RESUMEN
Hydrogels are three dimensional polymeric structures and are of great importance to industrial sector due to their signature physiochemical and mechanical properties. Use of natural polysaccharides as the components of hydrogel composite is of great interest due to their non-toxic nature, biodegradability, biocompatibility and viscoelastic properties. The present study reports a novel hydrogel composed of xanthan, gellan and pullulan. Unlike, pullulan and xanthan, this tri-composite formed a stable gel having high water retention ability and swelling ratio. The synergistic effects of individual components of the hydrogel on viscoelastic properties and flow behaviour were also studied. The hydrogel composite also indicated swelling ratio in alkaline environment attributed to the ionisation of hydrogel components in response to the presence of OH moieties. Overall results indicated that the composite hydrogel can have plausible application in food industry as it displays viscoelastic nature and flow behaviour index (n) values for composites within the desirable range.
Asunto(s)
Glucanos/química , Hidrogeles/química , Polisacáridos Bacterianos/química , Reología , Técnicas de Química Sintética , Concentración de Iones de Hidrógeno , Industrias , Fenómenos Mecánicos , Agua/químicaRESUMEN
Resveratrol is an important stilbene which is having a high demand due to its therapeutic, cosmeceutical and nutraceutical activities. The current study mainly focuses on strategies to enhance the fungal potential to produce resveratrol via the activation of the cryptic biosynthetic pathway with their particular interest in the antioxidant application. The endophytic fungus Xylaria psidii was isolated from the surface sterilized leaf of Vitis vinifera. With the help of HPLC analysis it is found that resveratrol concentration was maximum and enhanced in case of treatment with 5 µm SAHA (52.32 µg/mL) and by 10 µm AZA (48.94 µg/mL) followed by 10 µm SAHA (41.10 µg/mL) and 5 µm AZA (37.72 µg/mL). After treatment with different concentration of epigenetic modifiers such as HDAC inhibitors (SAHA) and dMNTs (AZA) inhibitors, a significant increase in antioxidant potential was obtained. In the case of DPPH increase in scavenging potential was found as compared to wild strain. Treatment with 5 µm SAHA and by 10 µm AZA was showing strong antioxidant potential among all the epigenetic variants as compared to wild strain. In the case of TEAC also the same trend as in the case of DPPH was obtained.