RESUMEN
In 44 patients with alveolar echinococcosis, the correlation between the results of main laboratory tests were studied and their clinical interpretation was given. It was shown that at an uncomplicated stage of the disease, the immune response suppressing the helminth growth plays the main role; at the stage of complications the pathogenetic significance of non-specific inflammatory responses caused by destructive processes increases; at a stage of decompensation the correlation reflects severe immunological abnormalities and progressive immunodepression. The obtained correlations might be used as a measure for determining the stage of the disease in the algorithmic method for the classification of alveolar echinococcosis.
Asunto(s)
Equinococosis Hepática/diagnóstico , Equinococosis Hepática/complicaciones , Equinococosis Hepática/epidemiología , Humanos , Estadística como Asunto/métodosRESUMEN
The clinical condition was assessed in 44 patients with alveolar echinococcosis, using methods of mathematical analysis of 10 basic routine laboratory parameters reflecting protein-forming liver function and immune disturbances. The data were processed on a "NOVA-2" [correction of "HOBA-2"] computer using Fortran software on taxonomy 7 classes of conditions were determined, which reflect the progressing severity of the pathological process and correspond to three stages of the disease: uncomplicated, complicated and terminal. A high clinical value of the method has been demonstrated for the evaluation of the patient's condition and determination of the treatment tactics as well as its importance for the creation of a clinical data bank in the invasion focus.