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1.
Ophthalmic Epidemiol ; : 1-8, 2024 Aug 30.
Artículo en Inglés | MEDLINE | ID: mdl-39212457

RESUMEN

OBJECTIVE: This study aimed to assess the frequency of cataract surgery in Brazil between 2010 and 2019 and determine the impact of public policies on preventing blindness, thereby providing evidence to conduct healthcare programs. METHODS: An analytical epidemiological approach was employed, which used data from public databases, specifically the Hospital Information System (SIH-SUS) and the Outpatient Information System (SIA-SUS). We focused on cataract surgeries conducted via phacoemulsification and extracapsular cataract extraction techniques between 2010 and 2019, mainly targeting senile cataracts within the Brazilian public health system. Data were analyzed on an annual basis and stratified by region. Trends over time were assessed using generalized additive models. RESULTS: A statistically significant upward trend in cataract surgeries was observed both nationally and within the South region (p < 0.05). Nationally, there was a 40.22% increase in surgeries between 2010 and 2019. Furthermore, the surgery rate per 1000 individuals aged ≥50 years varied across regions: nationally, it was 10.85, with rates of 9.23 in the Southeast, 13.86 in the Northeast, 9.23 in the South, 11.94 in the Midwest, and 14.2 in the North. CONCLUSION: All regions of the country, a satisfactory number of cataract surgeries were performed at some point. Only the Southern region demonstrated a notable upward trend in the number of cataract surgeries. Conversely, the remaining regions failed to sustain surgical performance, hindering consistent improvement in cataract-related conditions. To accurately gauge the prevalence of blindness in Brazil, it is crucial to examine the population growth among individuals aged ≥50 years.

2.
Clinics (Sao Paulo) ; 79: 100380, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38754224

RESUMEN

PURPOSE: This study aimed to describe the behavioral patterns of data on cataract surgery performed in the Brazilian public health system before, during, and after the COVID-19 outbreak and estimate the setbacks generated by the pandemic to guide public policies. MATERIALS AND METHODS: This was an observational, longitudinal, and descriptive epidemiological study based on data retrieved from the public health system's databases of cataract surgeries performed each year and in each region from 2015 to 2022. RESULT: In Brazil, compared with the average of the 5-years preceding the pandemic, a 23 % reduction in the number of cataract surgeries was observed in 2020, followed by a 21 % increase in 2021, compensating for the majority of patients that were not operated on. However, the worsening situation of blindness caused by cataracts due to the pandemic not be avoided in the Central-West region, where unrecovered cases continue to accumulate. CONCLUSION: The COVID-19 pandemic did not worsen the situation of cataract blindness in Brazil due to the efficacy of the measures taken by the government in resuming elective surgeries. However, the auhtors recommend that the distribution of resources for cataract surgeries should consider regional discrepancies based on epidemiological data.


Asunto(s)
COVID-19 , Extracción de Catarata , Pandemias , Humanos , COVID-19/epidemiología , COVID-19/prevención & control , Brasil/epidemiología , Extracción de Catarata/estadística & datos numéricos , Estudios Retrospectivos , Catarata/epidemiología , Estudios Longitudinales , Ceguera/epidemiología , Ceguera/etiología , Ceguera/prevención & control , Masculino , SARS-CoV-2 , Femenino
3.
Clinics ; 79: 100380, 2024. tab, graf
Artículo en Inglés | LILACS-Express | LILACS | ID: biblio-1564368

RESUMEN

Abstract Purpose This study aimed to describe the behavioral patterns of data on cataract surgery performed in the Brazilian public health system before, during, and after the COVID-19 outbreak and estimate the setbacks generated by the pandemic to guide public policies. Materials and methods This was an observational, longitudinal, and descriptive epidemiological study based on data retrieved from the public health system's databases of cataract surgeries performed each year and in each region from 2015 to 2022. Result In Brazil, compared with the average of the 5-years preceding the pandemic, a 23 % reduction in the number of cataract surgeries was observed in 2020, followed by a 21 % increase in 2021, compensating for the majority of patients that were not operated on. However, the worsening situation of blindness caused by cataracts due to the pandemic not be avoided in the Central-West region, where unrecovered cases continue to accumulate. Conclusion The COVID-19 pandemic did not worsen the situation of cataract blindness in Brazil due to the efficacy of the measures taken by the government in resuming elective surgeries. However, the auhtors recommend that the distribution of resources for cataract surgeries should consider regional discrepancies based on epidemiological data.

4.
Clinics (Sao Paulo) ; 75: e1604, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32401967

RESUMEN

OBJECTIVE: To compare the effects of hydrophobic and hydrophilic materials in square-edged acrylic intraocular lenses (IOLs) on the development of posterior capsule opacification (PCO) after pediatric cataract surgery. METHODS: Patients were randomly assigned to group 1 (hydrophobic acrylic square-edged IOLs; 13 eyes) or group 2 (hydrophilic acrylic square-edged IOLs; 13 eyes). The study evaluated PCO rates using Evaluation of Posterior Capsule Opacification (EPCO) 2000 software at one, three, six and 12 months postoperatively. Postoperative measurements also included corrected distance visual acuity (CDVA), neodymium:yttrium-aluminum-garnet (Nd:YAG) capsulotomy and postoperative complications other than PCO. RESULTS: Both groups had significant increases in PCO rates after one year. Comparison of the groups showed no significant differences in the EPCO scores at three (group 1, 0.007±0.016 vs group 2, 0.008±0.014; p=0.830), six (group 1, 0.062±0.103 vs group 2, 0.021±0.023; p=0.184), or twelve months postoperatively (group 1, 0.200±0.193 vs group 2, 0.192±0.138; p=0.902). We also found no significant group differences regarding the change (delta, Δ) in EPCO scores between three and six months (group 1, 0.055±0.09 vs group 2, 0.013±0.02; p=0.113) or between six and twelve months postoperatively (group 1, 0.139±0.14 vs group 2, 0.171±0.14; p=0.567). Twenty-three percent of patients required Nd:YAG capsulotomy at the twelve-month visit. CONCLUSIONS: No differences in PCO rates were found between hydrophobic and hydrophilic acrylic square-edged IOLs in children between five and twelve years of age at one year of follow-up.


Asunto(s)
Opacificación Capsular , Catarata , Lentes Intraoculares , Resinas Acrílicas , Niño , Preescolar , Femenino , Humanos , Implantación de Lentes Intraoculares , Masculino , Facoemulsificación , Complicaciones Posoperatorias , Estudios Prospectivos , Diseño de Prótesis
5.
Clinics ; 75: e1604, 2020. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1133462

RESUMEN

OBJECTIVE: To compare the effects of hydrophobic and hydrophilic materials in square-edged acrylic intraocular lenses (IOLs) on the development of posterior capsule opacification (PCO) after pediatric cataract surgery. METHODS: Patients were randomly assigned to group 1 (hydrophobic acrylic square-edged IOLs; 13 eyes) or group 2 (hydrophilic acrylic square-edged IOLs; 13 eyes). The study evaluated PCO rates using Evaluation of Posterior Capsule Opacification (EPCO) 2000 software at one, three, six and 12 months postoperatively. Postoperative measurements also included corrected distance visual acuity (CDVA), neodymium:yttrium‐aluminum‐garnet (Nd:YAG) capsulotomy and postoperative complications other than PCO. RESULTS: Both groups had significant increases in PCO rates after one year. Comparison of the groups showed no significant differences in the EPCO scores at three (group 1, 0.007±0.016 vs group 2, 0.008±0.014; p=0.830), six (group 1, 0.062±0.103 vs group 2, 0.021±0.023; p=0.184), or twelve months postoperatively (group 1, 0.200±0.193 vs group 2, 0.192±0.138; p=0.902). We also found no significant group differences regarding the change (delta, Δ) in EPCO scores between three and six months (group 1, 0.055±0.09 vs group 2, 0.013±0.02; p=0.113) or between six and twelve months postoperatively (group 1, 0.139±0.14 vs group 2, 0.171±0.14; p=0.567). Twenty-three percent of patients required Nd:YAG capsulotomy at the twelve-month visit. CONCLUSIONS: No differences in PCO rates were found between hydrophobic and hydrophilic acrylic square-edged IOLs in children between five and twelve years of age at one year of follow-up.


Asunto(s)
Humanos , Masculino , Femenino , Preescolar , Niño , Catarata , Opacificación Capsular , Lentes Intraoculares , Complicaciones Posoperatorias , Diseño de Prótesis , Resinas Acrílicas , Estudios Prospectivos , Facoemulsificación , Implantación de Lentes Intraoculares
6.
Clinics (Sao Paulo) ; 72(9): 543-546, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29069257

RESUMEN

OBJECTIVE: To evaluate the efficiency of long-term cataract surgery using low-cost intraocular lens implantation in community campaigns. METHODS: Fifty-eight randomly selected patients were evaluated four years after phacoemulsification and Ioflex intraocular lens implantation. Causes of low visual acuity related to the intraocular lens were evaluated, and treatment costs were calculated. RESULTS: The mean age of patients was 72±10.2 years. Four years after surgery, 25 eyes (43.0%) had decreased visual acuity related to the intraocular lens: posterior capsule opacification was noted in 24 eyes (41.3%), and intraocular lens opacification was noted in one eye (1.7%). The total cost of the post-surgical complication treatments represented 6.3% of the initial budget of the entire surgical patient group. CONCLUSIONS: The efficiency of cataract surgery with low-cost Ioflex intraocular lens implantation was significantly reduced in a long-term follow-up study because postoperative complications related to intraocular lenses emerged at higher rates than when the gold-standard treatment was used.


Asunto(s)
Resinas Acrílicas/economía , Resinas Acrílicas/uso terapéutico , Implantación de Lentes Intraoculares/métodos , Lentes Intraoculares/economía , Facoemulsificación/métodos , Anciano , Anciano de 80 o más Años , Opacificación Capsular/etiología , Costos y Análisis de Costo , Estudios de Seguimiento , Humanos , Implantación de Lentes Intraoculares/efectos adversos , Implantación de Lentes Intraoculares/economía , Lentes Intraoculares/efectos adversos , Persona de Mediana Edad , Facoemulsificación/efectos adversos , Facoemulsificación/economía , Complicaciones Posoperatorias , Diseño de Prótesis , Reproducibilidad de los Resultados , Factores de Tiempo , Resultado del Tratamiento , Agudeza Visual
7.
Clinics ; 72(9): 543-546, Sept. 2017. tab
Artículo en Inglés | LILACS | ID: biblio-890729

RESUMEN

OBJECTIVE: To evaluate the efficiency of long-term cataract surgery using low-cost intraocular lens implantation in community campaigns. METHODS: Fifty-eight randomly selected patients were evaluated four years after phacoemulsification and Ioflex intraocular lens implantation. Causes of low visual acuity related to the intraocular lens were evaluated, and treatment costs were calculated. RESULTS: The mean age of patients was 72±10.2 years. Four years after surgery, 25 eyes (43.0%) had decreased visual acuity related to the intraocular lens: posterior capsule opacification was noted in 24 eyes (41.3%), and intraocular lens opacification was noted in one eye (1.7%). The total cost of the post-surgical complication treatments represented 6.3% of the initial budget of the entire surgical patient group. CONCLUSIONS: The efficiency of cataract surgery with low-cost Ioflex intraocular lens implantation was significantly reduced in a long-term follow-up study because postoperative complications related to intraocular lenses emerged at higher rates than when the gold-standard treatment was used.


Asunto(s)
Humanos , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Resinas Acrílicas/economía , Resinas Acrílicas/uso terapéutico , Implantación de Lentes Intraoculares/métodos , Lentes Intraoculares/economía , Facoemulsificación/métodos , Opacificación Capsular/etiología , Costos y Análisis de Costo , Estudios de Seguimiento , Implantación de Lentes Intraoculares/efectos adversos , Implantación de Lentes Intraoculares/economía , Lentes Intraoculares/efectos adversos , Facoemulsificación/efectos adversos , Facoemulsificación/economía , Complicaciones Posoperatorias , Diseño de Prótesis , Reproducibilidad de los Resultados , Factores de Tiempo , Resultado del Tratamiento , Agudeza Visual
10.
MedicalExpress (São Paulo, Online) ; 3(3)Apr.-June 2016. graf
Artículo en Inglés | LILACS | ID: lil-784350

RESUMEN

OBJECTIVE: To estimate the prevalence of eye diseases in the Amazon region and evaluate the efficacy, efficiency and effectiveness of community projects of visual health in underserved communities. METHODS: Retrospective, observational and ecological study, which covers the underserved communities of the Brazilian Amazon by the Amazon Project Vision 2000. The data were retrieved from a total sample of 1,276 patients. A questionnaire was applied to patients with 22 questions divided into general and health data. All patients were submitted to a complete eye examination. All project data were stored in a database for later evaluation. RESULTS: Of the 1,276 patients evaluated, 65% were female, 51.9% said they had never had an eye examination and 91% believed to have some visual problem. Emmetropia was detected in 3.8% and 47.2% had presbyopia. Cataract (16.2%) and pterygium (23.6%) were the prevalent diseases. During the project, cataract surgeries were performed in 27.6% and pterygium in 6.9% of patients. When asked why they had not operated before, 24.1% said they had no financial conditions and 55.2% because there was no specialized doctor nearby. CONCLUSION: Refractive errors, pterygium and cataract were the most common ocular findings in the population evaluated. The Amazon Project Vision 2000 provided the equipment and resources for the activities proposed, reaching the pre-defined goal.


OBJETIVO: Estimar a prevalência de doenças oculares na região amazônica e avaliar a eficácia, eficiência e efetividade dos projetos comunitários de saúde visual em comunidades carentes. MÉTODOS: Estudo retrospectivo observacional e ecológico, que abrange as comunidades carentes da Amazônia brasileira pelo Projeto Amazônia Visão de 2000. Os dados foram obtidos a partir de uma amostra completa de 1276 pacientes. Um questionário foi aplicado aos pacientes com 22 questões divididas em dados gerais e de saúde. Todos os pacientes foram submetidos a um exame oftalmológico completo. Todos os dados de projeto armazenados em um banco de dados foram para posterior avaliação. RESULTADOS: Dos 1276 pacientes avaliados, 65.0% eram do sexo feminino, 51,9% disseram que nunca tinham feito exame de vista e 91.0% acreditavam ter algum problema visual. Emetropia foi detectada em 3,8%; 47,2% tinham presbiopia. A Catarata (16,2%) e o pterígio (23,6%) foram as doenças prevalentes. Durante o projeto, cirurgias de catarata e pterígio foram realizadas em 27,6% e 6,9% da população estudada, respectivamente. Quando indagados sobre o porque de não haverem sido operados antes, 24,1% disseram que não tinham condições financeiras e 55,2% Porque não havia médico especializado nas proximidades. CONCLUSÃO: Erros de refração, pterigyum e catarata foram os achados mais comuns na população avaliada. O Projeto Amazônia Visão 2000 forneceu equipamento e recursos para as atividades propostas, atingindo a meta pré-definida.


Asunto(s)
Humanos , Salud Ocular , Servicios de Salud Comunitaria , Oftalmopatías/epidemiología , Servicios de Salud del Indígena , Catarata/prevención & control , Brasil/epidemiología , Ceguera/prevención & control
11.
Rev. bras. oftalmol ; 74(3): 189-193, May-Jun/2015.
Artículo en Inglés | LILACS | ID: lil-764235

RESUMEN

Pediatric cataract is the most common treatable cause of blindness in children. Prevalence, etiology and morphology vary with the socioeconomic development. The treatment goal is to reduce amblyopia, being difficult management especially in unilateral cases. The decision on aphakia or primary intraocular lens should be individualized as well as correction with contact lens or spectacles. The intraocular lens single-piece hydrophobic acrylic are the most implanted in children and the preferably is in the capsular bag. The Sanders-Retzlaff-Kraff theoretic (SRK/T) stressing that is described as more predictable, following Holladay I and SRK II and the recommendation is to under correction +6.0 or +8.0 dioptrias expecting the growth of the eye. The posterior capsule opacity is the most frequent complication and varies with the material choice of the lens. Glaucoma is the most serious postoperative complication and depends on the timing of the surgery, primary lens implantation and time of post surgical follow-up. The adherence to occlusion therapy with patching is critical to the visual prognosis and is determined by the child’s age and laterality of the cataract. There was significant improvement in the surgery and in IOLs, however the final visual prognosis is still not desirable.


A catarata pediátrica é a causa mais comum de cegueira tratável em crianças. Prevalência, etiologia e morfologia variam conforme o desenvolvimento sócioeconômico. O tratamento tem como objetivo diminuir a ambliopia, sendo de difícil manejo principalmente em casos unilaterais. A decisão sobre afacia ou implante primário de lente intraocular deve ser individualizado, assim como a correção com lente de contato ou óculos. As lentes intraoculares acrílicas hidrofóbicas de peça única são as mais implantadas em crianças com preferência de implante no saco capsular. A fórmula biométrica Sanders-Retzlaff-Krafftheoretic (SRK/T) é a mais precisa em pacientes pediátricos, seguida de Holladay I e SRK II, com recomendação de sob correção de +6 a +8.0 dioptrias, devido ao esperado crescimento rápido do globo ocular. A opacidade de cápsula posterior é a complicação mais frequente e varia com o material da lente a ser implantada e o glaucoma é a complicação pós-operatória mais grave e depende da idade da criança na cirurgia, implante primário de LIOs e da duração do acompanhamento pós-cirúrgico. A adesão ao tratamento oclusivo é fundamental para o prognóstico visual, sendo determinado de acordo com a idade da criança e a lateralidade da catarata. Mesmo com a melhora do tratamento cirúrgico e das lentes intraoculares o prognóstico visual final ainda não é o desejável.


Asunto(s)
Humanos , Recién Nacido , Lactante , Preescolar , Afaquia Poscatarata/rehabilitación , Extracción de Catarata , Lentes de Contacto , Catarata/congénito , Catarata/etiología , Lentes Intraoculares , Pronóstico
12.
Eye Contact Lens ; 41(3): 141-4, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25794330

RESUMEN

Corneal involvement in patients with systemic inflammatory disorders may be sight threatening, and it may be associated with a life-threatening disease. Significant systemic inflammatory diseases in this context are autoimmune connective tissue diseases, systemic autoimmune dermatological disorders, and autoimmune diseases of the lacrimal system. Keratoconjunctivitis sicca is usually the most common ocular finding in these patients. Peripheral ulcerative keratitis is a rare condition usually associated with increased ocular morbidity and also mortality, as it might act as an indicator of a more widespread vasculitis. Corneal biomechanical properties may also be altered in connective tissue diseases. Although recent studies suggest that the risk for corneal complications after ocular surgery in patients with quiescent autoimmune disease is minimal, caution is still recommended, as the knowledge about the corneal wound-healing process and the corneal biomechanical properties in these patients is not yet fully understood. This article reviews corneal abnormalities and characteristics in the setting of systemic inflammatory diseases.


Asunto(s)
Enfermedades de la Córnea/patología , Síndrome de Respuesta Inflamatoria Sistémica/patología , Humanos , Queratitis/patología
13.
Arq Bras Oftalmol ; 77(4): 222-4, 2014 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-25410172

RESUMEN

PURPOSE: To evaluate the incidence of posterior capsule opacification (PCO) four years after the implantation of a hydrophilic acrylic intraocular lens (IOL). METHODS: Fifty-eight randomly selected eyes from 58 patients were analyzed four years after phacoemulsification and Ioflex IOL implantation. The patients underwent an ophthalmic examination to detect PCO and a detailed medical history was obtained. The patients' charts were reviewed for their corrected distance visual acuity prior to the IOL implantation, as well as for one month postoperatively. The Student's t-test was used for statistical analysis. RESULTS: The mean age of patients without PCO was 74.6 ± 9.5 years, compared to 70.3 ± 15 years in patients with PCO. Four years after surgery, 39 of the 58 eyes (67%) had detectable PCO and 24 eyes (41.3%) had decreased visual acuity (VA) due to PCO. These patients were referred for Nd:YAG laser capsulotomy. Three patients (5.1%) had decreased VA due to glaucoma, IOL opacification, or age-related macular degeneration. Twelve eyes (20.7%) presented mild PCO with unchanged VA. Systemic arterial hypertension was reported by 45% of the patients, and in 3.5% of these cases this was associated with diabetes mellitus. CONCLUSION: This study found the incidence of PCO to be 67% four years after phacoemulsification and Ioflex IOL implantation.


Asunto(s)
Resinas Acrílicas/efectos adversos , Opacificación Capsular/etiología , Extracción de Catarata/efectos adversos , Implantación de Lentes Intraoculares/efectos adversos , Anciano , Opacificación Capsular/epidemiología , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Masculino , Complicaciones Posoperatorias , Agudeza Visual
14.
Arq. bras. oftalmol ; 77(4): 222-224, Jul-Aug/2014. graf
Artículo en Inglés | LILACS | ID: lil-728663

RESUMEN

Purpose: To evaluate the incidence of posterior capsule opacification (PCO) four years after the implantation of a hydrophilic acrylic intraocular lens (IOL). Methods: Fifty-eight randomly selected eyes from 58 patients were analyzed four years after phacoemulsification and Ioflex IOL implantation. The patients underwent an ophthalmic examination to detect PCO and a detailed medical history was obtained. The patients' charts were reviewed for their corrected distance visual acuity prior to the IOL implantation, as well as for one month postoperatively. The Student's t-test was used for statistical analysis. Results: The mean age of patients without PCO was 74.6 ± 9.5 years, compared to 70.3 ± 15 years in patients with PCO. Four years after surgery, 39 of the 58 eyes (67%) had detectable PCO and 24 eyes (41.3%) had decreased visual acuity (VA) due to PCO. These patients were referred for Nd:YAG laser capsulotomy. Three patients (5.1%) had decreased VA due to glaucoma, IOL opacification, or age-related macular degeneration. Twelve eyes (20.7%) presented mild PCO with unchanged VA. Systemic arterial hypertension was reported by 45% of the patients, and in 3.5% of these cases this was associated with diabetes mellitus. Conclusion: This study found the incidence of PCO to be 67% four years after phacoemulsification and Ioflex IOL implantation. .


Objetivo: Avaliar a incidência da opacificação da cápsula posterior com o implante de uma lente intraocular acrílica hidrofílica. Métodos: Cinquenta e oito olhos, de 58 pacientes, selecionados de forma aleatória, foram examinados 4 anos após a cirurgia de facoemulsificação com implante da lente intraocular Ioflex em uma campanha comunitária para pessoas carentes. Os pacientes foram submetidos ao exame oftalmológico a fim de detectar opacificação da cápsula posterior. Foi obtido histórico médico detalhado. A acuidade visual corrigida antes e 1 mês após a cirurgia foi obtida através de revisão em prontuário médico. O teste t de student foi utilizado para a análise estatística. Resultados: A idade média dos pacientes sem opacificação da cápsula posterior foi 74,6 ± 9,5 anos, e 70,3 ± 15 anos nos pacientes com opacificação da cápsula posterior. Após 4 anos da cirurgia, 39 olhos (67%) foram diagnosticados com opacificação da cápsula posterior, e 24 olhos (41,3%) tiveram redução da acuidade visual causada pela opacificação da cápsula posterior, sendo encaminhados para realização de capsulotomia com Nd:YAG laser. Três olhos (5,1%) tiveram redução da acuidade visual causada por glaucoma, opacificação da lente intraocular e degeneração macular relacionada á idade. Em outros 12 olhos (20,7%) que apresentaram opacificação da cápsula posterior, a acuidade visual ficou mantida. Dentre as doenças sistêmicas, a hipertensão arterial foi relatada por 45% da amostra avaliada e 3,5% referiram diabetes mellitus. Conclusão: O estudo encontrou incidência de 67% de opacificação da cápsula posterior na lente intraocular Ioflex 4 anos ...


Asunto(s)
Anciano , Femenino , Humanos , Masculino , Resinas Acrílicas/efectos adversos , Opacificación Capsular/etiología , Extracción de Catarata/efectos adversos , Implantación de Lentes Intraoculares/efectos adversos , Opacificación Capsular/epidemiología , Estudios de Seguimiento , Incidencia , Complicaciones Posoperatorias , Agudeza Visual
16.
Rev. bras. oftalmol ; 72(6): 366-372, nov.-dez. 2013. ilus, graf, tab
Artículo en Portugués | LILACS | ID: lil-704737

RESUMEN

OBJETIVO: Avaliar o efeito do crosslinking (CXL) no tratamento de ceratite infecciosa, resistente ao tratamento clínico, e investigar a relação com o agente etiológico. MÉTODOS: Foram incluídos 11 pacientes com diagnóstico de ceratite infecciosa de etiologia bacteriana (sete olhos) e fúngica (quatro olhos) na Fundação Altino Ventura (FAV) no período de outubro de 2011 a maio de 2012. Os pacientes incluídos estavam em uso de colírios há pelo menos sete dias e não apresentavam melhora da infecção. Estes foram avaliados antes da realização do CXL e no período pós-operatório até cicatrização da úlcera. Para realização do CXL foram instiladas gotas de riboflavina a 0,1% e dextrano a 20%, a cada cinco minutos em um período de 30 minutos antes do procedimento, e durante a aplicação da luz ultravioleta A (UVA). A córnea foi exposta à UVA com comprimento de onda de 370ηm ± 5ηm e uma irradiância de 3mW/cm2. RESULTADOS: Os pacientes com infecção bacteriana obtiveram cura do processo infeccioso após o CXL e nenhum paciente com ceratite fúngica apresentou cicatrização. Observou-se associação significante (p = 0,003) entre o agente etiológico e a cicatrização. CONCLUSÃO: O CXL mostrou-se eficaz no tratamento da ceratite bacteriana resistente ao tratamento clínico, evitando a realização de transplante tectônico. Em relação à ceratite fúngica, este procedimento não influenciou na melhora do processo infeccioso.


PURPOSE: To evaluate the effect of corneal crosslinking (CXL) in the treatment of infectious keratitis resistant to medical treatment, and investigate the relation with the CXL outcome to the etiologic agent. METHODS: The study included 11 patients who were diagnosed with bacterial (seven eyes) or fungal keratitis (four eyes) at Altino Ventura Foundation from october 2011 to may 2012. All patients were using antibiotic eye drops for at least 7 days and have had no infection improvement. Patients were evaluated prior to CXL and the postoperative period until healing of the keratitis. For CXL, eyes were first instilled with a solution containing 0.1% riboflavin and 20% dextran for 30 min at a 5-minutes interval. Riboflavin-soaked eyes were then irradiated with UVA light (370ηm ± 5ηm) at 3mW/cm2 for 30 minutes. RESULTS: Eyes with bacterial infection exhibited improvement of infectious symptoms after CXL whereas eyes with fungal keratitis showed no improvement. Thus, there was a statistically significant correlation (p = 0.003) between the etiologic agent and the effectiveness of healing. CONCLUSION: CXL was effective in the treatment of bacterial keratitis resistant to clinical treatment, eliminating the need for surgery. However, CXL was not effective in managing fungal keratitis.


Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto Joven , Persona de Mediana Edad , Queratitis/tratamiento farmacológico , Infecciones Bacterianas del Ojo/tratamiento farmacológico , Infecciones Fúngicas del Ojo/tratamiento farmacológico , Reactivos de Enlaces Cruzados/uso terapéutico , Úlcera de la Córnea/diagnóstico , Úlcera de la Córnea/tratamiento farmacológico , Antibacterianos/uso terapéutico , Antifúngicos/uso terapéutico , Agudeza Visual
17.
J Cataract Refract Surg ; 39(3): 403-7, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23317778

RESUMEN

PURPOSE: To report the incidence of late postoperative opacification of a hydrophilic acrylic foldable intraocular lens (IOL). SETTING: Altino Ventura Foundation, Pernambuco, Brazil. DESIGN: Cross-sectional study. METHODS: Patients were examined 4 years after phacoemulsification with Ioflex IOL implantation in the rural areas of Pernambuco, Brazil, as part of a community campaign for underprivileged people. The patients had a detailed ophthalmic examination to detect late IOL opacification. The patients' charts were reviewed for preexisting ocular pathology and corrected distance visual acuity (CDVA) before and 1 month after surgery. The IOL opacification was classified according to its location and severity. RESULTS: All surgeries were uneventful intraoperatively and postoperatively. Six (7%) of the 87 eyes (58 patients) examined had a diagnosis of late IOL opacification; asteroid hyalosis and high myopia were associated ocular findings in 2 of the eyes. The preoperative CDVA ranged from hand motions (HM) to 20/80. The postoperative CDVA ranged from 20/20 to 20/40 except in 1 eye with posterior segment disease. Over the 4-year follow-up, 2 of the 6 eyes had a decrease in visual acuity to HM and 20/80, respectively, as a result of late IOL opacification. They had IOL replacement and CDVA improved to 20/60 and 20/20, respectively. A third eye with severe late opacification was not referred for IOL replacement because of macular disease. CONCLUSION: Intraocular lens opacification was observed in 7% of the eyes studied. No risk factors could be determined.


Asunto(s)
Lentes Intraoculares , Facoemulsificación , Complicaciones Posoperatorias , Falla de Prótesis , Resinas Acrílicas , Anciano , Anciano de 80 o más Años , Estudios Transversales , Femenino , Humanos , Incidencia , Implantación de Lentes Intraoculares , Masculino , Polimetil Metacrilato , Estudios Prospectivos , Reoperación , Factores de Riesgo , Agudeza Visual/fisiología
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