RESUMEN
Medical reports of 8,768 patients with various diseases of thyroid gland were analyzed. There were 1,563 (17.8) male and 7,201 (82.2%) female patients aged 6 to 86 years. One-nodular goiter was diagnosed at 13.85% patients, multinodular goiter - at 67.2%, diffuse toxic goiter - at 5.85%, thyreotoxic adenoma - at 4.91%, Hashimoto's thyroiditis - at 8.16% patients. Thyroid cancer was revealed at 1.56 patients with nodular goiter, at 8.45% - with multinodular goiter, at 2.72% - with diffuse toxic goiter, at 3.71% - with thyreotoxic adenoma, and at 27.09% patients with Hashimoto's thyroiditis. Totally thyroid cancer was diagnosed at 741 (8.45%) patients including 71.12% papillary cancer, 26.47% follicular cancer and 2.42% medullar (anablastic) cancer. Some patients had metastases. It is concluded that all the patients with goiter should be operated. At diffuse toxic goiter the surgical treatment is indicated at the patients with recurrences or after 6 - 12 months of conservative treatment without clinical improvement.
Asunto(s)
Enfermedades de la Tiroides/epidemiología , Enfermedades de la Tiroides/cirugía , Adolescente , Adulto , Anciano , Bulgaria/epidemiología , Niño , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
7264 patients with different thyreopathies have been analysed, as follows: Basedov's disease (446 = 6.13%), thyreotoxic adenoma (Plummer's disease - 974 = 14.4%), nodular struma (1077 - 14.82%), polynodular struma (3291 = 45.3%), Hashimoto's thyreoiditis (1476 = 20.31%). 2879 of them have been having indications of thyreotoxicosis 39.63%). Carcinoma has been found in 908 patients = 12.5%. In the different forms, carcinoma has been found in 5.15% of the cases of Basedov's disease, 5.03% of the cases of thyreotoxic adenoma, in 8.91% of the cases of nodular struma, in 12.57% of the patients with polynodular struma, and in 32.21% of the cases of Hashimoto's thyreoiditis. The relatively high percentage of carcinoma in Hashomoto's thyreoiditis turns the disease into precancerocis. The positions of the authors are ... concerning the operative treatment of each thyreopathy.
Asunto(s)
Enfermedades de la Tiroides/cirugía , Glándula Tiroides/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Enfermedades de la Tiroides/diagnóstico , Enfermedades de la Tiroides/epidemiología , Enfermedades de la Tiroides/etiología , Resultado del TratamientoRESUMEN
Study is performed on 133 patients with vestibular disturbances with no data for inflammatory diseases. Their age group is from 30 to 60, divided into three clinical syndromes: peripheral, central and combined. The otoneurological examination is carried out after the classic clinical scheme; and the blood test is taken in the morning before breakfast. It was established some tendencies between the rate of the pathological changes in the blood protein formula, the duration of the disease and the age. Considerable dynamic changes are registered in young patients, tendency for relative hypoalbuminemia, relative hypergammaglobulinemia etc. The changed coefficient albumin/globulins which in our patients is under the average norm is analyzed. The low values of this coefficient respond to the observed tendency for hypoalbuminemia in patients with vestibular disturbances.
Asunto(s)
Proteínas Sanguíneas/análisis , Enfermedades Profesionales/sangre , Vestíbulo del Laberinto , Adulto , Envejecimiento/sangre , Femenino , Humanos , Enfermedades del Laberinto/sangre , Enfermedades del Laberinto/diagnóstico , Masculino , Persona de Mediana Edad , Examen Neurológico , Enfermedades Profesionales/diagnóstico , Caracteres SexualesAsunto(s)
Adenoma Basófilo/cirugía , Adenoma Cromófobo/cirugía , Síndrome de Cushing/terapia , Síndrome de Nelson/terapia , Neoplasias Hipofisarias/cirugía , Neoplasias Hipofisarias/terapia , Adolescente , Adrenalectomía , Hormona Adrenocorticotrópica/metabolismo , Adulto , Femenino , Humanos , Hidrocortisona/metabolismo , Hipofisectomía/métodos , Masculino , Persona de Mediana Edad , Teleterapia por RadioisótopoRESUMEN
The aim of the study is to follow up the changes in auditory and vestibular systems, common interactions between the sensory systems and the changes in some biochemical indices after vestibular loading in drivers. Several groups of drivers of heavy freight trucks were studied, aged from 25-60 and a length of service from 5 to 30 years, according to a standard programme for otoneurological examination and application of modern otoneurological methods. The biochemical investigations were performed to 32 healthy and 19 sick drivers with vestibular disorders, prior to and post vestibular provocation. The following biochemical indices were studied: serotonin, histamine, cholinesterase activity, glucose, GOT, GPT, alkaline phosphatase, calcium, potassium, sodium, chlorides, inorganic phosphorus. The biochemical changes, associated with vestibular loading of organism were established not to be strongly manifested and coming out of the frames of the normal values, nevertheless, they are significant for a given subject and should not be neglected. The data are of importance in the vocational selection of driver-applicants, prophylaxis and treatment of those working under stress situations and extreme impacts.