RESUMEN
Sera from 260 men from Denmark and elsewhere attending two Copenhagen sauna clubs for homosexual men during nine months of 1982-1983 were investigated for markers for syphilis, hepatitis A and B, and human immunodeficiency virus (HIV). Five per cent (12 men) had active syphilis, and another 35% (92) had a history of and/or serologic markers for syphilis. Ninety-four men (36%) were positive for antibodies to hepatitis A virus, ten (4%) were positive for hepatitis B surface antigen (HBsAg), and 153 (59%) were positive for antibodies to HBsAg. Antibodies to HIV were found in 45 (20%) of the 220 men investigated for this marker. Markers for hepatitis A and B and for syphilis were more frequent in the HIV antibody-positive individuals, but the association was significant only for markers for hepatitis B (relative risk = 2.0). Thus STD markers had little predictive value for seropositivity for antibodies to HIV. Among 37 men investigated more than once, a seroconversion rate of 3% per month for antibodies to HIV was found, but this estimate must be taken with reservation. The rate of seropositivity for antibodies to HIV among men from Denmark was 23%, and three (8%) of the 40 HIV-positive Danish men developed the acquired immunodeficiency syndrome (AIDS) during the four years following the initial investigation. This study shows that by 1982-1983 HIV had spread considerably in the Danish high-risk group, although there were only seven reported cases of AIDS in the country at that time.
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/epidemiología , Anticuerpos Antivirales/análisis , Seropositividad para VIH/epidemiología , Homosexualidad , Enfermedades de Transmisión Sexual/epidemiología , Baño de Vapor , Síndrome de Inmunodeficiencia Adquirida/inmunología , Adolescente , Adulto , Anciano , Dinamarca , Seropositividad para VIH/complicaciones , Hepatitis A/epidemiología , Hepatitis A/inmunología , Hepatitis B/epidemiología , Hepatitis B/inmunología , Humanos , Masculino , Persona de Mediana Edad , Enfermedades de Transmisión Sexual/inmunología , Sífilis/epidemiología , Sífilis/inmunologíaRESUMEN
In 43 patients (28 female, 15 male) with a definitive diagnosis of disseminated sclerosis visual evoked potentials were tested several times with pattern stimulation. The average duration of the disease was 7 years before the first pattern evoked potential. The latency of the evoked potential, estimated from the first positive peak, was in the pathological range in 30 patients in the first investigation, whereas in 38 patients there was a delayed latency in the last measurement. There was an average period of 1.5 years between the first and last investigation. In 20 cases the evoked potentials showed a continuous delay in the latency. Two patients maintained the original pathological values and in 7 cases the control results were below that of the first investigation. In 9 cases it was not possible to show a definite result because of the marked fluctuation in the values. 5 times in the entire investigation was a pathological result absent. There was a clear correlation between both the duration of the disease and the presence of a delayed latency, and the frequency of episodes and a pathological latency.