RESUMEN

Renal cysts occur in approximately 50% of patients with tuberous sclerosis complex, but their clinical significance and response to treatment are unknown. Abdominal imaging of 15 patients with tuberous sclerosis complex-associated renal cystic disease who had received mammalian target of rapamycin inhibitor therapy for other tuberous sclerosis complex-related indications was evaluated. Reductions in cyst number, sum diameter, and volume were observed.

Asunto(s)

Inmunosupresores/uso terapéutico , Enfermedades Renales Quísticas/tratamiento farmacológico , Sirolimus/uso terapéutico , Esclerosis Tuberosa/complicaciones , Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Riñón/patología , Enfermedades Renales Quísticas/etiología , Imagen por Resonancia Magnética , Masculino , Resultado del Tratamiento , Esclerosis Tuberosa/tratamiento farmacológico , Adulto Joven