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The rise of electric vehicles (EVs) necessitates an efficient charging infrastructure capable of delivering a refueling experience akin to conventional vehicles. Innovations in Extreme Fast Charging (EFC) offer promising solutions in this regard. By harnessing renewable energy sources and employing sophisticated multiport converters, EFC systems can meet the evolving demands of EV refueling. A single-stage topology simplifies the converter design, focusing on efficient DC-AC conversion, vital for feeding solar power into the grid or charging stations. It provides power factor correction, harmonics filtering, and mitigates power quality issues, ensuring stable and efficient operations. Converters with Maximum Power Point Tracking (MPPT) capability facilitate the efficient integration of solar PV systems in charging stations, ensuring maximum solar energy utilization for EV charging. The ability to operate in different modes allows seamless integration with energy storage systems, storing excess solar energy for use during night-time or peak demand periods, enhancing overall efficiency and reliability. Advanced converters support bidirectional energy flow, enabling EV batteries to discharge back to the grid, aiding grid stability and energy management. However, robust control algorithms are needed to handle dynamic conditions like partial shading more effectively. Our review focuses on integrating renewable energy sources with multiport converters, providing insights into a novel EV charging station framework optimized for EFC topology. We highlight the advantages of multiport non-isolated converters over traditional line frequency transformers, particularly in medium voltage scenarios, offering enhanced efficiency and versatility for EFC applications.

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BACKGROUND: The adolescent and young adult (AYA) age group is a bridge between pediatric and adult age groups. The present study describes the epidemiology of cancers in the AYA age group in India. METHODS: The data of primary site cancers in the age group of 15-39 years from the 28 Population Based Cancer Registries (PBCRs') and 58 Hospital Based Cancer Registries under the National Cancer Registry Programme for the reporting year 2012-2016 was analysed. RESULTS: The median age adjusted incidence rate (AAR) was 22.2 per 100,000 among males and 29.2 per 100,000 among females. The age-specific incidence rate increased with increasing age in both genders with the highest recorded numbers in the 35-39 age group. The proportion of myeloid leukaemia and non-Hodgkin's lymphoma was highest in the 15-24 age group. Cancers of the breast, thyroid, mouth and tongue constituted the leading sites between 30 and 39 years. There was a significant increase in the incidence among AYA males (APC=0.9) between 1985 and 2015, while a decline in incidence was observed for females, which was not significant (APC=-0.2). The majority of patients had locoregional spread of cancer at the time of diagnosis. The projected number of cancer cases in both genders are expected to increase to 178,617 in 2025. CONCLUSION: Cancers in the AYA population are a concern in India. Since AYA oncology appears to be evolving in India, a robust health care system and suitable AYA cancer care policies and programmes are strongly needed to improve disease outcomes and survival.

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Mixed ligand complexes of Ni(II) with 1,10-phenanthroline (1,10-Phen) and Schiff bases L(1)(MIIMP); L(2)(CMIIMP); L(3)(EMIIMP); L(4)(MIIMNP); L(5)(MEMIIMP); L(6)(BMIIMP); L(7)(MMIIMP); L(8)(MIIBD) have been synthesized. These metal chelates have been characterized by elemental analysis, IR, (1)H-NMR, (13)C-NMR, Mass, UV-Vis, magnetic moments, and thermogravimetric (TG&DTA) analysis. Spectral data showed that the 1,10-phenanthroline act as neutral bidentate ligand coordinating to the metal ion through two nitrogen donor atoms and Schiff bases acts as monobasic bidentate coordinating through NO donor atoms. All Ni(II) complexes appear to have an octahedral geometry. The antimicrobial activity of mixed ligand complexes has been studied by screening against various microorganisms, it is observed that the activity enhances upon coordination. The DNA binding studies have been investigated by UV-Vis spectroscopy, and the experimental results indicate that these complexes bind to CT DNA with the intrinsic binding constant K(b) = 2.5 ± 0.2 × 10(5) M(-1). MTT is used to test the anticancer effect of the complexes with HL60 tumor cell. The inhibition ratio was accelerated by increasing the dosage, and it had significant positive correlation with the medication dosage.

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This work describes a bioassisted approach for the preparation of metal nanoparticles using yeast species Hansenula anomala. Gold nanoparticles were prepared using gold salt as the precursor, amine-terminated polyamidoamine dendrimer as the stabilizer, and the extracellular material from H. anomala as the bioreductant. It could also be demonstrated that, using our approach, small molecules such as cysteine can act as stabilizers as well. This synthetic approach offers a greener alternative route to the preparation of gold sols that are devoid of cellular and toxic chemical components. The ability of as-synthesized gold sol to function as biological ink for producing patterns for the analysis of fingerprints and to act as an antimicrobial reagent is evaluated. The generality of this toxin-free synthetic approach to other metals was assessed using palladium and silver.

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