RESUMEN

The ROS concentration and proliferation activity (Ki67 expression.marker) have been studied in the periphery blood lymphocytes of Moscow and Obninsk citizens, donors, Chernobyl disaster liquidators, inhabitants of the region contaminated after Chernobyl disaster (Klincy) and individuals with prostate cancer. It was shown that ROS concentration in lymphocytes of the liquidators and residents of the polluted region was lowered. But in lymphocytes of patients with tumors the ROS content was higher in comparison with the control. The cell content with Ki67 expression in lymphocytes of the individuals resided in the polluted region and tumor patients was lowered.

Asunto(s)

Accidente Nuclear de Chernóbil , Linfocitos/patología , Neoplasias de la Próstata/sangre , Especies Reactivas de Oxígeno/sangre , Adulto , Anciano , Anciano de 80 o más Años , Humanos , Antígeno Ki-67/sangre , Linfocitos/efectos de la radiación , Masculino , Persona de Mediana Edad , Neoplasias de la Próstata/epidemiología , Neoplasias de la Próstata/patología , Especies Reactivas de Oxígeno/efectos de la radiación