RESUMEN

Analysis of intraocular fluid and the vitreous body in 7 rabbits (14 eyes) by high performance liquid chromatography reveals histochrom metabolic products and, possibly, histrochrom itself during intravenous and subconjunctival injections and retrobulbar administration of histochrom through the irrigation system on models of experimental rabbit hyphema and hemophthalmia, which suggests that histochrom is able to penetrate across the blood-ocular barrier.

Asunto(s)

Humor Acuoso/metabolismo , Barrera Hematoacuosa/fisiología , Naftoquinonas/farmacocinética , Cuerpo Vítreo/metabolismo , Animales , Humor Acuoso/química , Cromatografía Líquida de Alta Presión , Modelos Animales de Enfermedad , Hipema/tratamiento farmacológico , Hipema/metabolismo , Conejos , Cuerpo Vítreo/química