RESUMEN

Transition metal free Brønsted acid mediated synthesis of biologically important pyrido[1,2-a]indole scaffolds through aza-Nazarov type cyclization of readily available diaryl(2-pyridyl)methanol using formic acid has been developed. This methodology has been successfully extended to synthesize atropisomers.

Asunto(s)

Carbolinas/química , Formiatos/química , Carbolinas/síntesis química , Cristalografía por Rayos X , Ciclización , Estructura Molecular