Asunto(s)
Ésteres del Colesterol , Enfermedades Pulmonares Intersticiales/etiología , Adolescente , Biopsia , Varicela/diagnóstico , Varicela/patología , Varicela/cirugía , Ésteres del Colesterol/metabolismo , Diagnóstico Diferencial , Disnea/etiología , Disnea/patología , Disnea/cirugía , Resultado Fatal , Femenino , Humanos , Pulmón/patología , Enfermedades Pulmonares Intersticiales/patología , Enfermedades Pulmonares Intersticiales/cirugía , Neumonía Viral/diagnóstico , Neumonía Viral/patología , Neumonía Viral/cirugía , Neumotórax/etiología , Neumotórax/patología , Neumotórax/cirugía , Alveolos Pulmonares/patología , Insuficiencia Respiratoria/etiología , Insuficiencia Respiratoria/patología , Insuficiencia Respiratoria/cirugíaAsunto(s)
Aorta Torácica/anomalías , Esófago/cirugía , Enfermedades de la Tráquea/etiología , Anastomosis Quirúrgica/métodos , Angiografía , Aorta Torácica/cirugía , Preescolar , Cianosis/etiología , Trastornos de Deglución/etiología , Trastornos de Deglución/prevención & control , Diagnóstico Diferencial , Disnea/etiología , Esofagoscopía , Gastrostomía , Humanos , Masculino , Selección de Paciente , Enfermedades Raras , Insuficiencia Respiratoria/etiología , Ruidos Respiratorios/etiología , Enfermedades de la Tráquea/diagnóstico , Resultado del TratamientoAsunto(s)
Ampicilina/uso terapéutico , Antibacterianos/uso terapéutico , Meningitis Meningocócica/tratamiento farmacológico , Factores de Edad , Ampicilina/farmacocinética , Antibacterianos/farmacocinética , Líquido Cefalorraquídeo/química , Líquido Cefalorraquídeo/citología , Líquido Cefalorraquídeo/microbiología , Preescolar , Monitoreo de Drogas , Glucosa/análisis , Humanos , Recuento de Leucocitos , Masculino , Meninges/efectos de los fármacos , Meningitis Meningocócica/líquido cefalorraquídeo , Meningitis Meningocócica/diagnóstico , Meningitis Meningocócica/microbiología , Pruebas de Sensibilidad Microbiana , Selección de Paciente , Penicilina G/uso terapéutico , Proteínas/análisis , Proteínas/efectos de los fármacos , Distribución Tisular , Insuficiencia del TratamientoRESUMEN
The case presented is that of a pneumonia due to cholesterol in a young girl of 13 years old. The clinical picture was that of severe progressive pulmonary fibrosis. On histology, a foreign body reaction around cholesterol crystals was found. The history enabled confirmation of the endogenous origin of this fatty infiltration.
Asunto(s)
Colesterol , Neumonía Lipoidea , Adolescente , Femenino , Reacción a Cuerpo Extraño/patología , Humanos , Pulmón/patología , Neumonía Lipoidea/diagnóstico por imagen , Neumonía Lipoidea/patología , RadiografíaRESUMEN
A statistical analysis of 248 histologically proven cases of Wilms' tumor treated at the Institut Gustave-Roussy, Villejuif, France, from 1952 to 1967, is presented. Two years recurrence-free survival and five years survival have been selected as prognostic criteria. Patients under two years of age have significantly fewer metastases and a better five-year survival rate than those over two. Stage is stronly correlated with recurrences and survival. Influence of tumor size, number of tumor nodules, tumor rupture, adhesions, regional lymph node involvement, and renal vein infiltration is shown. Detailed analysis of histopathologic features indicates that a favorable clinical course is significantly related to the number of different varieties of epithelial differentiation (tubular, glomerular, microcystic) found in any tumor, whatever the abundance of each of them. Presence of striated muscular cells, however abundant, does not influence survival or metastatic rates. Cases where irradiation given prior to surgery resulted in complete destruction of tumor cells, form a distinctive group of very unfavorable prognosis. Relapse of tumor occurs in 54% of cases, 10% presenting with metastases. Involved sites are listed. No correlation is found between date of metastases and other parameters. The three major prognostic factors of age, stage, histologic pattern, bear prognostic value separately. Stage and age are linked, as well as histology and age. Stage and histology are not linked. Age in itself therefore seems less important. It is concluded that these well-defining treatment for each individual case.
Asunto(s)
Tumor de Wilms , Factores de Edad , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Metástasis de la Neoplasia , Recurrencia Local de Neoplasia , Pronóstico , Estudios Retrospectivos , Tumor de Wilms/mortalidad , Tumor de Wilms/patología , Tumor de Wilms/terapiaRESUMEN
The clinicopathologic features of radiation enteritis are reviewed in 44 children receiving whole abdominal radiation therapy between 1961-1972 at the Institut Gustave-Roussy. Five of 14 long-term survivors (36%) developed severe delayed radiation injury with small bowel obstruction, occurring within 2 months after completion of irradiation. All had previously had acute radiation reaction during therapy. Histologic appearance in the small bowel at the time of delayed radiation injury revealed severe villus blunting, lymphatic dilatation, and moderately dense inflammatory infiltrate. All patients with delayed radiation injury showed marked clinical improvement coincident with a fractionated low-residue, low-fat diet, free of gluten and free of milk and milk products. The abnormal small bowel roentgenographs and small bowel biopsies reverted to a normal appearance in association with the diet. No exacerbation of radiation enteritis has been seen following dietary therapy.