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Sci Rep ; 11(1): 14565, 2021 07 15.
Artículo en Inglés | MEDLINE | ID: mdl-34267273

RESUMEN

This study was aimed at establishing the subcorticals substrates of the cognitive and visceromotor circuits of the A32 and A25 cortices of the medial prefrontal cortex and their projections and interactions with subcortical complexes in the common marmoset monkey (Callithrix jacchus). The study was primarily restricted to the nuclei of the diencephalon and amygdala. The common marmoset is a neotropical primate of the new world, and the absence of telencephalic gyrus favors the mapping of neuronal fibers. The biotinylated dextran amine was employed as an anterograde tracer. There was an evident pattern of rostrocaudal distribution of fibers within the subcortical nuclei, with medial orientation. Considering this distribution, fibers originating from the A25 cortex were found to be more clustered in the diencephalon and amygdala than those originating in the A32 cortex. Most areas of the amygdala received fibers from both cortices. In the diencephalon, all regions received projections from the A32, while the A25 fibers were restricted to the thalamus, hypothalamus, and epithalamus at different densities. Precise deposits of neuronal tracers provided here may significantly contribute to expand our understanding of specific connectivity among the medial prefrontal cortex with limbic regions and diencephalic areas, key elements to the viscerocognitive process.


Asunto(s)
Callithrix , Corteza Prefrontal/fisiología , Amígdala del Cerebelo/fisiología , Animales , Biotina/análogos & derivados , Biotina/farmacocinética , Mapeo Encefálico , Dextranos/farmacocinética , Femenino , Hipotálamo/fisiología , Masculino , Vías Nerviosas/fisiología , Corteza Prefrontal/anatomía & histología , Técnicas Estereotáxicas , Tálamo/fisiología
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