Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 136
Filtrar
1.
Sci Rep ; 14(1): 20786, 2024 09 06.
Artículo en Inglés | MEDLINE | ID: mdl-39242784

RESUMEN

Intussusception is a common surgical emergency in children. Clinical suspicion and radiological evaluation confirm the diagnosis of the disease. Enema reduction is the first line of management. This study aimed to explore the risk factors associated with enema reduction failure. A retrospective analysis of patients diagnosed with intussusception at three different hospitals in different countries from January 2016 to December 2022. Data collected included demographics, presenting symptoms, duration of symptoms, management, outcomes, and follow-ups. A total of 290 cases of intussusception were included in the study. Ages ranged from 1 to 36 months, with a median age of 15 months. All children underwent an enema reduction which was successful in 92.4%. Failure of reduction was seen in 16.7% of females compared to 6.4% of males, and it was significantly seen in children below the age of 1 year compared to older children. Failure of reduction significantly increases with the duration of symptoms and in children who present with bilious vomiting and currant jelly stool. In conclusion, Failure of enema reduction was more prevalent in females, in children below the age of 1 year and who present late, as well as children who had bilious vomiting and currant jelly stool. This study identified several risk factors associated with failed enema reduction in children with intussusception. Recognizing the risk factors can help guide clinicians in the management and anticipation of outcomes.


Asunto(s)
Enema , Intususcepción , Insuficiencia del Tratamiento , Humanos , Intususcepción/terapia , Enema/métodos , Femenino , Masculino , Lactante , Factores de Riesgo , Preescolar , Estudios Retrospectivos
2.
Cureus ; 16(8): e66815, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39280371

RESUMEN

Myopia is the most frequent kind of refractive error and affects hundreds of millions of people. Growing evidence suggests that extended exposure to digital screens may exacerbate nearsightedness in children and young people. The purpose of this review is to compile data on the link between too much time in front of a screen and nearsightedness in young people so far. The principles of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guided the methods used and the format of the resulting report. Articles published between January 1, 2000, and June 30, 2023, were found by searching Medline, PubMed, ScienceDirect, Google Scholar, CINAHL, the Cochrane Library, and Scopus. Studies reporting an association between myopia and time spent in front of screens in children and young adults were considered eligible. The initial search yielded a total of 1,251 studies. After eliminating duplicates and reviewing the titles and abstracts, 64 full-text articles were evaluated for eligibility. Ultimately, 15 of these studies were included in the final analysis. The 15 studies involved a total of 59,775 participants and were conducted in various countries, including China, Singapore, and the United States. Overall, the evidence did not support a significant association between screen time and myopia in school children and young adults. There is conflicting evidence on the link between screen time and myopia in children and adolescents. More research is needed to determine whether or not digital screen use is a risk factor for myopia. The complex association between screen time and myopia is not fully understood at this time because of the variability of the included studies. These results have significant public health implications since they may be used to guide recommendations for screen time use in children and the young population.

3.
Malays J Pathol ; 46(2): 247-257, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39207002

RESUMEN

Congenital Adrenal Hyperplasia (CAH) is primarily caused by mutations in genes responsible to produce enzymes involved in the synthesis of cortisol, aldosterone, or both. This study aims to determine the prevalence, sociodemographic distributions, and clinical factors associated with CAH in the Malaysian population. This retrospective study reviewed laboratory records of 17-hydroxyprogesterone (17OHP) test requests received at the Institute for Medical Research, Kuala Lumpur from January 2021 to December 2021. Descriptive statistics were employed for most variables, and logistic regression analysis was conducted to determine factors associated with CAH. The dataset included a total of 775 patients (64.2%) from 1,207 test requests screened. The prevalence of newly diagnosed CAH in the year 2021 was 13.5% (n=105). The majority were Malays (15.1%), neonates (13.8%), and females (45.7%). Higher baseline 17-OHP (cOR:1.31, 95% CI:1.19, 1.45), unknown gender at birth (cOR:7.82, 95% CI:2.86, 21.37), and neonatal age group at presentation (cOR:29.3, 95% CI:12.07, 71.03) independently predict CAH. The high prevalence of CAH in our region has been speculated to be due to the cultural consanguinity norms, resulting in genetic aberrations. CAH may manifest as ambiguous genitalia, particularly in females, due to the overproduction of androgens in-utero, resulting in atypical genitalia, necessitating thorough investigation. To the best of our knowledge, the data presented are the latest report on CAH prevalence, distribution, and description of positive CAH cases in the Malaysian population. These findings are essential for further public health planning to improve the diagnostic capacity and clinical management of CAH.


Asunto(s)
Hiperplasia Suprarrenal Congénita , Humanos , Hiperplasia Suprarrenal Congénita/epidemiología , Hiperplasia Suprarrenal Congénita/diagnóstico , Malasia/epidemiología , Femenino , Masculino , Estudios Retrospectivos , Recién Nacido , Adulto , Lactante , Adolescente , Niño , Preescolar , Prevalencia , Adulto Joven , 17-alfa-Hidroxiprogesterona/sangre , Persona de Mediana Edad
4.
Materials (Basel) ; 17(14)2024 Jul 16.
Artículo en Inglés | MEDLINE | ID: mdl-39063806

RESUMEN

In recent years, laminate veneer restorations should be considered as a minimally invasive treatment option for several aesthetic reasons. This study compared direct composite veneers' and indirect ceramic laminate veneers' longevity in multiple diastema closures. A total of 28 patients with a mean age of 26 years received 60 direct resin composite (Estelite Asteria; n = 14) and 60 indirect ceramic veneers (IPS e.max Press; n = 14) on the maxillary anterior teeth with diastema closure. Veneers were evaluated at baseline and thereafter every 6 months for up to 2 years using USPHS criteria. Data were analyzed with Fisher's exact and chi-squared tests, while Kaplan-Meier curve was used to assess time to event. In total, three failures were observed in the form of debonding (n = 1) and fracture (n = 2) in the indirect ceramic veneers. No significant difference was observed between the survival rates of composite and ceramic veneers (Estelite Asteria: 93.4%, IPS e.max Press: 95%; p > 0.05). The overall survival rate was 94.2% (Kaplan-Meier). Staining (n = 11) and roughness (n = 14) were frequently observed for the resin composite veneers up to the final recall. Thereby, the preliminary results from this clinical trial comparing two veneer materials indicated that their survival rates were statistically similar. However, surface quality changes were more frequent in the composite veneer material.

5.
bioRxiv ; 2024 Jul 03.
Artículo en Inglés | MEDLINE | ID: mdl-39005318

RESUMEN

Recent years have seen intense interest in the development of point-of-care nucleic acid diagnostic technologies to address the scaling limitations of laboratory-based approaches. Chief among these are combinations of isothermal amplification approaches with CRISPR-based detection and readouts of target products. Here, we contribute to the growing body of rapid, programmable point-of-care pathogen tests by developing and optimizing a one-pot NASBA-Cas13a nucleic acid detection assay. This test uses the isothermal amplification technique NASBA to amplify target viral nucleic acids, followed by Cas13a-based detection of amplified sequences. We first demonstrate an in-house formulation of NASBA that enables optimization of individual NASBA components. We then present design rules for NASBA primer sets and LbuCas13a guide RNAs for fast and sensitive detection of SARS-CoV-2 viral RNA fragments, resulting in 20 - 200 aM sensitivity without any specialized equipment. Finally, we explore the combination of high-throughput assay condition screening with mechanistic ordinary differential equation modeling of the reaction scheme to gain a deeper understanding of the NASBA-Cas13a system. This work presents a framework for developing a mechanistic understanding of reaction performance and optimization that uses both experiments and modeling, which we anticipate will be useful in developing future nucleic acid detection technologies.

6.
Heliyon ; 10(13): e33399, 2024 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-39040329

RESUMEN

In this study, we explore a coupled system of fractional integro-differential equations with infinite delay and nonlocal conditions. This system encompasses classical derivatives of different orders and the fractional derivative of Caputo-Fabrizio type, as well as the fractional integral of the q -Riemann-Liouville operator. We introduce a novel definition of the Caputo and Fabrizio differential operators, enhancing the mathematical formulation. Our main focus is to investigate the system's fundamental properties, including existence, uniqueness, and continuous dependence. Through rigorous mathematical analysis, we establish the existence and uniqueness of solutions and examine how small perturbations in initial conditions or parameters impact the solutions. For the numerical aspect, we use the finite-trapezoidal approach, a reliable method for solving fractional integro-differential equations. We provide a concise explanation of the approach and demonstrate its effectiveness through two numerical examples. Overall, this comprehensive study contributes to the understanding of coupled systems with fractional derivatives and infinite delays, with implications for various scientific and engineering fields.

7.
Clin Exp Dent Res ; 10(3): e880, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38798134

RESUMEN

OBJECTIVE: To study the feasibility of using poly methyl methacrylate (PMMA) filament and fused deposition modeling (FDM) to manufacture denture bases via the development of a study that considers both conventional and additive-based manufacturing techniques. MATERIALS AND METHODS: Five sample groups were compared: heat and cold cured acrylic resins, CAD/CAM milled PMMA, 3D-printed PMMA (via FDM), and 3D-printed methacrylate resin (via stereolithography, SLA). All groups were subjected to mechanical testing (flexural strength, impact strength, and hardness), water sorption and solubility tests, a tooth bonding test, microbiological assessment, and accuracy of fit measurements. The performance of sample groups was referred to ISO 20795-1 and ISO/TS 19736. The data was analyzed using one-way ANOVA. RESULTS: Samples manufactured using FDM performed within ISO specifications for mechanical testing, water sorption, and solubility tests. However, the FDM group failed to achieve the ISO requirements for the tooth bonding test. FDM samples presented a rough surface finish which could ultimately encourage an undesirable high level of microbial adhesion. For accuracy of fit, FDM samples showed a lower degree of accuracy than existing materials. CONCLUSIONS: Although FDM samples were a cost-effective option and were able to be quickly manufactured in a reproducible manner, the results demonstrated that current recommended testing regimes for conventionally manufactured denture-based polymers are not directly applicable to additive-manufactured denture base polymers. Therefore, new standards should be developed to ensure the correct implementation of additive manufacturing techniques within denture-based fabrication workflow.


Asunto(s)
Resinas Acrílicas , Diseño Asistido por Computadora , Bases para Dentadura , Ensayo de Materiales , Polimetil Metacrilato , Impresión Tridimensional , Bases para Dentadura/microbiología , Polimetil Metacrilato/química , Resinas Acrílicas/química , Diseño de Dentadura , Humanos , Estudios de Factibilidad , Materiales Dentales/química , Recubrimiento Dental Adhesivo/métodos , Propiedades de Superficie , Estereolitografía , Resistencia Flexional , Dureza , Solubilidad
8.
Medicina (Kaunas) ; 60(4)2024 Mar 31.
Artículo en Inglés | MEDLINE | ID: mdl-38674234

RESUMEN

Background and Objectives: Despite the identified benefits of early implant loading, studies have questioned its advantages compared to delayed loading in edentulous patients. This study aimed to evaluate clinical peri-implant parameters and marginal bone loss around early placed and loaded mandibular implant overdentures with a 60-month follow-up. Materials and Methods: In this prospective cohort study, 43 patients were enrolled to receive 86 early loading sub-crestal dental implants through prosthetic guides. Implant overdentures were supported by two isolated implant locator attachments between two mental foramens. Clinical peri-implant parameters, including plaque index (PI), bleeding index (BI), peri-implant pocket depth (PIPD), and marginal bone loss (MBL) were evaluated using standardized techniques at 1, 12, 24, 36, 48, and 60 months follow-up. At 60 months, complications associated with implant overdentures (IOD's) were noted. The mean comparison of peri-implant clinical parameters was performed through ANOVA test. A p-value of ≤0.05 was taken as significant. Results: Out of the total 43 enrolled patients, 8 patients were lost during follow-up; as a result, 35 patients completed the 5 years follow-up. The mean values of PI, BI, and PIPD increased with no statistical difference (p > 0.05). For marginal bone loss, an increase in the mean values was noted at different time intervals with statistical differences (p < 0.001). The most common complications noted were loosening of the abutment, occlusal adjustment, retentive locator loosening and replacement, and relining of the denture. Conclusions: Early placement of IODs failed to prevent bone loss over time and was associated with complications, predominantly consisting of abutment loosening, occlusal adjustments, broken retentive locator components, relining, and rebasing.


Asunto(s)
Pérdida de Hueso Alveolar , Prótesis de Recubrimiento , Mandíbula , Humanos , Femenino , Masculino , Estudios Prospectivos , Pérdida de Hueso Alveolar/etiología , Persona de Mediana Edad , Estudios de Seguimiento , Mandíbula/cirugía , Anciano , Prótesis Dental de Soporte Implantado/métodos , Prótesis Dental de Soporte Implantado/efectos adversos , Implantes Dentales/efectos adversos , Estudios de Cohortes , Adulto
9.
Cureus ; 16(1): e51472, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38298281

RESUMEN

BACKGROUND: Individuals with diabetes are at risk of developing diabetic retinopathy, a vision-threatening complication. Regular eye examinations are crucial for early detection and management. Ensuring adherence to eye examination guidelines is essential to prevent visual impairment and blindness in this at-risk population. METHODS: This was cross-sectional study, and a validated questionnaire was physically administered among adult individuals with diabetes (both males and females) in Saudi Arabia. The data were gathered and analyzed using Statistical Product and Service Solutions (SPSS, version 26.0) software (IBM SPSS Statistics for Windows, Armonk, NY). This study took approximately three months from the period August 2023 to November 2023. RESULTS: This study found that most participants had type 1 diabetes (46.1%, n=83) and had been diagnosed for more than 10 years (49.4%, n=89). The most used management strategy (48.9%, n=88) was lifestyle changes and anti-diabetic medications. Most of the participants (93.3%, n=168) were fully aware of the severe eye complications of diabetes, as well as diabetic retinopathy and its complications (48.9%, n=88). The most common source of information about the importance of eye exams was healthcare professionals (56.7%, n=102). Most of the participants had annual eye exams (58.3%, n=105) and within the previous year, specifically related to their diabetes (62.8%, n=113). Adherence to eye examination guidelines was higher in those who had diabetes for more than 10 years (p=0.009), those who were on lifestyle changes and insulin therapy or anti-diabetic medications (p=0.030), those who were fully aware of severe eye complications and diabetic retinopathy (p=0.017 and p=0.020, respectively), and those with type 2 diabetes (p=0.001). In addition, participants who understood the importance of eye examinations had better glucose control (p=0.017), had eye examinations within the previous year (p=0.001), and had heard about the importance of eye examinations from healthcare professionals (p=0.020). The findings revealed the most common reasons for not getting an eye exam were a lack of awareness (37.8%) and distance from the hospital. CONCLUSION: To summarize, many people with diabetes do not get regular eye exams often because they are unaware of how important these exams are. Long-term diabetics who are aware of the dangers of diabetic retinopathy are more likely to heed this advice. However, adherence was linked to more frequent eye exams and better glucose control. Adherence and wide awareness must be created to improve retinopathy outcomes.

10.
BMC Oral Health ; 24(1): 271, 2024 Feb 24.
Artículo en Inglés | MEDLINE | ID: mdl-38402388

RESUMEN

BACKGROUND: In recent era, digitalization in the dental sciences has been observed in wide ranges. This cross-sectional study aimed to assess knowledge and practice of additive manufacturing (AM) in dentistry among university teaching faculty in Saudi Arabia. METHODS: A questionnaire was prepared and validated to distribute to the different dental colleges in Saudi Arabia. The questionnaire was divided into three parts: demographic information, knowledge and practices of AM among the dental teaching faculty. After receiving all the responses, descriptive statistics were used for the frequency distribution of all the responses. RESULTS: A total of 367 responses were received from the different faculty members. Most of the participants were male (67.30%), holding assistant professor (52.50%) positions in the field of prosthodontics (23.40%). In terms of knowledge, even though most of the participants were aware of AM (64.30%); however, do not understand the AM techniques (33.50). Moreover, 71.90% of the participants had no experience working with AM and only 13.60% of participants used AM in their respective dental colleges. CONCLUSION: AM techniques are not commonly used in the field of dentistry in Saudi Arabia; therefore, more platforms should have created to enhance the knowledge and practice of AM in the current population.


Asunto(s)
Odontología , Docentes , Humanos , Masculino , Femenino , Arabia Saudita , Universidades , Estudios Transversales
11.
Oral Health Prev Dent ; 22: 23-30, 2024 Jan 15.
Artículo en Inglés | MEDLINE | ID: mdl-38223958

RESUMEN

PURPOSE: To evaluate the peri-implant parameters of immediately placed and loaded mandibular overdentures over a 5-year follow-up period. MATERIALS AND METHODS: All subjects who had been advised and planned for two-implant mandibular overdenture treatment were included in this study. The peri-implant parameters -including plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) as well as marginal bone loss (MBL) - were assessed. In addition, prosthodontic parameters including abutment-, implant- and denture-related complications were assessed. Patients were evaluated at follow-up visits, scheduled at 1, 12, 24, 36, 48, and 60 months. The data distribution was analysed with the Shapiro-Wilk test. Data within follow-up categories were compared using ANOVA and the Tukey-Kramer test. A p-value < 0.05 was considered statistically significant. RESULTS: Among the 32 participants, 19 were males and 13 were females, with a mean age of 60.5 ± 7.33. The mean plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) varied over time. However, no statistically significant difference was observed in the plaque index, bleeding index and peri-implant pocket depth over time (p > 0.05). The mean value at baseline was found to be -0.9 ± 0.3. The values increased over time, with the highest value observed at 60 months 2.6 ± 0.7, which was statistically significant (p < 0.001). CONCLUSION: Immediately placed and loaded mandibular implant overdentures using two un-splinted implants with locator attachments showed acceptable PI, BI and PIPD at the 5-year follow-up. Statistically significantly greater marginal bone loss was observed from baseline to follow-up, but it was within acceptable limits. A moderate number of restorative and abutment complications were observed during the follow-up of IODs.


Asunto(s)
Pérdida de Hueso Alveolar , Implantes Dentales , Masculino , Femenino , Humanos , Persona de Mediana Edad , Anciano , Estudios de Seguimiento , Prótesis de Recubrimiento , Resultado del Tratamiento , Pérdida de Hueso Alveolar/diagnóstico por imagen , Pérdida de Hueso Alveolar/etiología , Mandíbula
12.
Sci Rep ; 13(1): 22347, 2023 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-38102173

RESUMEN

In the realm of nonlinear dynamics, the Belousov-Zhabotinsky reaction system has long held the fascination of researchers. The Belousov-Zhabotinsky system continues to be an active area of research, offering insights into the fundamental principles of nonlinear dynamics in complex systems. To deepen our understanding of this intricate system, we introduce a pioneering approach to tackle the time fractional Belousov-Zhabotinsky system, employing the Caputo and Atangana-Baleanu Caputo fractional derivatives with the double Laplace method. The solution we obtained is in the form of series which helps in investigating the accuracy of the proposed method. The primary advantage of the proposed technique lies in the low amount of calculations required and produce high degree of precision in the solutions. Furthermore, the existence and uniqueness of the solution are investigated thereby enhancing the overall credibility of our study. To visually represent our results, we present a series of 2D and 3D graphical representations that vividly illustrate the behavior of the model and the impact of changing the fractional order derivative and the time on the obtained solutions.

13.
Photobiomodul Photomed Laser Surg ; 41(12): 703-709, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38011738

RESUMEN

Objective: This 1-year prospective clinical trial was designed to assess the microbial, clinical, radiographic, and prosthetic parameters after disinfection of the implant abutment connection using Er,Cr:YSGG (erbium, chromium-doped: yttrium, scandium, gallium, and garnet) and Nd:YAG (neodymium-doped yttrium, aluminum, garnet). Materials and methods: All the patients were divided into four groups; Group I: Nd:YAG laser, Group II: Er,Cr:YSGG laser, Group III: 0.2% chlorhexidine (CHx), and Group IV: steam disinfection. Peri-implant parameters assessed included peri-implant bleeding scores (PIBS), peri-implant plaque scores (PIPS), peri-implant pocket depth (PIPD), and crestal bone loss (CBL). The peri-implant plaque samples were acquired to perform microbiological analysis to assess Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, respectively. All measurements were completed at baseline, 6 months, and 12 months postsurgery. Multiple groups were compared with the help of the Bonferroni post-hoc adjustment test (p < 0.01). Logistic regression models were utilized to assess the association between age, oral hygiene practices (brushing and flossing), and duration of implant function. Results: At the baseline level, there were no discernible differences in the peri-implant parameters between the study groups (p > 0.05). At the 6-month (p < 0.01) and 12-month (p < 0.001) follow-ups, all four study groups demonstrated a significant improvement in PIPS and PIBS, with no significant differences between the groups at baseline (p > 0.05). Based on an intergroup comparison, Group I (Nd:YAG) showed a significant decrease in PIBS when compared with the other groups. Group II showed a considerable decrease in PIPD and enhancements in CBL when compared with Groups I, III, and IV (p < 0.01). At the 6- and 12-month follow-up periods, P. gingivalis and T. denticola reduction were found to be statistically higher in Group II, whereas P. gingivalis and T. forsythia mean log CFU/mL were found to be statistically higher in Group I. Conclusions: Nd:YAG and Er,Cr:YSGG lasers both outperformed CHx and steam disinfection in terms of clinical, peri-implant, and prosthetic results when used to clean implant abutments.


Asunto(s)
Clorhexidina , Vapor , Humanos , Desinfección , Estudios Prospectivos , Prótesis e Implantes , Prostodoncia , Itrio
14.
Int J Clin Pharmacol Ther ; 61(12): 561-571, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-37796147

RESUMEN

OBJECTIVES: Urinary urgency (UU) is linked to musculoskeletal pain (MSP), and it is associated with mental health conditions. This study examined the prevalence of UU morbidity among outpatients with MSP, and the possible association of UU with psychological symptoms and vitamin D deficiency. MATERIALS AND METHODS: A cross-sectional study was conducted among 169 participants recruited from outpatient clinics at King Abdullah University Hospital in Jordan. Participants completed self-guided questionnaires that included information about MSP and UU. Psychological symptoms were evaluated using the Hospital Anxiety and Depression Scale (HADS). A blood sample was collected for measuring vitamin D levels. Regression analysis was performed to explore predictors of MSP and UU. RESULTS: Vitamin D deficiency was presented in 64.5% of participants, while UU was reported among 35.4% of MSP patients. Approximately 1/3 of participants had psychiatric symptoms (HADS ≥ 8). Regression analyses revealed a significant association between vitamin D deficiency, low calcium intake, and anxiety scores with MSP (p < 0.05), while anxiety score was a significant predictor of UU among MSP patients (adjusted OR = 4.26, p = 0.038). A moderately significant correlation between anxiety score and frequency of UU per day was also observed (r = 0.303, p = 0.041). CONCLUSION: Urinary urgency was prevalent among MSP patients and was strongly associated with anxiety symptoms. The findings suggest the importance of assessment of MSP patients for UU and the associated psychological symptoms so interventions may be potentially implemented to improve patients' health conditions.


Asunto(s)
Dolor Musculoesquelético , Deficiencia de Vitamina D , Humanos , Vitamina D , Depresión/psicología , Dolor Musculoesquelético/diagnóstico , Dolor Musculoesquelético/epidemiología , Autoinforme , Estudios Transversales , Deficiencia de Vitamina D/diagnóstico , Deficiencia de Vitamina D/epidemiología
15.
Heliyon ; 9(8): e18303, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37576316

RESUMEN

The Zr2AC MAX phases are a family of ternary carbides ceramics that possess layered structures and exhibiting exceptional properties resulting from combining the most desirable features of metals and ceramics. In addition, the Zr2AC MAX-phases exhibit numerous physical and chemical properties due to their chemical and structural characteristics, a tendency for multiple basal dislocations and exhibiting mobility under ambient conditions. This review extensively analyzes the properties of the Zr2AC MAX phase, as they are closely linked to the exceptional and potential applications of the MAX phase. For the first time, the present study analyzed various properties of Zr2AC MAX phases, including structural, electronic, elastic, thermal, optical, self-healing, nuclear, oxidation, and corrosion characteristics. Furthermore, this review included experimental and theoretical work with comparison. It's found that the Zr2AC lattice parameters a and c are deviations theoretically from 0.1 to 2% and 0.15-2.87% compared with experimental work. Also, the Zr2AC MAX phases are metallic characters and the conductivity differs depending on the type of the Zr2AC(different A element) MAX phases. Its concluded that the Zr2AC MAX phases are stiff, isotropic elastic properties and high machinability with damage tolerance and hardness levels ranging from 3.5 to 13.02 Gpa. The Zr2AC MAX phases are also resistant to corrosion, thermal shock, and oxidation as well as lightweight. In addition, at elevated temperatures the transition from brittle to plastic behavior can be occurred in the Zr2AC MAX phase. The Zr2AC MAX phase's optical properties are anisotropic such as electrical conductivity and mechanical properties. This review study provides a comprehensive details assisting researches to deal with Zr2AC MAX phase potentially for different applications.

17.
Photodiagnosis Photodyn Ther ; 42: 103630, 2023 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-37236520

RESUMEN

AIM: The aim of the present clinical trial was to study the efficacy of combined miconazole and PDT in the improvement of quality of life and levels of Candida species in chronic hyperglycemic patients with denture stomatitis (DS). METHODS: One hundred patients were randomly divided into five groups; 20 each in the miconazole, PDT, miconazole+ PDT, CHX and distilled water groups. Methylene blue mediated irradiation was conducted using 600 nm diode laser with power, energy density and radiance as 100 mW, 3527 mW/cm2 and 9 J, respectively. Patients were advised to apply 2.5 ml of 2% topical miconazole four times a day. The existence of Candida spp. was detected by means of microbiological culture technique. Candida colony counts from the palates and dentures surfaces, quantified as colony forming unit (CFU)/mL were evaluated at baseline, end of 14 days, 28 days and 60 days. Oral health related quality of life was assessed with the help of a questionnaire. RESULTS: The quality of life showed significant improvement in the group where combination treatment was executed. The overall CFU/mL values were greater in the dentures in comparison to those from the palates of the patients of all the five groups. During all time periods of the study, the CFU/mL values obtained from combination treatment group showed significant differences. Candida albicans was the most predominant yeast. CONCLUSION: This study showed the effectiveness of methylene blue- PDT in combination with miconazole in improving oral health related quality of life and significantly reducing Candida CFU counts to resolve palatal inflammation in diabetic individuals with implant-supported complete dentures.


Asunto(s)
Diabetes Mellitus Tipo 2 , Fotoquimioterapia , Estomatitis Subprotética , Humanos , Candida , Miconazol/uso terapéutico , Estomatitis Subprotética/tratamiento farmacológico , Estomatitis Subprotética/microbiología , Antifúngicos/uso terapéutico , Prótesis de Recubrimiento , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Salud Bucal , Calidad de Vida , Azul de Metileno/uso terapéutico , Fotoquimioterapia/métodos , Fármacos Fotosensibilizantes/uso terapéutico , Candida albicans
18.
Prep Biochem Biotechnol ; 53(7): 753-762, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-36332156

RESUMEN

Selection of biocarrier type is an essential element for successful bacterial cells immobilization. The present investigation aimed to evaluate a novel application of Cress and Chia seeds as biocarriers for immobilization of mixed bacterial cells. Being an environmentally friendly, non-polluting, inexpensive, and non-toxic substances makes them promising biocarriers. On the other hand, there is an increasing concern about contamination by surfactants, sodium dodecyl sulfate (SDS) is among the most commonly used surfactant. The Cress and Chia seeds were cross-linked with PVA to prepare two types of beads; CrE-PVA and ChE-PVA, respectively. The beads were utilized for the SDS biodegradation in four kinds of actual SDS-bearing wastewaters originated from; carwash garage (CWW), laundry facility (LWW), and household detergent industry (HWW), in addition to domestic wastewater (DWW). The results revealed that maximum efficiencies of SDS elimination in DWW, LWW, HWW, and CWW were 98.12, 94.32, 93.04, and 99.08%, respectively, using CrE-PVA and 99.04, 94.96, 94.71, and 99.27%, respectively using ChE-PVA. Finally, both types of beads were recycled for five times without losing their stability and efficiency for SDS biodegradation. Four kinetic models were adopted which were Blackman, Monod, Haldane, and Teissier. Results revealed that Teissier model well fitted the experimental data.


Asunto(s)
Brassicaceae , Aguas Residuales , Brassicaceae/metabolismo , Tensoactivos/metabolismo , Dodecil Sulfato de Sodio , Bacterias/metabolismo , Semillas/metabolismo
19.
Gait Posture ; 99: 133-138, 2023 01.
Artículo en Inglés | MEDLINE | ID: mdl-36435067

RESUMEN

BACKGROUND: Gait analysis has been used extensively for computing knee kinematics and kinetics, in particular, in healthy and impaired individuals. One variable assessed is the external knee adduction moment (EKAM). Variations in EKAM values between investigations may be caused by changes in static standing position, especially foot placement angles which may increase or reduce any differences seen. PURPOSE OF THE STUDY: The current study aimed to explore the influence of static trial foot position on knee kinematic and kinetic variables during walking. METHODS: Twelve healthy male participants completed three different static standing trials; 1) 20-degrees toe-in, 2) 0° and 3) 20-degrees toe-out before walking at their own pace during a lower limb kinematics and kinetics assessment. First and second peak EKAM was compared between static foot position trials, as well other knee kinematic and kinetic outcomes. Repeated measures ANOVA was used with post hoc pairwise comparison to determine the differences between static foot position trials. RESULTS: The first peak of EKAM was significantly smaller in the 20o toe-out angle, than the 20o toe-in angle (p = 0.04-8.16% reduction). Furthermore, significant changes were found in peak knee kinematics and kinetics variables (adduction angle, external rotation angle, knee flexion moment external rotation moment, abduction angle and internal rotation angle) in the different positions. CONCLUSION: Modification in static foot position between study visits may result in changes especially in the 1st peak EKAM and other kinematics and kinetics variables during walking. Therefore, standardisation of static foot position should be utilised in longitudinal studies to ensure changes in EKAM are not masked or accentuated between assessments.


Asunto(s)
Marcha , Osteoartritis de la Rodilla , Masculino , Humanos , Fenómenos Biomecánicos , Calibración , Caminata , Articulación de la Rodilla , Extremidad Inferior , Cinética
20.
Turk J Chem ; 47(4): 763-781, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38174058

RESUMEN

A unique Zr2Al-GNS MAX phase ceramic supported nanographene sheet was prepared using a cost-effective pressureless sintering technique under relatively low temperature. An experimental investigation was conducted to explore the lattice parameters using different temperatures, such as 1000, 1150, and 1300 °C. To characterize the crystal structure of the MAX phase ceramic, X-ray diffraction, field emission scanning electron microscopy imaging, energy-dispersive X-ray spectroscopy (EDX), high-resolution transmission electron microscopy (HRTEM), and selected area diffraction (SAED) were utilized. The results revealed that the pressureless sintering technique was successfully utilized to synthesize the Zr2Al-GNS MAX phase ceramic under 1150 °C with a low impurity ratio of secondary phases such as Zr3AL2, Zr3AL5, and ZrC components. The high percentage of the Zr2Al-GNS MAX phase ceramic was obtained at 49.0% at 1150 °C compared with different temperatures. The BET surface area (SBET), pore volume, and pore size were also investigated. The SBET of the prepared Zr2Al-GNS MAX phase was increased to 30% using graphene nanosheet, while the porosity was highly decreased to 8% from its original value. The electrical properties were also studied in this research for potential applications, such as the absolute value of impedance (Z), absolute value of admittance (Y), induction (L), capacitance (C), resistance (R), conductance (G), susceptibility (B), and phase angle (Ï´). It was found that the capacitance and the phase angle were improved using the prepared Zr2Al-GNS MAX phase ceramic, depending on the frequencies. The results presented here may facilitate the improvements in the features of the MAX phase type of Zr2Al-GNS-enhanced one-layer nanographene sheet for electrical applications ceramic.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA