RESUMEN
In 48 children with cerebral palsy the characteristics of the squint and amblyopia were analyzed, also with respect to the features of cerebral palsy and to birth weight. Strabismus of congenital esotropia type was found to be common, as was also exotropia of early onset. Spontaneous alternation or an accommodative component of the squint was present only in a few cases. There was no evidence of an accumulation of any strabismus type in the different subgroups of cerebral palsy, whereas amblyopia or an obvious risk for amblyopia was found in the great majority of the cases. Some kind of amblyopia treatment was given to 34. Most of them showed improvement of the visual capacity which encourages treatment of amblyopia, even in children with cerebral palsy.
Asunto(s)
Parálisis Cerebral/complicaciones , Estrabismo/complicaciones , Adolescente , Parálisis Cerebral/rehabilitación , Niño , Preescolar , Femenino , Estudios de Seguimiento , Humanos , Lactante , Masculino , Factores de Riesgo , Estrabismo/fisiopatología , Estrabismo/rehabilitación , Agudeza VisualRESUMEN
We report the clinical findings in 19 Finnish patients, including six pairs of siblings, with a new, early onset spinocerebellar ataxia. The slowly progressive clinical symptoms manifested between one and two years of age in previously healthy infants. The first manifestation of children at that age was clumsiness and loss of ability to walk. Ataxia, athetosis and muscle hypotonia with loss of deep tendon reflexes were discovered on clinical examination. By school age ophthalmoplegia and hearing loss were diagnosed, while sensory neuropathy developed by adolescence. In addition, an acute crisis with status epilepticus was a late manifestation. We found a marked decrease in sensory nerve condition velocities, a progressive loss of myelinated fibers in sural nerve specimen, and abnormal background activity in EEG with advancing age. The main finding in neuroradiological investigations was cerebellar atrophy. The occurrence of the disease in siblings and lack of manifestations in parents indicate recessive inheritance.
Asunto(s)
Neuropatías Hereditarias Sensoriales y Autónomas/complicaciones , Degeneraciones Espinocerebelosas/complicaciones , Degeneraciones Espinocerebelosas/epidemiología , Adolescente , Adulto , Edad de Inicio , Sistema Nervioso Central/fisiopatología , Niño , Preescolar , Epilepsia/etiología , Femenino , Trastornos de la Audición/etiología , Neuropatías Hereditarias Sensoriales y Autónomas/genética , Neuropatías Hereditarias Sensoriales y Autónomas/patología , Humanos , Imagen por Resonancia Magnética , Masculino , Registros Médicos , Salud Mental , Músculos/fisiopatología , Linaje , Nervios Periféricos/patología , Nervios Periféricos/fisiopatología , Degeneraciones Espinocerebelosas/genéticaRESUMEN
An epidemic due to sulphonamide-resistant group A meningococci started in Finland in January 1973. By the end of 1974 the number of cases exceeded 1300. This report describes epidemiological and clinical observations in 370 patients treated in Helsinki 1973-1974. The incidence was about 65 per 100 000 per year in children under 7 years of age and about 10 per 100 000 in adults. More than one case occurred in 3.8% of the families and in 36% of the lodging-houses of the lowest social group. The fatality rate of patients treated in hospital was 4.1%. Persistent neurological damage was noticed in 4.6%.