RESUMEN
OBJECTIVE: This paper presents the results of a risk factors-analysis and the analysis of physical development of pre-school children born with a low birth weight to teenage mothers. MATERIALS AND METHODS: The study has also identifed unfavorable factors affecting the birth of low weight children and the lag in physical development of preschool children born with low birth weight to adolescent mothers. RESULTS: According to our research, children born out of wedlock are mostly born with low birth weight (66.7%) and student mothers who had psychological and physical stress during pregnancy. CONCLUSION: Adolescent mothers who lacked a sufficient and balanced diet, had a high risk of born child with IUGR of hypotrophic type of the 2nd degree.
RESUMEN
Deficiency of plasma platelet-activating factor (PAF) acetylhydrolase resulting from a missense mutation (Val279Phe) in exon 9 of the gene has been described exclusively in the Japanese population with a very high frequency. This study describes the distribution of the mutation in Turkey and two other Turkic nations, Kyrgyzstan in central Asia and Azerbaijan bordering the Caspian Sea. Among 358 unrelated healthy subjects studied from Turkish population, only 3 had the mutation in heterozygous state (0.84%). Family studies also revealed the presence of homozygous individuals in close relatives of one of these subjects. Among 143 healthy subjects studied from Kyrgyzstan, 12 were heterozygous for the mutation (8.4%). No mutation was detected among 100 healthy individuals studied from Azerbaijan. However, it was suggested that the number of subjects was not enough to draw any conclusion about the prevalence of the mutation in the populations studied. Contrary to the previous notions, identification of the mutation in Turkey and Kyrgyzstan shows the existence of the mutation in non-Japanese populations as well.