RESUMEN
We studied a 71-year-old patient with sinusbradycardia due to ingestion of food. He had a history of two syncopes at lunch. Mechanical irritation of the esophagus close to the atrium as well as insufflation of air into the stomach caused bradycardia with a heart rate of 28 per minute. Bradycardia could be suppressed with atropin given intravenously. There were no abnormal roentgenographic and pathological findings regarding the esophagus and the stomach.
Asunto(s)
Bradicardia/etiología , Deglución , Síncope/etiología , Anciano , Atropina/uso terapéutico , Bradicardia/tratamiento farmacológico , Humanos , MasculinoRESUMEN
In 37 patients suffering from functional disorders of the bile duct, a multicenter collective blind study was carried out with Hyoscine-N-butyl-bromide (HBB) sugar-coated tablets (5 X 20 mg/daily), and compared with a placebo in a randomized sequence. A statistically significant therapeutic effect with HBB was confirmed on the second day of treatment both by patients and physicians. The duration of treatment seems to be an important parameter as far as the action of HBB is concerned. No atropine-like side effects occurred.
Asunto(s)
Bromuros/uso terapéutico , Enfermedades de la Vesícula Biliar/tratamiento farmacológico , Escopolamina/uso terapéutico , Diagnóstico Diferencial , Enfermedades de la Vesícula Biliar/diagnóstico , Humanos , PlacebosRESUMEN
The influence of various calcium concentrations and of the beta-sympathomimeticum orciprenaline (Alupent) on the force-frequency relationship and on the resting potentiation of isolated isometrically contracting papillary muscles of the guinea pig heart was studied. Elevation of Ca concentration and/or addition of orciprenaline augment the amplitudes of contractions elicited by rhythmical stimulation, but they diminish the amplitudes of test contractions elicited after a test interval of 1-2 s. It is suggested that calcium and orciprenaline strengthen the calcium loss from the sarcoplasmic reticulum out of the cell during a prolonged interval.
Asunto(s)
Calcio/farmacología , Corazón/efectos de los fármacos , Metaproterenol/farmacología , Animales , Cobayas , Contracción Miocárdica/efectos de los fármacos , Músculos Papilares/efectos de los fármacos , Retículo Sarcoplasmático , Factores de TiempoRESUMEN
Using the central venous oxygen saturation (SO2v) at rest and during exercise (50 Watt) a new classification of mitral valve disease is proposed, which corresponds with the recommendation of the NHA (1953). Contrary to the mostly subjective classification by clinical features, the new one results from objective hemodynamic parameters. The validity of the new proposed classification is shown using different clinical parameters.
Asunto(s)
Insuficiencia de la Válvula Mitral/clasificación , Estenosis de la Válvula Mitral/clasificación , Arritmias Cardíacas/fisiopatología , Prueba de Esfuerzo , Hemodinámica , Humanos , Insuficiencia de la Válvula Mitral/metabolismo , Insuficiencia de la Válvula Mitral/fisiopatología , Estenosis de la Válvula Mitral/metabolismo , Estenosis de la Válvula Mitral/fisiopatología , Consumo de Oxígeno , Oxihemoglobinas/análisis , Arteria PulmonarRESUMEN
Until 1974 146 patients underwent coronary surgery in Hamburg. The total mortality rate for the first 100 postoperative days was 16,3 per cent. In the last years the mortality was reduced to 14 per cent. This group included all different selective and emergency surgical procedures for coronary disease. Due to the different degree of the coronary disease and/or of the impairment of the left ventricular function the mortality ranged between 0 per cent and 35 per cent. Some clinical parameters influencing the mortality rate are discussed.