RESUMEN
Our own results and the literature dates analysis showed that spontaneous endothelial cells injury in aging, and the hypertension, hypercholesterinemia, immune disorders, that was induced in experiment aggravating the process of the development of atherosclerosis.
Asunto(s)
Envejecimiento/fisiología , Vasos Sanguíneos/lesiones , Vasos Sanguíneos/fisiología , Envejecimiento/inmunología , Animales , Arteriosclerosis/sangre , Arteriosclerosis/etiología , Arteriosclerosis/fisiopatología , Vasos Sanguíneos/inmunología , Humanos , Hipercolesterolemia/complicaciones , Hipertensión/complicaciones , Lípidos/sangreRESUMEN
Development and regression of experimental atherosclerosis in rabbits is an expressed age-related phenomenon, showing the increase in occurrence and pronouncement of atherosclerotic process with age. A new approach to the disease treatment by means of olivomycin is described. It has shown that while influencing considerably the protein biosynthesis of experimental animal, one can accelerate the regression of atherosclerosis by means of olivomycin and reduce protein and lipid metabolism indicators characterizing the disease development.