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Meckel's diverticulum (MD) occurs in 2% of the population and is often asymptomatic. It is an embryological remnant of the oomphalomesenteric duct and can be associated with another embryonic structure-the urachus. A 23-year-old male presented with generalized abdominal pain and fever on a background of chronic abdominal pain and recurrent urinary infections. A CT scan of the abdomen and pelvis revealed an inflamed MD. Next day, the patient deteriorated and was taken to theatre. The MD was found to be both perforated and tethered to the umbilicus, which itself was directly related to an abnormal extra-peritoneal structure-shown to be a urachal remnant. Such cases pose diagnostic and therapeutic challenges. Young males with chronic abdominal pain and recurrent urinary infections should be thoroughly investigated for such pathology. Laparoscopic approach to such cases should be undertaken with caution due to possible umbilical tethering.
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Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) have been shown to improve metabolic comorbidities as well as quality of life (QoL) in the obese population. The vast majority of previous studies have investigated the metabolic effects of bariatric surgery and there is a dearth of studies examining long-term QoL outcomes post bariatric surgery. The outcomes of 43 patients who underwent bariatric surgery were prospectively assessed, using BAROS questionnaires to quantify QoL and metabolic status pre-operatively, at 1 year and at 8 years. Total weight loss and comorbidity resolution were similar between RYGB and SG. The RYGB cohort experienced greater QoL improvement from baseline and had higher BAROS scores at 8 years. RYGB may provide more substantial and durable long-term benefits as compared to SG.
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Derivación Gástrica , Laparoscopía , Obesidad Mórbida , Gastrectomía , Humanos , Obesidad Mórbida/cirugía , Calidad de Vida , Estudios Retrospectivos , Resultado del TratamientoRESUMEN
OBJECTIVE: There is evidence that executive function, and specifically inhibitory control, is related to obesity and eating behavior. The goal of this study was to determine whether personality traits and inhibitory control predict weight loss after bariatric procedures. Although the impressive weight reduction after bariatric surgery has been shown in short- and medium-term studies, the effect of personality traits on this reduction is uncertain. Specifically, the effect of impulsivity is still largely unknown. SETTING: Patients attending either a multidisciplinary information session or outpatient clinic at the Imperial Weight Management Centre were recruited with informed consent into the trial over a 4-month period from January to April 2013. Participants were invited to attend behavioral testing on an outpatient basis in a silent room invigilated by a single researcher. METHODS: Forty-five bariatric patients participated in the study (25 patients had a gastric bypass, with a mean BMI of 41.8 and age of 39.0 years; 20 had a sleeve gastrectomy, with a mean BMI of 47.2 and age of 49.0 years). All patients completed personality measures of impulsivity-Barratt's Impulsivity Scale, as well as behavioral measures of impulsivity-the stop-signal reaction-time (SSRT) task measuring inhibitory control and the temporal discounting task measuring reward processing. Those measures were examined in relation to weight loss 6 months after surgery. RESULTS: The surgical procedure and changes in the behavioral measure of inhibitory control (SSRT) were found to be significant predictors of reduction in body mass index (BMI) in patients undergoing bariatric surgery. The sleeve gastrectomy group found a reduction in BMI of 14.1%, which was significantly less than the 25% reduction in BMI in the gastric bypass group. The direction (parameter estimate) of the significant effect was positive for SSRT change, which indicates that pre- and postreduction in impulsivity predicts reduction in BMI. CONCLUSION: Impulsivity measures predict weight reduction in patients undergoing bariatric surgery. This result has implications for predicting outcomes from surgical treatments of obesity.
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Cirugía Bariátrica/psicología , Conducta Impulsiva , Obesidad/psicología , Pérdida de Peso/fisiología , Adulto , Índice de Masa Corporal , Femenino , Gastrectomía/psicología , Derivación Gástrica/psicología , Humanos , Masculino , Persona de Mediana Edad , Obesidad/cirugíaRESUMEN
BACKGROUND: North American medical schools have used problem-based learning (PBL) structured medical education for more than 60 years. However, it has only recently been introduced in other medical schools outside of North America. Since its inception, there has been the debate on whether the PBL learning process predisposes students to select certain career paths. OBJECTIVES: To review available evidence to determine the predisposition of specific career paths when undertaking a PBL-based medical curriculum. The career path trajectory was determined as measured by official Matching Programs, self-reported questionnaires and surveys, and formally defined career development milestones. METHODS: A systematic literature review was performed. PubMed, Medline, Cochrane and ERIC databases were analysed in addition to reference lists for appropriate inclusion. RESULTS: Eleven studies fitting the inclusion criteria were identified. The majority of studies showed that PBL did not predispose a student to a career in a specific speciality (n = 7 out of 11 studies, 64%). However, three studies reported a significantly increased number of PBL graduates working in primary care compared to those from a non-PBL curriculum. CONCLUSIONS: PBL has been shown not to predispose medical students to a career in General Practice or any other speciality. Furthermore, a greater number of similar studies are required before a definitive conclusion can be made in the future.
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Selección de Profesión , Curriculum , Educación Médica , Aprendizaje Basado en Problemas , Estudiantes de Medicina , Humanos , Internado y Residencia , Atención Primaria de Salud , Proyectos de Investigación , Facultades de Medicina , Encuestas y CuestionariosRESUMEN
OBJECTIVES: Obesity is a rising problem in adolescents related to unhealthy behaviours. Commitment devises are one type of behavioural intervention that may help people change their behaviours. The current pilot trial tests whether commitment devices delivered via text message help adolescents maintain their recent weight loss. METHODS: During a 12-week pilot trial, adolescents who attended a weight loss camp were randomly assigned to either received text messages that contained only information, i.e. advice, about weight loss management (n = 13) or asked for them to commit to following the same advise (n = 14). RESULTS: The BMI of the adolescents in the commitment group did not change. In contrast, the BMI of adolescents in the information group increased. A linear regression revealed that group was a significant predictor of BMI change. A logistic regression revealed that adolescents in the information group were nearly eight times more likely to regain weight than those in the commitment group. CONCLUSIONS: This is the first study with adolescents to show weight maintenance using a commitment device. The results suggest that commitment devices can help adolescents maintain their recent weight loss.
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Terapia Conductista/métodos , Obesidad/psicología , Obesidad/terapia , Pérdida de Peso , Adolescente , Femenino , Humanos , Modelos Logísticos , Masculino , Proyectos Piloto , Envío de Mensajes de Texto , Resultado del TratamientoRESUMEN
Obesity is common amongst patients with renal transplants (RT). It is associated not only with generic obesity-related complications including diabetes, but also with higher rates of graft rejection and loss. A Best Evidence Topic in surgery was written according to a structured protocol: this is a systematic review of the literature, suitable when the quality of available evidence is low. The question addressed was: is weight-loss surgery (WLS) safe and effective in patients that have had a previous renal transplant? Three prospective case series and one multicentre retrospective study were identified, together reporting on a total of 112 patients who underwent WLS after RT. Eighty-seven patients underwent open WLS and 25 patients underwent laparoscopic operations of which 11 had sleeve gastrectomy and 14 RYGB. Percentage excess weight loss was highly variable between the studies, ranging from an average of 30.8%-75% at 12 months. One graft rejection occurred within 30 days of surgery. All studies were limited by lack of suitable comparison group, short follow-up and heterogeneity in type of bariatric procedure and approach. To date, there is limited evidence to suggest that bariatric surgery is safe and has good short-term outcomes for selected obese patients post-renal transplant.
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Cirugía Bariátrica , Trasplante de Riñón , Adulto , Cirugía Bariátrica/efectos adversos , Cirugía Bariátrica/métodos , Femenino , Gastrectomía/métodos , Rechazo de Injerto , Humanos , Laparoscopía/métodos , Masculino , Persona de Mediana Edad , Obesidad/complicaciones , Obesidad Mórbida/cirugía , Pérdida de PesoRESUMEN
Obesity is associated with multiple comorbidities and psychosocial burdens, but often sexual dysfunction (SD) is overlooked. Bariatric surgery is the most effective treatment for morbid obesity, and its role in reversing SD is reviewed. A literature search of MEDLINE, PubMed Central, and Cochrane databases was conducted. Fifty-six articles were identified and 32 selected for inclusion. SD was measured via hormonal studies, questionnaires, and a combination of both (n = 14 males SD studies, n = 13 female SD studies, 5 = both sexes). There is an exponential rise in patients reporting post-surgical improvements in SD in both genders. The emerging use of quality of life indices to measure sexual function as part of a more global enjoyment of life may be a helpful adjunct to existing hormonal and sex-specific measures.
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Cirugía Bariátrica , Obesidad/cirugía , Calidad de Vida , Disfunciones Sexuales Fisiológicas/cirugía , Disfunciones Sexuales Psicológicas/cirugía , Femenino , Humanos , Masculino , Obesidad/complicaciones , Obesidad/fisiopatología , Obesidad/psicología , Disfunciones Sexuales Fisiológicas/complicaciones , Disfunciones Sexuales Psicológicas/complicaciones , Pérdida de PesoRESUMEN
Benign tumours of the bone are not cancerous and would not metastasise to other regions of the body. However, they can occur in any part of the skeleton, and can still be dangerous as they may grow and compress healthy bone tissue. There are several types of benign tumours that can be classified by the type of matrix that the tumour cells produce; such as bone, cartilage, fibrous tissue, fat or blood vessel. Overall, 8 different types can be distinguished: osteochondroma, osteoma, osteoid osteoma, osteoblastoma, giant cell tumour, aneurysmal bone cyst, fibrous dysplasia and enchondroma. The incidence of benign bone tumours varies depending on the type. However, they most commonly arise in people less than 30 years old, often triggered by the hormones that stimulate normal growth. The most common type is osteochondroma. This review discusses the different types of common benign tumours of the bone based on information accumulated from published literature.
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BACKGROUND: Surgical training is changing and evolving as time, pressure, and legislative demands continue to mount on trainee surgeons. A paradigm change in the focus of training has resulted in experts examining the cognitive steps needed to perform complex and often highly pressurized surgical procedures. OBJECTIVE: To provide an overview of the collective evidence on cognitive task analysis (CTA) as a surgical training method, and determine if CTA improves a surgeon's performance as measured by technical and nontechnical skills assessment, including precision, accuracy, and operative errors. METHODS: A systematic literature review was performed. PubMed, Cochrane, and reference lists were analyzed for appropriate inclusion. RESULTS: A total of 595 surgical participants were identified through the literature review and a total of 13 articles were included. Of these articles, 6 studies focused on general surgery, 2 focused on practical procedures relevant to surgery (central venous catheterization placement), 2 studies focused on head and neck surgical procedures (cricothyroidotomy and percutaneous tracheostomy placement), 2 studies highlighted vascular procedures (endovascular aortic aneurysm repair and carotid artery stenting), and 1 detailed endovascular repair (abdominal aorta and thoracic aorta). Overall, 92.3% of studies showed that CTA improves surgical outcome parameters, including time, precision, accuracy, and error reduction in both simulated and real-world environments. CONCLUSION: CTA has been shown to be a more effective training tool when compared with traditional methods of surgical training. There is a need for the introduction of CTA into surgical curriculums as this can improve surgical skill and ultimately create better patient outcomes.
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Educación Médica/métodos , Cirugía General/educación , Modelos Teóricos , Cirujanos/educación , Cirujanos/estadística & datos numéricos , Competencia Clínica , Simulación por Computador , HumanosRESUMEN
Students applying to medical school may benefit from a better understanding of the clinical environment and the duties of a doctor. Despite attachments at hospital they may feel detached from the decision making process which is a pivotal part of being a clinician. A simulated hospital environment was tried on 30 pre-med students from an urban environment to test the feasibility of using structured clinical scenarios to augment their experience of a clinical setting.
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Instrucción por Computador/métodos , Educación Premédica/métodos , Enseñanza Mediante Simulación de Alta Fidelidad/métodos , Hospitales , Imagenología Tridimensional/métodos , Simulación de Paciente , Estudios de Factibilidad , Reino Unido , Interfaz Usuario-ComputadorRESUMEN
INTRODUCTION: There are a vast array of smartphone applications that could benefit both surgeons and their patients. To review and identify all relevant surgical smartphone applications available for the Apple iPhone iOS and Google Android platform based on their user group and subspecialty for which they were designed. METHOD: Both the literature using PubMed and Google Scholar were searched using the following terms: application$, smartphone$, app$, app*, surgery, surgical, surg*, general surgery, general surg*, bariatric$, urology and plastic surgery, ortho*, orthop(a)edic, cardiac surgery, cardiothoracic, neurosurgery, and ophthalmology. RESULTS: The search yielded 38 articles of which 23 were eligible. Each of the key specialties was searched in the Apple iTunes App Store for iPhone iOS and the Google Play Android application store. In total, there were 621 surgical applications for Apple iPhone iOS and 97 identified on Android's Google Play. There has been a 9-fold increase in the number of surgical applications available for the Apple iPhone iOS from 2009 to 2012. Of these applications there were 126 dedicated to plastic surgery, 79 to orthopedics, 41 to neurosurgical, 180 to general surgery, 36 to cardiac surgery, 121 to ophthalmology, and 44 to urology. There was a wide range of applications ranging from simple flashcards to be used for revision to virtual surgery applications that provided surgical exposure and familiarization with common operative procedures. CONCLUSIONS: Despite the plethora of surgical applications available for smartphones, there is no taxonomy for medical applications. Only 12% were affiliated with an academic institution or association, which highlights the need for greater regulation of surgical applications.
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Teléfono Celular/estadística & datos numéricos , Aplicaciones Móviles/estadística & datos numéricos , Diseño de Software , Procedimientos Quirúrgicos Operativos/métodos , Educación de Postgrado en Medicina/métodos , Femenino , Cirugía General/instrumentación , Cirugía General/métodos , Humanos , Masculino , Neurocirugia/instrumentación , Neurocirugia/métodos , Oftalmología/instrumentación , Oftalmología/métodos , Procedimientos Ortopédicos/instrumentación , Procedimientos Ortopédicos/métodos , Cirugía Plástica/instrumentación , Cirugía Plástica/métodos , Urología/instrumentación , Urología/métodosAsunto(s)
Salud Global , Promoción de la Salud/organización & administración , Neoplasias/epidemiología , Neoplasias/prevención & control , Medicina Preventiva/organización & administración , Países Desarrollados , Países en Desarrollo , Femenino , Necesidades y Demandas de Servicios de Salud , Humanos , Masculino , Mortalidad/tendencias , Prevalencia , Medición de Riesgo , Factores Socioeconómicos , Organización Mundial de la SaludRESUMEN
Childhood obesity is a serious problem in the UK, with around 20% of children aged 10-11 being overweight or obese. Lifestyle interventions can be effective, but there is limited evidence of their effectiveness in delivering sustained weight loss. The present research explored potential of web-based, 3-dimensional virtual worlds (VWs) for facilitation of weight-management, well-being and patient and public involvement (PPI) for young people. Attendees of a weight management camp took part in induction sessions for use of the VW of Second Life. All participants successfully learned how to interact with one another and navigate the virtual environment. Participant appraisals of Second Life were varied. Some found it complicated and difficult to use, and some found it fun and the majority stated that they would choose to use VWs again. There is considerable potential for use of VWs to promote weight management, and Second Life or a similar VW could be used to deliver this. Potential barriers include members of the target sample having limited access to computers with necessary system requirements for running VWs, and that some may find VW-based educational experiences unappealing or challenging to navigate. For some however, VWs may provide a useful mode for provision of education, PPI and support relating to weight management.
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Antiinfecciosos/provisión & distribución , Países Desarrollados , Países en Desarrollo , Salud Global , Pobreza , Tecnología , Accidentes de Tránsito/prevención & control , Comités Consultivos , Ambulancias , Anemia de Células Falciformes/diagnóstico , Fármacos Anti-VIH/economía , Fármacos Anti-VIH/provisión & distribución , Recuento de Linfocito CD4/normas , Recuento de Linfocito CD4/tendencias , Enfermedades Cardiovasculares/prevención & control , Mortalidad del Niño/tendencias , Preescolar , Características Culturales , Pruebas Diagnósticas de Rutina , Pie , Salud Global/normas , Salud Global/tendencias , Infecciones por VIH/diagnóstico , Infecciones por VIH/inmunología , Infecciones por VIH/prevención & control , Accesibilidad a los Servicios de Salud/normas , Accesibilidad a los Servicios de Salud/tendencias , Humanos , Hambre , Incubadoras para Lactantes/provisión & distribución , Lactante , Mortalidad Infantil/tendencias , Mosquiteros Tratados con Insecticida , Cobertura del Seguro , Malaria/prevención & control , Vacunación Masiva/normas , Vacunación Masiva/tendencias , Mortalidad Materna/tendencias , Salud Mental/normas , Salud Mental/tendencias , Organizaciones/normas , Organizaciones/tendencias , Prevención Primaria/normas , Prevención Primaria/tendencias , Prótesis e Implantes , Asociación entre el Sector Público-Privado/tendencias , Salud Rural , Seguridad , Saneamiento/normas , Saneamiento/tendencias , Tecnología/normas , Tecnología/tendencias , Medicina Tropical/normas , Medicina Tropical/tendencias , Tuberculosis/prevención & control , Vacunas Virales/economíaRESUMEN
BACKGROUND: Community-based case management of high-frequency health service users, also termed 'high-intensity users' may reduce the demand on secondary care. In the UK, experienced senior nurses 'community matrons' have been appointed to provide more care in the community and to case manage high-intensity users and prevent unnecessary hospital admission. Computerized scoring systems have been developed to help with case finding. OBJECTIVE: To evaluate how community matrons select their caseload, in particular the impact of a case finding tool, and access to computer-based systems. METHODS: We used direct observation and the think aloud protocol during case selection and a series of workshops. Analysis was based on the Framework Approach (familiarization, coding, charting, mapping and interpretation) using verbatim transcripts analysed by N-Vivo software. RESULTS: Community matrons within the same locality have different and sub-optimal caseloads. Although common elements exist in case selection, processes are modified by individuals depending on the influence of their interpersonal relationships, accessibility of computer systems and personal experience and expertise. The supporting IT system often produced data too late and while predicting admission did not identify cases amenable to community intervention. CONCLUSIONS: Inter-professional networks, personal experience and training influence the patients identified for case management. The combination of an improved case finding tool and a better defined role for community matrons could lead to more standardized and equitable case selection.
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Manejo de Caso/organización & administración , Enfermería en Salud Comunitaria/organización & administración , Toma de Decisiones Asistida por Computador , Rol de la Enfermera , Selección de Paciente , Enfermedad Crónica/enfermería , Humanos , Relaciones Interprofesionales , Readmisión del Paciente , Competencia Profesional , Reino UnidoRESUMEN
It is an exciting time for all those engaged in the treatment of colorectal cancer. The advent of new therapies presents the opportunity for a personalized approach to the patient. This approach considers the complex genetic mechanisms involved in tumorigenesis in addition to classical clinicopathological staging. The potential predictive and prognostic biomarkers which have stemmed from the study of the genetic basis of colorectal cancer and therapeutics are discussed with a focus on mismatch repair status, KRAS, BRAF, 18qLOH, CIMP and TGF-ß.
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There is a large and compelling body of epidemiological and experimental evidence that oestrogens are the fuel behind the aetiology of breast cancer. The carcinogenic effects of oestrogen are postulated to be mediated by: the stimulation of cellular proliferation through their receptor-mediated hormonal activity. Other mechanisms include; direct genotoxic effects by increasing mutation rates through a cytochrome P450-mediated metabolic activation and induction of aneuploidy. The local biosynthesis of oestrogens, especially in postmenopausal women as a result of the interactions of various enzymes, is believed to play a very important role in the pathogenesis and development of hormone dependent breast carcinoma. The over-expression of such enzymes seems to be associated with the development of a more aggressive disease process, a poorer outcome and increased local and distant recurrences.