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Filtering facepiece respirators (FFRs) are manufactured in discrete sizes, with some models being limited in accommodating the fit of some sex and race combinations. This study presents the development of a custom-fit respiratory protective device (RPD) which conforms to a user's facial features and flexes and moves with facial movements during use. Our design also integrates a pressure-sensing network, which continuously monitors fit and will alert the user when the fit is compromised. In this Part II of the three-part series, we design and incorporate a continuous fit monitoring system in the RPD designed in Part I to enhance its role in protecting users from inhalation hazards in an effective manner during its use. The fit monitoring system comprises a fabric-based sensor network integrated into the RPD and an Android-based App designed to alert the user when the pressure at the faceseal falls below a given threshold established during the initial configuration of the RPD for the user. We also develop algorithms for the incorporation of the sensor slots and data buses into the custom-fit RPD using the Taxonomy of Landmarks defined in Part I. We enhance the structure developed in Part I to secure the sensor network during the use of the RPD. We develop algorithms for customizing a fastening hub to suit the head profiles of individuals to enable them to don the RPD quickly, easily, effectively, and in a repeatable manner. We demonstrate the successful application of the total design methodology by creating digital prototypes for three individuals with different facial profiles and make further advances to our goal of ensuring equitable respiratory protection for all including children, for whom RPDs are currently limited.

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The COVID-19 pandemic has resulted in a surge of patients that exceeds available human and physical resources in many settings, triggering the implementation of crisis standards of care. High-quality respiratory protection is essential to reduce exposure among healthcare workers, yet dire shortages of personal protective equipment in the United States threaten the health and safety of this essential workforce. In the context of rapidly changing conditions and incomplete data, this article outlines 3 important strategies to improve healthcare workers' respiratory protection. At a minimum, healthcare workers delivering care to patients with confirmed or suspected COVID-19 should wear N95 respirators and full-face shields. Several mechanisms exist to boost and protect the supply of N95 respirators, including rigorous decontamination protocols, invoking the Defense Production Act, expanded use of reusable elastomeric respirators, and repurposing industrial N95 respirators. Finally, homemade facial coverings do not protect healthcare workers and should be avoided. These strategies, coupled with longer-term strategies of investments in protective equipment research, infrastructure, and data systems, provide a framework to protect healthcare workers immediately and enhance preparedness efforts for future pandemics.

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Today, the term "wearable" goes beyond the traditional definition of clothing; it refers to an accessory that enables personalized mobile information processing. We define the concept of wearables, present their attributes and discuss their role at the core of an ecosystem for harnessing big data. We discuss the concept of a meta-wearable and propose a transdisciplinary approach to transform the field and enhance the quality of life for everyone.

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The field of smart textile-based wearable biomedical systems (ST-WBSs) has of late been generating a lot of interest in the research and business communities since its early beginnings in the mid-nineties. However, the technology is yet to enter the marketplace and realize its original goal of enhancing the quality of life for individuals through enhanced real-time biomedical monitoring. In this paper, we propose a framework for analyzing the transition of ST-WBS from research to reality. We begin with a look at the evolution of the field and describe the major components of an ST-WBS. We then analyze the key issues encompassing the technical, medical, economic, public policy, and business facets from the viewpoints of various stakeholders in the continuum. We conclude with a plan of action for transitioning ST-WBS from "research to reality."

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Sensors are pervasive - from homes to battlefields, and everywhere in-between. Examples include microwave ovens, mobile phones, automobiles, and medical equipment. They have become such an "integral" part of our daily lives that they are not only pervasive but they are also "invisible" to the end-user. These systems are facilitating information processing anytime, anywhere for anyone. While these types of sensors and networks incorporating such sensors are relatively new in the timeline of civilization, there has been one piece of "sensing" technology that has been there since the dawn of civilization. And that is textiles, which, in today's world are indeed pervasive. Textiles (clothing) were initially used for "protection" from the environment - be it from climatic conditions or from other predators as camouflage and personal privacy. This first dimension of "protection" has been complemented by the second dimension of "aesthetics," exemplified by the success of fashion houses in modern times - from Armani to Versace.

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It is hard to place a price tag either on human life or on the quality of life. Technology is the key to enhancing the quality of life for everyone in the continuum of life from newborns to senior citizens--whether it is the safe delivery and care of undernourished premature babies, or extending the life of a senior citizen through exploratory treatments and procedures. Technology has the potential to rapidly transform healthcare and the practice of medicine by improving the quality and safety of patient care and increasing the efficiency of healthcare providers. Moreover, the healthcare industry must meet the challenge of balancing cost containment with maintenance of desired patient outcomes and this can be accomplished through the adoption of technology. Any technology that can minimize the loss of human life and/or enhance the quality of life has a value that is priceless. An overview of the key challenges facing the practice of medicine today is presented along with the need for technological solutions that can "prevent" problems. The paradigm of "e-Health" is discussed. Then, the development of the Wearable Motherboard as a "platform" for sensors and monitoring devices that can unobtrusively monitor the health and well-being of individuals (directly and/or remotely) is described. This is followed by a discussion of the applications and impact of this technology in the continuum of life--from preventing SIDS to facilitating independent living for senior citizens. Finally, the future advancements in the area of wearable, yet comfortable, systems that can continue the transformation of healthcare and e-Health to i-Health (for interactive health)--all aimed at enhancing the quality of life for humans--are presented.

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