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Int J Vitam Nutr Res ; 60(4): 392-7, 1990.
Artículo en Inglés | MEDLINE | ID: mdl-2101832

RESUMEN

We report in the present work that membrane fluidity in erythrocytes from rats under alimentary hyperlipidemia-hypercholesterolemia is slightly diminished despite the fact that in these cells the cholesterol/phospholipid molar ratio is nearly 45% higher than in erythrocytes from control animals. In addition, the erythrocyte count in the rats given the high-fat, high-cholesterol diet was normal. Only a slight reticulocytosis was observed in these animals although their erythrocytes showed a marked decrease in their ability to extrude sodium actively. A tentative explanation for these results is proposed on the basis of other findings suggesting cellular compensatory mechanisms.


Asunto(s)
Dieta Aterogénica , Eritrocitos/fisiología , Hipercolesterolemia/sangre , Hiperlipidemias/sangre , Animales , Colesterol/sangre , Eritrocitos/metabolismo , Hipercolesterolemia/metabolismo , Hiperlipidemias/metabolismo , Masculino , Fluidez de la Membrana , Fosfolípidos/sangre , Ratas , Ratas Endogámicas , Reticulocitos/metabolismo
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