RESUMEN
The authors evaluated vegetative homeostasis and higher nervous activities in individuals working with various wood antiseptics. The work with the antiseptics free of chlorphenols appears to increase parasympathetic activity; longer length of work with chlorphenol antiseptics activates sympathetic system. Contact with chemicals speeds up nervous processes and changes relationships between brain structures associated with decision making and motor activity regulation.
Asunto(s)
Antiinfecciosos Locales/efectos adversos , Enfermedades del Sistema Nervioso Autónomo , Frecuencia Cardíaca/fisiología , Enfermedades Profesionales , Madera , Adulto , Enfermedades del Sistema Nervioso Autónomo/inducido químicamente , Enfermedades del Sistema Nervioso Autónomo/fisiopatología , Enfermedades del Sistema Nervioso Autónomo/psicología , Humanos , Persona de Mediana Edad , Enfermedades Profesionales/inducido químicamente , Enfermedades Profesionales/fisiopatología , Enfermedades Profesionales/psicologíaRESUMEN
The authors report on creation of domestic chlorophenol-free preservatives for wood (EOK, K-12, Katan) in Arkhangelsk Research Institute. Application of those chemicals is cheaper than that of foreign analogs. Toxicity of the preservatives was evaluated according to morphologic and functional changes in various organs and systems of experimental animals which faced long exposure to the preservatives. The experiments proved K-12 to be the most pathogenic among others. EOK preservative fails to induce severe pathologic changes in experimental animals, demonstrated no cumulation and allergy. Katan takes intermediate place between those two.
Asunto(s)
Desinfectantes/toxicidad , Madera , Animales , Clorofenoles/toxicidad , Femenino , Ratones , Ratones Endogámicos CBARESUMEN
One of the aspects of antagonistic relations could be the competence of microorganisms for specific sites of attachement to the epithelium common for shigellae and some E. coli serological types; this was demonstrated on a model of shigella-induced keratoconjunctivitis and in experiments with the HEp-2 cells infected with H3-glucose-labeled Sh. flexneri 5a, with combined administration of the latter with E. coli 08 and 028. The data obtained emphasized the importance for the development of the infectious process of the primary stage of shigella attachment to the epithelium. It was also revealed that the presence of common pili in the strains or production of colicine by bacteria intensified the antagonistic activity of E. coli, irrespective of their serological type.