adulto , Estudios de Evaluación como Asunto , Humanos , Persona de Mediana Edad , U.R.S.S.Asunto(s)
Flujo Espiratorio Forzado , Respiración , Adulto , Fenómenos Biomecánicos , Femenino , Humanos , MasculinoAsunto(s)
Resistencia de las Vías Respiratorias , Pulmón/fisiología , Respiración , Adulto , Fenómenos Biomecánicos , Femenino , Humanos , MasculinoRESUMEN
To improve the diagnosis of primary lung emphysema etiologically linked with alpha-trypsin deficiency, the authors provide the results of a detailed clinico-functional study of 6 patients with an appreciable deficiency of this enzyme. According to the clinical and functional signs, all the patients were diagnosed to have a typical, pronounced lung emphysema. Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.